巻号一覧
14 巻, 1 号
選択された号の論文の5件中1～5を表示しています
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WALTER STAHL, HISAKICHI MATSUBAYASHI, SHINKICHI AKAO1965 年 14 巻 1 号 p. 1-10
発行日: 1965年
公開日: 2009/05/26
ジャーナル フリーThe administration of the purine antagonist 6-MP greatly alters the course of a Toxoplasma infection in mice. The pathogenesis of the disease, in terms of morbidity and mortality, is much more severe; cyst production occurs in greater numbers, and possibly somewhat earlier than in normal mice; many cysts are found gathered in clusters; and the mice do not develop an effective immunity against a challenge with the virulent RH strain. A consideration of the pathological and serological findings in the 6MP-treated mice suggests that suppression of the immune response to Toxoplasma was achieved, and that as a result of this suppression, the various changes in the course of the infection occurred. The host immune response, therefore, does not appear to be a prerequisite to the formation and development of the Toxoplasma cyst.抄録全体を表示PDF形式でダウンロード (2764K) -
TAKASHI HAYASHI, YOSHIO KARAHASHI, HIROSHI TAKEUCHI1965 年 14 巻 1 号 p. 13-18
発行日: 1965年
公開日: 2009/05/26
ジャーナル フリーThe substances which are shown in Figs. 1, 2 and 3 have strong action to produce seizure, when applied into cerebrospinal fluid of dogs. The seizure producing action of them are not owing to their common physiological function but seems to owe to their structure of bearing quaternary nitrogen.抄録全体を表示PDF形式でダウンロード (206K) -
TAKASHI HAYASHI, ROKURO SUHARA, HIROO TAKASHITA, KIYOSHI OHKAME1965 年 14 巻 1 号 p. 19-25
発行日: 1965年
公開日: 2009/05/26
ジャーナル フリーParotid saliva of man can be measured exactly by a suction cup method and the experiment of conditioned reflex in man can be easily carried out by a course of duration of 21-60 minutes every other days. Artificial conditioned reflex will be established by Pavlov's method in man, quite as the same way as in dogs, notwithstanding man has resting saliva.
Resting saliva can not be detected from the permanent fistula opened outside of dog's cheek, while dogs have resting saliva when a suction cup is attached on the orifice of parotid gland.
It was verified by experiments with dog that the resting saliva was a reflex saliva, of which receptor stimulation must be a special mechanical stimulus by the attachment of a suction cup, and of which reflex centre was located at the gyrus coronarius, which corresponded to the face area of the anterior central gyrus in human cerebral cortex.抄録全体を表示PDF形式でダウンロード (1334K) -
YUJI SUEYOSHI, AKIHIKO KATO1965 年 14 巻 1 号 p. 27-35
発行日: 1965年
公開日: 2009/05/26
ジャーナル フリーThe influences of endocrines of hypophysis, adrenal cortex, thyroid, pancreas, and gonads were scrutinized in the albino rat. Results are summarized as follows:
1) When the fat content in diet was 20, 30, and 40%, the amount of body fat was 16.4, 20.2, and 16.2%, respectively. In subsequent experiments, therefore, diet containing 20% of fat was used and the amount of body fat more than 20% was judged to be increased.
2) ACTH was injected in doses of 1, 2, 3, and 5mg daily and the amount of body fat was maximal (23.6%) with 2mg of ACTH.
3) Cortisone was injected in doses of 0.5, 1, 2, and 3mg daily, and no increase in the body fat was noted in either case. It is indicated that the increase in body fat upon injection of ACTH is not due to augmented secretion of cortisone.
4) Thyradin, a thyroid preparation, was injected in doses of 0.1, 0.3, 0.4, 0.5, and 1ml. The result shows that the body fat was maximal (27.3%) when 0.4ml of Thyradin was injected. From the result in this experiment, it may be thought that the increase in amount of body fat upon injection of ACTH is due to augmentation of thyroid secretion.
5) Alloxan was injected in doses of 4, 6, 8, and 10mg, and the body fat was maximal (26.5%) upon injection of 6mg of alloxan, when the blood sugar level was 140-155mg per 100ml and the animal had no glucosuria.
6) Uni- and bilateral orchiectomy and ovariectomy resulted in the amount of body fat of 22-23%.
7) Neither of combinations of ACTH (2mg) and Thyradin (0.4ml), ACTH (2mg) and alloxan (6mg), Thyradin (0.4ml) and alloxan (6mg) injections, uni- or bilateral orchiectomy or ovariectomy and alloxan (6mg) injection, and ACTH (2mg), Thyradin (0.4ml) and alloxan (6mg) injections could produce increase in the body fat more than that produced by application of each one of the above treatments.
8) From the above results, it is concluded that the body fat increases when adequate amounts of ACTH, Thyradin, and alloxan are injected or when the gonads are exstirpated, and that the increase in body fat is the greatest with injection of either 0.4ml Thyradin or 6mg alloxan. In view of this, the increase in body fat should be the greatest in the moderate hyperthyroidal state or in the prediabetic state.
The combinations of the above treatments cannot raise the body fat above those levels obtained by each treatment alone.抄録全体を表示PDF形式でダウンロード (369K) -
AKIKAZU TAKADA, YUMIKO TAKADA, UTAKO OKAMOTO1965 年 14 巻 1 号 p. 37-43
発行日: 1965年
公開日: 2009/05/26
ジャーナル フリーPDF形式でダウンロード (265K)
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