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Volume 31 (1976 - 197･･･
- Issue 6 Pages 637-
- Issue 5 Pages 575-
- Issue 4 Pages 477-
- Issue 3 Pages 393-
- Issue 2 Pages 331-
Volume 31, Issue 3
Displaying 1-8 of 8 articles from this issue
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Reiko Kurayama, Isao Nakamura, Yukio Takizawa1976 Volume 31 Issue 3 Pages 393-398
Published: August 31, 1976
Released on J-STAGE: February 17, 2009
JOURNAL FREE ACCESSThis is a report of the dynamic aspects of the selective accumulation of mercury binding protein in the kidney and liver from mice injected with HgCl2. Mercury present in the kideny and liver was bound to the low (M.W. about 10, 000) and high molecular weight fractions of supernatant on Sephadex G-75.
At the start after dosing, a large amount of mercury in the kidney was bound to the high molecular weight protein, while mercury in the liver bound almost bisectionally to the both low and high molecular weight proteins. Mercury of the low molecular weight fractions of the kidney and liver increased gradually with time.
In the mice repeatedly exposed, amount of mercury in the kidney increased in the low molecular weight fraction, but the distribution of mercury binding protein of the liver remained almost unchanged.View full abstractDownload PDF (704K) -
Tadaschige Mori, Miyako Ohmoto, Atuko Ishimi, Kazuko Ohba, Shinji Akas ...1976 Volume 31 Issue 3 Pages 399-403
Published: August 31, 1976
Released on J-STAGE: February 17, 2009
JOURNAL FREE ACCESSIt is well known that water colours and poster colours are made of inorganic pigments that then contain metals such as Cr, Pb, Fe, Co, Cd, Hg etc.. Recently, promoting the culture of sentiments, children practice painting with their fingers using water colours and poster colours, that is called the finger-painting. It is possible that inorganic metals contained in water colours and poster colours are potentially hazardous to children who practice painting in a private school. Each of four colours of red, blue, yellow and green of water colours and poster colours was analyzed for Cr, Pb, Fe, Co, Cd and Hg. And urinary Pb and Cd were determined on twenty five children, ages 4 to 11 of a private school of the painting and five control children ages 3 to 11. The following results were obtained.
1) On the whole, water colours and poster colours contained a large quantity of Fe and Pb next to Fe. Especially yellow-2 of water colours contained a large quantity of Pb and showed 1, 012.5μg/g. The dissolved lead was found in water colours that were in lead tubes.
2) The average of urinary Pb of tested children was 6.07±6.67μg/l(n=15), and that of control children 2.20±2.59μg/l(n=5). There were not significant difference at levels of 5% between the mean of subjects and that of the control.
3) The average of urinary Cd of subjects was 0.68±0.94μg/l(n=25), and that of the control 0±0μg/l(n=5). There were not significant difference at levels of 5% between the mean of subjects and that of the control.
4) The coefficient of correlation between experimental length in years and urinary Pb was 0.98, its regression line being yPb=3.18x+2.17(±2.92) as yPb for urinary Pb and x for experimental length in years.
5) The coefficient of correlation between experimental length in years and urinary Cd showed 0.91, its regression line being yCd=0.23x+0.11(±0.25) as yCd for urinary Cd and x for experimental length in years.
6) The coefficient of correlation between ages and urinary Pb was 0.10, and that between ages and urinary Cd was 0.72. Urinary Cd was apt to increase in proportion to ages.View full abstractDownload PDF (594K) -
Seasonal Variations in Basal Metabolic Rate on Civilian Japanese and Caucasians in JapanCherng Hsyoung Chen1976 Volume 31 Issue 3 Pages 404-416
Published: August 31, 1976
Released on J-STAGE: February 17, 2009
JOURNAL FREE ACCESS -
Seasonal Variations in Serum Protein Bound Iodine on Civilian Japanese and Caucasians in JapanMutsuyoshi Tsuchimoto1976 Volume 31 Issue 3 Pages 417-432
Published: August 31, 1976
Released on J-STAGE: February 17, 2009
JOURNAL FREE ACCESS -
Seasonal Variation in Serum FFA on Civilian Japanese and Caucasians in JapanTomoko Aga1976 Volume 31 Issue 3 Pages 433-444
Published: August 31, 1976
Released on J-STAGE: February 17, 2009
JOURNAL FREE ACCESS -
I. On the dose-response relationship between the amount of tuna consumed and the numerical aberration of lymphocyte chromosomeMichiko Shiramizu, Shunsuke Kaku, Nobuhiro Shimojo, Kenichi Sano, Seiy ...1976 Volume 31 Issue 3 Pages 445-452
Published: August 31, 1976
Released on J-STAGE: February 17, 2009
JOURNAL FREE ACCESSA positive correlation between the amount of mercury contaminated tuna intake and the amount of mercury in the human scalp hair has been observed in both the epidemiological and the experimental studies, and also the evidence showed the positive dose-response relationship between the amount of intake of methyl mercury incorporated in mercury contaminated fishes and the concentration of mercury in blood samples. However, other problem for health effects of long-term tuna diet has not been obvious.
In order to determine the health effects of long-term tuna diet, the cats fed with tuna meat in this experiment for more than two years have been observed for the accumulation of mercury in vaious organs and related health effects including the numerical aberration of lymphocyte chromosome.
The experimental cats were divided into two groups according to the mercury levels in the tuna. The first group were given tuna of mercury level 0.665ppm, and the second group were given tuna of mercury level 0.995ppm.
A comparison was made on the concentration of mercury in the biological specimens between control and experimental groups, and the mercury levels in the experimental groups were obviously higher than those in the control group. Also, the cats in the second group showed more frequent and significant symptoms than those of the first group.
The percentage frequences of the numerical aberration of lymphocyte chromosome in the control group, the first group and the second group were 3.62, 29.3 and 62.5%, respectively. The difference in each group was statistically significant.View full abstractDownload PDF (7726K) -
Masayoshi Yamaguchi, Takeo Yamamoto1976 Volume 31 Issue 3 Pages 453-456
Published: August 31, 1976
Released on J-STAGE: February 17, 2009
JOURNAL FREE ACCESSThe effect of tin on gastric secretion in rats was examined. The volume, acidity, and total acidity of gastric contents showed a remarkable reduction in rats administered orally with tin (3.0mg/100g body weight) during 3 days. Also, acidity and total acidity of gastric contents in rats that had fasted for 24 hours significantly decreased 6 hours after a single oral administration of tin (3.0mg/100g). An oral administration of tin to rats that had fasted for 24 hours diminished the acidity and total acidity of gastric contents with the three dose (1.5, 3.0 or 5.0mg of Sn/100g) of tin employed, while did not alter the volume. On the other hand, the volume, acidity, and total acidity of gastric contents in rats that had fasted for 24 hours significantly reduced 1 hour after a single intraperitoneal injection of tin (3.0mg/100g), while it had no effect after 6 hours of fasting. The present study indicates that tin inhibits gastric secretion of rats.View full abstractDownload PDF (242K) -
Report 1. Health Hazards among Workers and Residents at Toroku MineTakeo Ohta, Tsuyoshi Nagira, Masanori Goto, Takanori Ogawa, Hiroshi Un ...1976 Volume 31 Issue 3 Pages 457-464
Published: August 31, 1976
Released on J-STAGE: February 17, 2009
JOURNAL FREE ACCESSThere was an old mine in the Toroku district in Miyazaki Prefecture, where the yields were arsenic, lead, tin, zinc etc. Arsenic ore had been mined and refined until 1962.
The miners suffered from verious diseases caused by occupational hazards, because they were assumed to have worked under very poor and deleterious conditions. The residents living in the vicinity of the mine likewise suffered through the ecological cycle caused by the environmental contamination: water pollution, contamination of crops and other products.
After mass examination provided by the Prefectural Government in 1974, the National Government recognized the district officially as “polluted district by arsenic” and the forty-eight persons who had air and worked or lived there as “the patients with chronic arsenic poisoning”.
Many residents have, however, protested against this Governmental conclusion as insufficient, because the poisoning was diagnosed simplly from the limited symptoms such as nasal perforation, skin eruption and pigmentation, and several other severe symptoms were excluded.
The authors performed an epidemiological survey including medical examination of 104 persons, 37 males and 67 females, in October 1974. The residents of the area near the Toroku district were examined and used as controls.
The results were as follows:
1) Many persons among the residents of the district had complaints such as headache, general fatigue, sleeplessness, emaciation, disturbance of vision, conjunctival hyperemia, epihora, nasal hypersecretion, huskiness, cough, sputum, wheeze, palpitation, abdominal pain, low back pain, stiffness on their shoulders, myalgia in their upper limb and so on. Arsenic eruption and hypoesthesia of their extremities were also observed.
2) The authors suggested that health hazards mentioned above were not caused only by arsenic but also by sulfer oxide and other metals such as lead, zinc and tin.
3) The authors pointed out that the measures by the central and local governments were not sufficient to provide medical and health care for the sufferers in that district.View full abstractDownload PDF (1240K)
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