生物物理
Online ISSN : 1347-4219
Print ISSN : 0582-4052
ISSN-L : 0582-4052
検索
詳細検索
OR
閲覧
検索
57 巻, 6 号
通巻334号
選択された号の論文の16件中1～16を表示しています
すべての抄録を表示する
    • |<
    • <
    • 1
    • >
    • >|
巻頭言
総説
  • 増殖・進化適応系に内在する情報熱力学的構造
    小林 徹也, 杉山 友規
    2017 年 57 巻 6 号 p. 287-290
    発行日: 2017年
    公開日: 2017/11/30
    DOIhttps://doi.org/10.2142/biophys.57.287
    ジャーナル フリー
    抄録を表示する抄録を非表示にする

    The adaptability to ever-changing environment is one of the fundamental characteristics that differentiates living matters from non-living ones. The combination of passive adaptation by Darwinian evolution and active adaptation by sensing and decision-making shapes the mechanisms of adaptability. In this work, we outline that the biological adaptation shares a very similar structure with the stochastic and information-thermodynamics. Fitness, the macroscopic quantity to characterize evolutionary success, plays the similar role as the free energy in this structure. The fluctuation relation of fitness and information derived from the structure can be regarded as an extension of the concept of the evolutionary stable strategy.

    抄録全体を表示
    PDF形式でダウンロード (541K)
  • コレラ菌タウリン・アミノ酸走性受容体の同定とそのリガンド認識機構
    西山 宗一郎, 高橋 洋平, 今田 勝巳, 川岸 郁朗
    2017 年 57 巻 6 号 p. 291-295
    発行日: 2017年
    公開日: 2017/11/30
    DOIhttps://doi.org/10.2142/biophys.57.291
    ジャーナル フリー
    電子付録
    抄録を表示する抄録を非表示にする

    Vibrio cholerae, an etiological agent of cholera, is attracted by various amino acids and taurine, a component of bile. A chemoreceptor homolog (Mlp37) was found to mediate taxis to both taurine and amino acids. Direct binding of taurine and amino acids to the periplasmic fragment of Mlp37 was observed by isothermal titration calorimetry. Ligand-occupied structures of the Mlp37 fragment revealed that the ligand-binding pocket has an opening, large enough to accommodate a larger side chain, and contains several common residues that can interact with taurine and different amino acids without substantial displacements. This structural information allowed us to visualize ligand binding to Mlp37 with fluorescently labeled serine.

    抄録全体を表示
    PDF形式でダウンロード (695K)
トピックス
理論/実験 技術
談話室
支部だより
若手の会だより
海外だより
書評
用語解説
    • |<
    • <
    • 1
    • >
    • >|
feedback
 Top