The sequential variation of the energy metabolism of newborns from the beginning of the birth to one hour after were measured for about fifty subjects, especially considering the influences of the first birth.
The measurement was carried by the gas analysis method of expired air. The experimental results were followings.
1. The average energy consumption was 0.621Cal for 5min., from 15 to 20min. after the delivery, and 0.608Cal for 5min., immediately after the first bath.
2. The average energy consumption was 3.15Cal for one square metre of body area, for 5min., and 3.14Cal after the first bath.
3. The average energy consumption was 0.202Cal for one kilogram of body weight, for 5min., and was 0.202Cal immediately after the bath.
4. The total oxygen consumption for 5min., from 15 to 20min, after the delivery, was 0.126l, and 0.110l after the bath.
5. The R. Q. for 5min., from 15 to 20min. after the delivery, was 0.98, and 0.87 after the bath.
6. The value of Cal/5min., Cal/m²/5min., Cal/kg/5min. showed the tendency of diminishing for every five minutes from the beginning of the birth to one hour after, and no remarkable change was observed for the oxygen consumption.
7. The R. Q. value diminished from 0.98 to 0.88, for one hour observation.
Gennerally speaking, the obtained data were higher than that of shown in literatures, however, the measuring of energy metabolism of the newborns at the delivery time was not carried out by the other authors.

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The maximal breathing capacity (M. B. C.) is often measured to study the mechanism of the pulmonal ventilation, but this method presents a number of difficulties to carry out. So, recently, some attempts to measure the respiration force and its resistance quantitatively by analyzing the simple vital capacity registered on a rapid kimograph. For example, the measurement of the maximal midexpiratory flow (M. M. F.), the timed vital capacity test, the Tiffeneau test, etc. However, these tests treat only the analysis of the expiratory phase, neglecting that of the inspiratory one.
To fill up the gap of these tests, the author studied the flow patterns of the maximum rapid and deep respiration from the basal level of the maximum expiration of 148 various subjects in sitting position using the Fukuda's waterless respirometer at the fastest revolving speed (26.6mm/sec.) of the kimograph. A vertical line was drawn from the maximum point (A) of the inspiratory curve to the horizontal line of the recording paper of the kimograph, and the point B' and C' were chosen on the inspiratory and expiratory parts of the curve at the distance of 0.5 second (13.3mm on the graph) from the vertical line. At the triangle composed by three points A, B' and C', the angle ∠B'AC' (α') was measured, and following results were obtained.
1) The angle α' was approximately under 60° for healthy subjects and over 90° for the cases of pulmanary emphysema or bronchiail asthma, also for the cases of so-called obstructive ventilatory impairement.
2) For the cases of pleural adhesion or thoracoplasty, also for the cases of so-called restrictive ventilatory impairement, the angle was between 60° and 90°.
3) By the fluctional anlysis of the flow patterns of the maximum rapid and deep breathing, the maximum flow rate (cc/0.188sec.) of the inspiration and expiration were studied. It was found that the mean value of the maximal expiratory velocity of pregnant women at 8th month was lower than that of the cases of pulmonary emphysema or bronchial asthma, but the inspiratory velocity curve was as similar as that of the normal subjects.
4) Both the angle α' and the maximal inspiratory and expiratory velocity were in significant correlation with M. M. F.

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The correlation coefficients were calculated for two variates, the body weight, body height and girth of chest to the other physical measures. The calculated coefficients were almost positive.
The length to length, the weight to girth was good correlated. Considering the relation of these three principal measures to the others are linear, the regression equations were introduced, by which if body height, weight or girth of chest are measured, the other measures are estimated from these equations and vice versa.
Moreover, multiple regression equations for body height and weight were obtained. From those equations, more acurate height and weight will be estimated.

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The distribution types of the agglutination title of the horse salmonellosis, caused by Salmonella abortus equi were studied by age and by inhabiting district.
The agglutination titles were measured for the individuals inhabiting in the salmonellosis contaminated and not contaminated districts and for these which were slaughtered.
The frequency tables of the title ×20, ×40, ×80 and so on were obtained for each class of age and each district. The titles were transformed into the exponentials, for example, ×20 into 20×2 and ×80 into 20×2², and the distribution curves, title frequency versus transformed title, were determined statistically.
The results obtained were as follows.
1) In the salmonellosis contaminated districts:The distribution type of the agglutination titles for the horse group of one year of age was determined as the Log-Pólya-Eggenberger type, for the group of two years of age as the Log-Poisson type and for that of each group of three, four and five years of age as the Log-Normal type.
2) In the non-contaminat districts:
For the group of each class of age, the distribution type was determined as the Log-Poisson type.
3) In the cases of the slaughtered:
The Log-Normal type was determined.
The frequency distribution curve of the agglutination titles depends upon the difference of ages and the presence of the contamination in the inhabiting district. The mean value of the title increases as the age of horse advances, so the determination of the presence of an inapparent epidemics of the salmonellosis by measuring the agglutination title must be considered the age of the individuals.

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The photodynamic action of dyes on Escherichia coli was studied applying more than ten sorts of them known as photodynamic active or inactive and unknown.
The relation between the absorption spectra of dyes and the action spectra for the photodynamic action was examined.
The absorption spectra of the dyes were measured spectrophotometrically and the action spectra for the photosensitve dyes on E. coli were measured exposing the bacterial suspension of the dye solution to a series of monochromatic radiations at certain wave lengths applying interference filters, with a certain equivalent dosis.
The experimental results were followings.
1) Comparing the action spectra for the photodynamic action with the absorption spectra, three types of the action were classified.
The first type: The action spectrum agrees well with the absorption spectrum, namely the region of the maximum action corresponds to the region of the maximum absorption.
The second type: The phase of the action spectrum shifts to the region of the longer wave length, however the general tendency of the action spectrum and the absorption spectrum in similar.
The third type: The photodynamic action becomes linearly stronger with increase of the wavelength.
2) No common structure which characterizes the photodynamic substrate was found, namely even if the chemical structure resembles each other, it is determined that the one is active and the other is inactive.
3) Between the intensity of the fluorescence of dye and the photodynamic activity at a certain wavelength, no particular relation was found.
4) However, the structure which possesses a halogene radical at the ortho positon of quinone nucleus shows the photodynamic activity.

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The anthropometric measurements containing thirty one items such as body weight, body height, sitting height and others were carried out for about twenty thousand male Japanese selected from a certain group, which consisted of 160.000 male adults and distributed all over in Japan.
The correlation coefficients between every two measures were calculated from the randomized samples of three hundred individuals.
The results were as follows.
1) The correlation coefficient of length to length was larger than that of length to girth and that of length to width.
The correlation coefficient of girth to girth was larger than that of girth to length and girth to width and no remarkable values were found for width to width.
2) The correlation coefficient values of weight to lengths, weight to girths and weight to widths were large. Among these, the coefficients for weight to girth were the largest, then that for weight to length and the smallest were the values for weight to width.
3) Most of the correlation coefficient showed positive value, except a few showing negative, and the significance of these negative cases were discussed.

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The recent investigations on the physiological effects of tobacco smoke suggest that the study of the particle size distribution and the filtrative characteristics of the cigarette smoke would be of interest, because such information is of value in studying the retention of the smoke at lung alveoli or the upper respiratory tract.
For this purpose, the cigarette smoke, produced under various realistic conditions, was sampled with an oscillating thermal precipitator, improved by the author, and the samples were observed electronmicroscopically, on the other hand, the smoke was collected with a three stage cascade impactor, and the weight of the sample of each stage was measured.
The results obtained were as follows.
1) In the general feature of the cigarette smoke droplets, many of the larger size droplets contained small particles, probably of carbon black.
2) The cigarette smoke particles had conspicuously hygroscopic character, and they the tendency of rapid coagulation.
3) The paritcle size distribution of the smoke was variable according to the smoking portion of the cigarette or the smoking power of the smoker. In general, it could be fitted to the logarithmic gamma distribution with rather goodness.
4) The parameters of each particle size distribution were calculated, but there was no appreciable diference between plain and filter cigarette smoke.
5) From the average or the mode of the smoke particle diameter, it was evident that the stronger the smoking power was the smaller the particles were produced, and in comparison with the smoking portion the smoking of the head portion produced smaller particles.
6) From the weight of the smoke in one puff, it could be said that the smoke weight ratio of the head smoking to the rear smoking was about 1:2 and the head smoking with weak smoking power produced the smallest smoke weight.
7) As the results of the filtration efficiency test of filer-tip, the tip was more effective to the larger particles but there was no appreciable effect to smaller particles.

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Statistical researches of blood pressure measurement have been conducted by many persons. In those researches, however, the extraction of examines may be considered rather partial as the representatives of normal Japanese.
In order to reveal how the blood pressure varies in accordance with age and what relations there exist between various conditions and the blood pressure, by measuring the blood pressure systemastically with the normal healthy Japanese as the objective person, the author has therefore pursued the present study as follows:
First of all, when the author examined, as a preparatory experiment, if the blood pressure would vary in accordance with the time of measurement, from the average measured value of the examinees, the author found out that the result was not significant statistically, and that the variation of individual measured value were comparatively negligible in the morning.
So the measurement time was set in the morning.
Next, the author investigated whether or not the blood pressure would vary in accordance with the position of the examinee (lying, sitting on a chair or standing), and the author perceived a statistically significant differenc in the maximum blood pressure was measured, the examinee being set down on a chair.
It was also examined whether or not the measurement would differ according as the examiner was rich in experience or not, from which it was revealed that even a medical student with little experience could obtain as precise a result as a physician of 30 years' experience.
The author asked for the collaboration of a physician rich in bedside and clinical experiences as well as that of a medical student. The medical sudent was trained in blood pressure measurement especially for the present purpose.
After the method of measurement was investigated by the prepartry experiments above, the examinee extraction was schemed as follows. In case of the examinees be extracted according to the theory of arbitary specimen extraction, the number of examinees to be measured can be got from the next formula.
n=4S²/b²
Here, n indicates the required number of examinees, S the standard deviation of the blood pressure, b the absolute accuracy which indicates the error of average value of measurement, that is, how many mmHg of fluctuation of the blood pressure is allowed. This formula is applicable in case which the population is almost limitless in its scope and the accuracy of results is 95%.
The author set the absolute accuracy within 1mmHg for up to 50 years of age and within 2mmHg for above 50 years of age and got the required number of examinees in each grade of age, replacing in the formula the standard deviation of the highest blood pressure of man by 5 year-grades from the data of Watanbe etc, thus the author measured the blood pressure of each of 4, 280 examinees of both sexes, that is 8, 560 persons in all. These examinees were reclassified, furthermore, according to the rate of the occupational working population and local population; the measurement of the blood pressure was carried out in 12 places: Tokyo City, Kumamoto City, Kamaishi City, Akita City, Maebashi City, Moji City, Minami-Akita-gun (Akita Pref.), Ogasa-gun (Shizuoka Pref.), Kita-Gumma-gun (Gumma Pref.), Kita-Kambara-gun (Niigata Pref.), the environment of Sakaide City (Kagawa Pref.) and Usa-machi (Kôchi Pref.).
The measurement was carried out in the following order: first, the examiner asked the examinees about their age, frequency of pregnancy, dieting, luxuries. condition of work, weight and height, physical conditions, anamnesis, etc in detail. Then came the measurement.

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The 20-methyl-cholanthrene emulsions were injected to the bone marrow of femur of rats suspended in propylenglycol, rape-oil, croton-oil and saline and the tumor formation was persued during fourty-five weeks.
About ninety subjects were used for the experiments in four groups, such as the propyleneglycol's (P), the rape-oil's (R), the croton-oil's (C) and the saline's (A). The results obtained were followings.
1) The neoplastic findings in four groups were as follows. For A group, no neoplastic findings were appeared in 10 subjects, for P group, neoplastic findings were appeared 10 cases in 45 subjects, for R group, 8 cases in 22 subjects, and for C group, 9 cases in 15 subjects.
2) To classify the locations of tumors in the diaphysis region and in the epiphysis one, 21 cases were belonged to the former and 6 cases to the latter.
3) To classify the patterns of tumors, 18 cases were belonged to the polymorph-cell sarcoma, 7 cases to the fibrosarcoma and 2 cases to the spindlecell sarcoma.
4) For the rats with tumor formation, various marked changes were observed roentgenologically.
5) No metastasis to the other organs was found.
6) The transplantation of the tumor to the other subjects were succeeded in 3 cases.

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