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Volume 14 (1974)
- Issue 4 Pages 251-
- Issue 3 Pages 139-
- Issue 2 Pages 67-
- Issue 1 Pages 1-
Volume 14, Issue 2
Displaying 1-9 of 9 articles from this issue
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Satoshi Tanaka, Nobuyoshi Shimizu, Takehiro Nakajima, Kensaku Ono, Nao ...1974 Volume 14 Issue 2 Pages 67-77
Published: June 25, 1974
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSResults of surgical treatment for 31 cases of anaplastic carcinoma of the lung were surveyed and indication for pulmonary resection on the small cell anaplastic carcinoma was discussed, comparing with that of the large cell anaplastic carcinoma, particularly from clinicopathological point of view.
In the small cell carcinoma, none of the cases had survival more than 2 years and 1 month affer the surgery and prolongation of survival time was not obtained, even when the operation was completely curative, if tumors held any one of the following factors; size of more than 3cm. in diameter, microscopically demonstrable nodal metastasis, occupation of central pulmonary region proximal to segmental bronchi and involvement of tissue or organ adjacent to the lung. Furthermore, eradication of cancer by pneumonectomy had no advantage over lobectomy for an improvement of the result.
In case of the large cell carcinoma, on the other hand, long term survivors more than 5 years did exist even among those who had the tumor larger than 3cm. in size and/or with intrapulmonary nodal metastasis, if they were less than 5cm. in size, and located in the peripheral site of the lung. Additionally, when tumors showed.an invasion to organs adjacent to the lung, a conbined resection was successful, in a few cases, to extend their survival time, in contrast to the case of the small cell carcinoma.
The results described above showed a difference in biological predeterminism of malignancy between two types of carcinoma and suggested that a critical analysis must -be made before a choice of surgical means for treatment of the small cell anaplastic carcinoma of the lung.View full abstractDownload PDF (1109K) -
Nobuo Yamashita1974 Volume 14 Issue 2 Pages 79-82
Published: June 25, 1974
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSIn this paper the author tried to calculate sample sizes for clinical trials in lung cancer treatment results that the survival-time patterns of patients have lognormality using the Owen's noncentral t-distribution and given following tables.
The table la and lb are given the relation between the expected difference Δμ in logmean and the required sample sizes that should be included in each group of a clinical trial in lung cancer treatment results in oder to have a 90% (β=0.90), 70% (β=0.70) and 50% (β=0.50) probability detecting significant difference (!α=0.05, α=0.01) in results and covered any value of the difference ranging from 0.03 to 0.30 and any value of ranging from 0.30 to 0.50.View full abstractDownload PDF (331K) -
Ikuro Kimura, Taisuke Onoshi, Nobuo Ueda, Shozo Yasuhara, Tatsuo Watan ...1974 Volume 14 Issue 2 Pages 83-89
Published: June 25, 1974
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSSince few years ago, there are many reports that radiotherapy is preferable to surgery in the treatment of small cell anaplastic carcinoma of the lung. We report in this paper on two long-term survival cases of small cell anaplastic carcinoma of the lung treated with intensive chemotherapy. (One case was treated with a combination of radio and chemotherapy.) The two cases were administered with a cyclophos-phamide derivative, ifosfamide (Z4942) as an initial chemotherapeutic agent and carefully continued on combined chemotherapy of several anti-cancer agents for consolidation.
Consequently, both are still alive for about 17 months from the initial therapy and followed in our out clinic. It seems, at the present time, that the best treatment of small cell anaplastic carcinoma of the lung is combined therapy of radio-and chemotherapy.View full abstractDownload PDF (6207K) -
Masaji Maezawa, Jiro Mikami, [in Japanese]1974 Volume 14 Issue 2 Pages 91-97
Published: June 25, 1974
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSAn autopsy case of squamous cell carcinoma suspected of Thymus origin in man aged 65 is reported.
This case had continous infiltration of carcinoma to hert, sternum and precordial skin, and died of cardiac insufficiency.
Autopsy showed only squamous cell Carcinoma occupying all tumor.
About histogenesis of squamous cell carcinoma of thymus origin we considered not only Hassall's corpuscle, but stray germ.View full abstractDownload PDF (3916K) -
Y. Kosakai, [in Japanese], [in Japanese], [in Japanese], [in Japanese] ...1974 Volume 14 Issue 2 Pages 99-104
Published: June 25, 1974
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSA 64-year-old male was admitted with a complaint of fatigue. Roentgenograms revealed a tumor shadow in the left middle lung field. By left thoracotomy, the left lung was removed successfully, which included a hen-egg sized.tumor at the hilus of the upper lobe. Histological examination of the upper lobe revealed another guail-egg sized tumor located at the peripheral region and isolated from the original tumor. The former was a squamouscell carcinoma and the latter was a adenocarcinoma.View full abstractDownload PDF (5410K) -
K. Furuse, M. Fukuoka, Y. Kusunoki, O. Miyamoto, K. Hojyo, T. Mitsuhas ...1974 Volume 14 Issue 2 Pages 105-112
Published: June 25, 1974
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSA 59-year-old man was hospitalized complaining of pain in chest and shoulder with some weightloss of two months' duration. Physical examination revealed dullness to percussion and decreased breath sounds in right lower lung field. Chest roentgenograms showed the multiple nodular densitres in the right hemithorax and irregularly thickened pleura extended over the right hemidiaphragm. Laminograms demonstrated these tumor masses were in periphery with extrapulmonary nature or entrapped in the interlobar fissure. The aspiration biopsy of mass was read as adenocarcinoma and showed the negative alcian Blue-PAS reaction. The patient became progressively weaker and died 4 months after admission. At antopsy, entire right pleural space was involved with yellow-white, fleshy tumor tissue, most severely involved in the diaphragmatic and costal surface of the lower lobe. On cut-section, there was a large semispherical tumor mass on the diaphragmatic surface and spread of the tumor involved the costal, diaphragmatic and interlobar pleura. The diaphragm had been penetrated, and tumor was present over the peritoneum and especially over the omentum. Microscopic examination showed the characteristic apperance of mesothelioma as described elsewhere. There were areas shown glandnlar, tubular or tubulopapillary pattern with well-defined epithelial cells that graded gradually fibrosarcomatous areas.View full abstractDownload PDF (5262K) -
Takehiro Naruse, Kozo Suzuki, Katsutoshi Sugiura, Masanori Kurashina, ...1974 Volume 14 Issue 2 Pages 113-119
Published: June 25, 1974
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSA 44 year-old man admitted for the evaluation of nausea and anorexia of four weeks' duration, and was diagnosed as having bronchogenic carcinoma with the syndrome of inappropriate secretion of antidiuretic hormone.
The tumor tissue obtained at autopsy had a significant level of antidiuretic hormone like activity.
Histological diagnosis was oat cell carcinoma, and electron microscopic study showed secretory granule-like structure in the cytoplasma of tumor cells.View full abstractDownload PDF (3574K) -
1974 Volume 14 Issue 2 Pages 121-122
Published: June 25, 1974
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSDownload PDF (187K) -
1974 Volume 14 Issue 2 Pages 123-136
Published: June 25, 1974
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSDownload PDF (2076K)
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