The authors report 3 cases of suppurative meningitis caused by comprehensive resection of upper jaw cancer and a statistical observation of the nasal supprative meningitis was attempted.
In reviewing 28 cases of this disease reported in the literatures since 1956 in Japan comparing with before, the following facts are established:
1) The death-rate;
(a) Before the introduction of antibiotics: 91.4%
(b) After the introduction of antibiotics: 18.7%
I stage (1949-1952): 40%
II stage (1953-1955): 15%
III stage (1956-1961): 10.7%
(c) There is a significant difference in deathrate between spontaneous infection (33.3 %) and operative origin (0%) in our III stage.
2) The facts show that the advancement of antibiotica has brought wonderful changes for the treatments and prognosis of nasal meningitis.
3) The new disease named “postoperative repeated nasal meningitis” has been described in 8 cases since 1956 and the authors have discussed the statistical observation of this disease.
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