巻号一覧
13 巻, 1 号
選択された号の論文の5件中1～5を表示しています
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WALTER STAHL, SHINKICHI AKAO1964 年 13 巻 1 号 p. 1-6
発行日: 1964年
公開日: 2009/05/26
ジャーナル フリー1) Prior infection of mice with the low-virulence Beverley strain of Toxoplasma, after a period of 3 weks or more, protected mice against an otherwise lethal challenge with the highly virulent RH strain.
2) The "immune" mice exhibited only a slight and transient loss of weight following exposure to RH, and after a week's time, commonly developed ascites, but otherwise remained in good condition. In contrast, the nonimmune mice suffered a sharp and sustained loss of weight, symptoms of severe disease, and death within 5 days.
3) Chronically infected mice (Beverley for more than 5 months) on occasion reacted violently to challenge with RH, with the rapidity and nature of the reaction suggesting hypersensitivity.
4) Briefly discussed are the participation of humoral factors in the acquired immunity, and the persistence of RH trophozoites in the peritoneal exudate of immune mice.抄録全体を表示PDF形式でダウンロード (224K) -
ICHIRO NAKAYAMA1964 年 13 巻 1 号 p. 7-12
発行日: 1964年
公開日: 2009/05/26
ジャーナル フリー1) Mice were infected with a non-virulent strain of Toxoplasma gondii, and after a period of 6 weeks to allow an immunity to develop, were challenged with the virulent RH strain.
2) The immune mice were examined for the presence of viable RH organisms in the peritoneal exudate, blood, and brain.
3) The blood, with but one exception, proved negative. The peritoneal exudate revealed trophozoites up to 1 week after the challenge, but thereafter became negative. The brain however proved positive for up to 7 weeks after the challenge, the limit of the present observations.
4) The persistence of virulent organism in the brain appears to be due to its intracellular location. The immune response engendered by the initial infection seems to be able only to suppress the multiplication of the parasite, not to eradicate it.抄録全体を表示PDF形式でダウンロード (268K) -
CORRELATING FACTORS BETWEEN MESANGIAL CELL PROLIFERATION AND INCREASED PERMEABILITY OF THE GLOMERULAR CAPILLARY WALLSADAO KAWAMURA1964 年 13 巻 1 号 p. 13-31
発行日: 1964年
公開日: 2009/05/26
ジャーナル フリーIn order to investigate factors of the mesangial cell proliferation in acute and diffuse intramembranous-proliferative glomerulonephritis, rabbits were used for making cases of the basement membrane damaged groups by administrations of sublimate, trypsin and hyaluronidase and arteriolar spasm groups by adrenalin and noradrenalin. The renal specimen of each case was observed by light- and partially electron microscopy. In the former groups there were in the glomerulus damages of the basement membrane, mesangial matrix and cellular components, proteinous substance in Bowman's space and hyalin droplet degeneration in various degrees of tubular epithelia, while the mesangial cell did not proliferate and rather decreased in number. If any increased, they were very slight. On the contrary in the latter groups, arteriolar spasm groups, particularly in the noradrenalin series, diffuse or focal mesangial cell proliferation with slight increase of the mesangial matrix was observed. The increase of the mesangial cell wa also ascertained by calculating the number of nuclei in the glomerulus. This fact suggests that intraglomerular hypoxia due to arteriolar spasm might be one of the factors for the mesangial cell proliferation which has been left behind in recent studies of investigating the pathogenesis of "Masugi-nephritis."
The author wishes to express grateful appreciation to Prof. Dr. T. Kobayashi and Dr. H. Sakaguchi for their cordial instructions. He is also indebted to the many people who gave him advice and technical assistance.抄録全体を表示PDF形式でダウンロード (9191K) -
HISAO YAMAGUCHI1964 年 13 巻 1 号 p. 43-58
発行日: 1964年
公開日: 2009/05/26
ジャーナル フリーThe initial changes of inflammation consists of several kinds of local circulatory disturbances, whatever the causes are, such as exudation, sticking and emigration of leucocytes, as the fundamental phenomenae. However the mechanism of those phenomenae are still obscure, because of the difficulty of the method and the complexty of the changes with time.
The writer has studied the peripheral circulatory disturbances on living tissue and intended to understand the fundamental changes of which various stages of the inflammation, from exudation to granuloma formation, are consisted.抄録全体を表示PDF形式でダウンロード (699K) -
AIKO HIYAMA, AKIKO TAKINAMI, HIROKO NONOBE, YASUMASA MAJIMA1964 年 13 巻 1 号 p. 59-65
発行日: 1964年
公開日: 2009/05/26
ジャーナル フリーIf the yeast was added simultaneously when carotene and α-tocopherol were given to the rats deficient in vitamin A and E, the amount of vitamin A in the liver and kidney was more increased and also the weight was gained. And through further pursuits, we found it was Mn that accelerated the increase of vitamin A in the liver and kidney and the gains of the weight. Finally it became evident that it is Mn from the consequence of examining the factor of the increase of Vitamin A in yeast and weight gains.抄録全体を表示PDF形式でダウンロード (295K)
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