Nippon Jibiinkoka Gakkai Kaiho
Online ISSN : 1883-0854
Print ISSN : 0030-6622
ISSN-L : 0030-6622
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Volume 118, Issue 2
Displaying 1-13 of 13 articles from this issue
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Review article
Original article
  • Prognosis of Papillary Thyroid Carcinoma with Local Invasion
    Koichiro Yamada, Shinzo Tanaka, Yasuyuki Hiratsuka, Yohei Kumabe, Yosh ...
    2015 Volume 118 Issue 2 Pages 115-122
    Published: February 20, 2015
    Released on J-STAGE: March 05, 2015
    DOIhttps://doi.org/10.3950/jibiinkoka.118.115
    JOURNAL FREE ACCESS
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    　Objective: The aim of this study was to detect prognostic factors in patients with locally advanced papillary thyroid carcinoma.
    　Patients: The study included 72 patients (T4a/T4b 72/0, N0/N1a/N1b 25/15/32, M0/M1 68/4, mean follow-up 8.1±4.4 years) who underwent initial surgical treatment at Osaka Red Cross Hospital between April 1993 and April 2011.
    　Results: Eleven patients died of PTC, 3 patients with recurrence died of unrelated disease and 10 patients are alive with recurrence. The overall 5-year survival rate was 88.3%, and the 10-year survival rate was 73.4%. The disease-specific 5-year survival rate was 91.4%, and the 10-year survival rate was 88.6%. The 5-year local control rate was 94.1%, and the 10-year local control rate was 85.4%. Patients with distant metastasis (M1), tracheal invasion and/or multiple organs invasion showed a significantly worse disease-specific survival rate based on a univariate analysis, which also revealed that tracheal invasion, laryngeal invasion, esophageal invasion and multiple organs invasion were risk factors linked to the development of distant metastasis during follow-up (recurrence as distant metastasis). The following were found to be clinically significant risk factors, based on the multivariate analysis among tracheal invasion, laryngeal invasion, esophageal invasion and recurrent laryngeal nerve invasion: Tracheal invasion was a risk factor for disease-specific survival, and tracheal invasion and laryngeal invasion were risk factors for recurrence as distant metastasis.
    　Conclusions: In this study, distant metastasis, multiple organs invasion, tracheal invasion and/or laryngeal invasion were shown to be higher risk factors.
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  • Spindle Cell Carcinoma of the Head and Neck: A Report of 6 Cases
    Mioko Matsuo, Fumihide Rikimaru, Yuichiro Higaki, Muneyuki Masuda
    2015 Volume 118 Issue 2 Pages 123-128
    Published: February 20, 2015
    Released on J-STAGE: March 05, 2015
    DOIhttps://doi.org/10.3950/jibiinkoka.118.123
    JOURNAL FREE ACCESS
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    　Spindle cell carcinoma of the head and neck is a rare neoplasm. We at Kyushu Cancer Center experienced 6 cases of spindle cell carcinoma which accounted for 0.9% of all cases of head and neck squamous cell carcinoma. These cases presented with the characteristic clinical presentation, such as a particular form (polypoid and exophytic) and difficulty of pathological diagnosis. For treatment, surgery was performed in the main, but in one case of hypopharyngeal cancer chemoradiotherapy was undertaken. Spindle cell carcinoma exhibits a poor prognosis, compared with the other squamous cell carcinomas. However for the moment, 4 of 6 cases are surviving, and disease free. We will require long-term monitoring of these cases.
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  • Closed Septorhinoplasty for Caudal Septum Deviation: A Japanese Rhinologic Perspective
    Satoru Kodama, Kaori Tateyama, Nozomi Nomi, Masashi Suzuki
    2015 Volume 118 Issue 2 Pages 129-134
    Published: February 20, 2015
    Released on J-STAGE: March 05, 2015
    DOIhttps://doi.org/10.3950/jibiinkoka.118.129
    JOURNAL FREE ACCESS
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    　Caudal septum deviation is one of the most difficult tasks in nasal surgeries even for the experienced surgeons. Correction of the deviated nose presents a challenge because frequently a functional as well as an aesthetic problem must be addressed. In patient with caudal septum deviation, a proper correction of the deviated septal cartilage is a critically important factor for surgical success. For successful correction of caudal septum deviation, the skill to precisely execute the surgical steps is required to alter and control the septum thorough a thorough understandings of nasal anatomy and physiology, accurate preoperative analysis and intraoperative diagnosis, together with an understanding of the physiology of cartilage and its healing.
    　The closed (endonasal) septorhinoplasty approach provides a wide surgical filed that enables the surgeon to implement various surgical procedures. For correction of the caudal septal strut, placement of a batten graft on the concave side after scoring incisions can also be used, resulting in successful correction of caudal deviation. A functional septorhinoplasty with the ultimate purpose of improving nasal obstruction is expected to develop from the Japanese rhinologic perspective. In the current study, closed septorhinoplasty proved to be one of the most effective methods for correcting caudal septum deviation.
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  • Prediction of Post-operative Lymph Node Metastasis with a Molecular Biological Test in Head and Neck Cancer
    Katsumasa Takahashi, Kyoko Nakajima, Masato Shino, Minoru Toyoda, Yuki ...
    2015 Volume 118 Issue 2 Pages 135-139
    Published: February 20, 2015
    Released on J-STAGE: March 05, 2015
    DOIhttps://doi.org/10.3950/jibiinkoka.118.135
    JOURNAL FREE ACCESS
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    　We assessed herein the post-operative lymph node metastasis in head and neck cancer, using the One-step nucleotide amplification (OSNA) method targeting matrix metalloproteinase 7 (MMP-7). Compared with the pathological test, the molecular biological test revealed more lymph node metastasis, resulting in poor prognosis. Six cases, of which the number of lymph node metastasis was the same between pathological and molecular biological test, survived. On the other hand, three of four cases, in which number of lymph node metastasis in the molecular biological test were larger than the pathological test, died from metastasis. We concluded that the pathological test underestimated metastasis, and OSNA with MMP-7 was useful for the prediction of post-operative lymph node metastasis.
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Final Lecture
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Lifelong learning for Board Certified Otorhinolaryngologist
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