The authors have investigated on the effect of long-term orally administered copper to rabbits. Rabbits fed with solid feed stuff containing 0.5%, 0.1%, and 0.02% of neutral acetic copper for twelve to twenty-four months were used for this experiment.
Histopathological study indicated that injurous changes of the copper were noticed in the liver and brain of rabbits fed with 0.5% and 0.1% of neutral acetic copper. In the liver, accumulation of copper and iron granules in hepatic cells located chiefly in the peripheral zone of lobuli, periportal fibrosis and mononuclear cell infiltration in the Glisson's sheath were the note-worthy findings. In the brain, Alzheimer II type of astroglia revealed scattered throughout and degeneration of small nerve cells associated with satellitosis were recognized. Even the remarkable individual difference in the degree of the pathological changes was observed, the changes described above were most predominant in rabbits fed with 0.5% neutral acetic copper.

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The effects of oral administration of glutamic and aspartic acids on ammonia metabolism under the noise or the cold condition were observed in brain, liver, and blood.
The adult male rats were administered 5mg of each of these amino acids per 100g of body weight for 10 days before the exposure to noise or cold. The procedures were carried out as in the previous report except for the administration of these amino acids.
Under the noise condition, in the method of fixing the brain in situ by immersing the whole animal in coolant, the increase in the ammonia content of brain was not observed by the administration of each of these amino acids. In the method of decapitating, however, the ammonia content of brain was significantly higher than that of the control group, but the degree of increase was evidently reduced in comparison with the non-administration.
Under the cold condition, the ammonia content of brain was not affected by these administration.
The animals given aspartic acid showed the decrease in the ammonia content of liver and blood under the noise and the control condition, further of blood under the cold condition in comparison with the non-administration. But the administration of glutamic acid caused no changes in the ammonia content of liver and blood under each of these conditions.

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The seasonal variations of gross counts of the radioactive substances in fall-out deposited on leaf-vegetables, rinsed vegetables and that in milk were previously reported by the author. This report deals with additional foodstuffs such as short-necked clam, fruits and other standard foods recommended by the National Laboratory of Dietics for normal adult Japanese. The following results were obtained;
(1) Gross counts of the radioactive substances in fall-out deposited on leaf-vegetables decreased continuously since November in 1961 and about a-thousandth of its count were observed in 1965.
(2) Gross counts of the radioactive substances in fall-outs on leaf-vegetables and that contained in vegetable itself varied seasonally, i.e., increased in winter, decreased gradually untill autumn and then increased again in winter.
(3) Remarkable seasonal variations on the gross counts of radioactive substances in raw milk and pasteurized milk were not observed, but a little lower counts were observed in Jan. and Feb.
(4) Higher gross counts of radio active substances were observed in perennial fruits, such as pear and grape in comparison with water melon and the annual fruits.
(5) Gross counts of the radio active substances in shortnecked clam increased in May and June, but the value decreased gradually untill winter and were observed the lowest value in Jan. and Feb.
(6) The different value of radio activity in each standard foodstuffs was observed between 1958 and 1959. But the total value of each year was almost the same.
(7) The ¹³⁷Cs was found in all materials by a nuclear analysis of radio active substances.

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Synopsis:
The significance of the bodily flexibility has long been discussed in Japan from the viewpoint of medical science, pedagogy, and Physical education, but its true nature still remains to be clarified.
Recently, however, its importance has been recognized here and the Ministry of Education and the Japanese Society of Physical Education have respectively published their simplified methods.
This is indeed a step forward in the field of physical education, but a closer methodological examination reveals some contradictions and drawbacks in their methods. For instance, either of them can be applied only to the measurement of the trunk flexion and trunk extension, no mension being made of that of sideward bend or sideward rotation, or of the minute measurement of each part of a body which they are incapable of.
Thus pointing out contradictions of the Education Ministry and Physical Society formulas, the author has devised an entirely new flexibility measurement instrument based on the angular formula with the aid of available domestic and foreign literature, thereby putting forward a new measurement method, universally applicable to all parts of a body. A detailed explanation will be given in the article which is to appear in the next issue.
Conclusion:
1) In the case of the distance-formula measurement adopted by the Ministry of Education and the Japanese Society of Physical Education, the physical difference of examinées should be taken into consideration as a foreign element: therefore these methods are unsuitable for the indication of pure flexibility. (The measurement error is shown in the text.)
2) In the case of the distance-formula the difference between the length of legs and that of trunk of the examinées (here for convenience' sake the length of trunk being the distance between spina iliaca anterior superior and acromion) is a substantial controlling factor to the measurement value of the elements that constitute a human body.
3) The adoption of flexibility method based on the angular formula makes it possible to eliminate the above-mentioned foreign elements, thus facilitating the comparison of flexibility between the examinées different in age, sex, and physique.
4) With the author's flexibility instrument the flexibility of all the joints of a body as well as that of trunk flexion and extension and of sideward bend and rotation can be easily measured.
5) In the flexibility measurement of the trunk the standing posture affords more reliability than the sitting posture with a smaller coefficient of variance.
6) Of the flexibility measurement methods of the trunk, some methods which to the present writer seem of universal validity are shown in the following text.

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Manifestation of oxyuriasis occurring in mothers and their children was investigated as found in the following results.
1. In the housewives of 58 households, each of whom had a child or children, the presence of eggs of E. vermicularis in the anal and perianal regions was examined. In thirteen (22.4 per cent) of the housewives, harboring such eggs was found. Twenty-six (86.6%) out of 30 children living with these families were also revealed to have eggs of E. vermicularis. Of 105 children of 45 housewives who gave negative results in eggs of E. vermicularis, 26 children (24.7 per cent) were proved to harbor the eggs.
2. The relationship between age and rate of positive detection of eggs of E. vermicularis among mothers and their children both of whom had given positive egg tests, showed that a relatively high positive rate was found in age groups of 26 to 30 and 31 to 35 years among the mothers and in a age group of 10 years of the children.
From these results, it is presumed that these children, including infants, may constitute an important source of infection with E. vermicularis for their mothers.
3. The housewives of 90 households without children gave all negative results in the eggs of E. vermicularis.

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