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Volume 15 (1975)
- Issue 4 Pages 277-
- Issue 3 Pages 159-
- Issue 2 Pages 89-
- Issue 1 Pages 1-
Volume 15, Issue 4
Displaying 1-8 of 8 articles from this issue
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Results of Field StudyK. Yoshimura, N. Yamashita, S. Ishikawa, A. Suzuki, T. Naruke1975 Volume 15 Issue 4 Pages 277-287
Published: December 10, 1975
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSCase records of histologically proven 1, 827 patients with lung cancer were submitted for analysis for the purpose of the establishment of TNM staging on a basis of a prospective field study which was carried out cooperatively at 107 participating institutions in Japan during the period 1967 to 1969.
An analysis of 1, 827 cases according to the existing TNM staging showed validity of the system. Whereas, when 1, 014 cases of stage 111 were divided into two groups; 450 cases with intrathoracic spread and 564 M1 cases, there noted definite statistical difference (P<0.001) between two groups. It is, therefore, considered that M1 group should be separated from the existing stage III and stage IV should be designated as a new stage.
As to the ranking of T1N1M0, wheather it would be in stage I or in stage II, was seemed justifiable to put it into stage II was our impression.View full abstractDownload PDF (1170K) -
Ikuro Kimura, Taisuke Onoshi, Shozo Yasuhara, Motoharu Sugiyama, Tatsu ...1975 Volume 15 Issue 4 Pages 289-294
Published: December 10, 1975
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSA treatment schedule combining 5 fluorouracil, vincristine, bleomycin, cyclo phosphamide and mitomycin C (FOBEM) was administered to advanced lung cancer patients. 5 Fluorouracil (250mg) was administered every other day. Vincristine (1mg), bleomycin (15mg), cyclophosphamide (400mg) and mitomycin C (4mg) were each administered once a week for six consecutive weeks. Fourteen of 49 (28.6%) evaluated patients had significant tumor regression. Included among the 14 were two patients with small cell carcinoma with complete regression.
Histological classification indicated: 17.6%, adenocarcinoma; 35.3%, squamous cell carcinoma; and 57.0%, anaplastic carcinoma; 12.5% of patients were diagnosed cytologically or clinically. Patients responding to FOBEM therapy survived about two times longer after initiation of chemotherapy than non-responders, and the survival of patients treated with FOBEM therapy was slightly longer than those administered single drugs or a two drug combination. In aged patients pulmonary impairment with bleomycin was the major dose limiting factor instead of mild myelosuppressive toxicity, and the cumulative pulmonary toxicity necessitated the reduction of this drug. Combination chemotherapy with 5 fluorouracil, vincristine, bleomycin, cyclophosphamide and mitomycin C warrants further investigation in the management of small cell and squamous cell carcinoma of the lung.View full abstractDownload PDF (611K) -
Eiji Nakagawa, Hajime Nakata, Isao Watanabe, Keiichi Matsuura1975 Volume 15 Issue 4 Pages 295-302
Published: December 10, 1975
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSBronchograms of 114 cases of lung cancers were reviewed. Findings on bron chograms were evaluated in relation to the order of the abnormal bronchus and the adequateness of the technique. Sixty Four% of the cases showed obstruction and 18.4% had stenosis. There were 12.3% without recognizable abnormality. As for the diagnostic ability according to the order of bronchus, 97% of the cases originating up to 3rd order bronchus and 68% of the lesions in 4th arid 5th order bronchus were diagnosable. When located in the 6th order bronchus or more peripherally, the diagnosis was possible only in 25% of cases.
In total the diagnosis with bronchography was possible in 81% of the cases. In 19% it was not possible due to the presence of equivocal findings alone or the absence of recognizable abnormality.View full abstractDownload PDF (6282K) -
Toshiro Kumasaka1975 Volume 15 Issue 4 Pages 303-317
Published: December 10, 1975
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSAn immunological study of the humoral antibody, immuneglobulin and com plement, immunocapacity of 180 cases of primary lung cancer was made. In many of them, the immuneglobulin IgG IgA complement titer (CHSO) and component C4 values were high. Using the fluorescein antibody technique, the localization of immuneglobulin IgG and complement components C4 C3 is seen in lung cancer tissue. This perhaps indicates the resistence of the host to cancer. This study shows that the functional ability of humoral antibody is well preserved even in the end stage and that thus humoral antibody play an extremely important part in cancer immunology.View full abstractDownload PDF (8642K) -
Ryosuke Ono, Shigeto Ikeda1975 Volume 15 Issue 4 Pages 319-330
Published: December 10, 1975
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSIn the bronchography of the lung cancer case, special findings of a certain extent call be obtained according to the deformed or variated findings, how large the lesion is, the localization of the lesion in the bronchus, and the type of histological findings. It is supposedly possible to obtain the histological diagnosis through the bronchographic findings of lung cancer with the histo-pathological background of bronchographic findings of 318 localized lung cancer cases.View full abstractDownload PDF (9501K) -
H. Sato, M. Fujiwara, K. Hashimoto, M. Oshibe1975 Volume 15 Issue 4 Pages 331-335
Published: December 10, 1975
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSA 70 aged man with a habit of heavy smoking underwent the left upper lobectomy under the diagnosis histologial examination on the main tumor situated in periphery of S1+2 showed undifferentiated adenocarcinoma.
Following the histological examination on the epithelium of B1+2b, early invasive cancer (epidermoid carcinoma) was found.
Detailed examintions were made histologically on the epithelium in the vicinity of early cancer with special reference to the histgenesis of lung cancer.View full abstractDownload PDF (3023K) -
Masatoshi Ichiba, Keijiro Tsuji, [in Japanese], Yoshiaki Goya, Tadakiy ...1975 Volume 15 Issue 4 Pages 337-342
Published: December 10, 1975
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSFrom 1967 to 1974, 182 biopsies of lung cancer have been performed with the small-bore needle which we have designed for cytological diagnosis.
In 146 out of 182 cases of pulmonary carcinoma (80.2%) an accurate diagnosis was obtained by this method. We experienced one case of the development of a tumor in the needle tract, one year and seven months after performance of needle biopsy on an adenocarcinoma case with a 2×2cm nodular lesion in the right S3, which was radically resected. At that time, of course, neither cancer invasion to the pleura, lymphnode metastasis nor hematogenous metastasis could be seen. This case of implantation of tumor cells in the needle tract out of 10 early stage lung cancer cases with nodular lesions less than 2cm in diameter, successfully diagnosed by needle biopsy and radically resected, indicates that needle biopsy method should be employed in certain cases, in which other diagnostic procedures failed to obtain an accurate diagnosis and also that some steps should be taken to prevent such compli cations, for example chest wall irradiation.View full abstractDownload PDF (5022K) -
1975 Volume 15 Issue 4 Pages 343-360
Published: December 10, 1975
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSDownload PDF (2528K)
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