巻号一覧
36 巻, 3 号
選択された号の論文の6件中1～6を表示しています
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根本 琢磨1987 年 36 巻 3 号 p. 256-261
発行日: 1987年
公開日: 2009/03/27
ジャーナル フリーThe most unique aspects of metastatic breast cancer is its hormonal respon-siveness, which can be exploited in the treatment of patients with this disease. Previously used modalitis such as adrenalectomy or hypophysectomy seem to have been replaced by nonsurgical management with aminoglutethimide. Another drug, tamoxifen, has now been widely accepted, in place of treatment with andro-gens, since it has a relatively low frequency of side effects. Progestins, such as medroxyprogesterone or megesterol, have also now established themselves as agents of endocrine therapy. Newer compounds are also now being tested. These would include leuprolide to achieve ovarian suppression; 4-hydroxyandrostene-dione, which is an aromatase inhibitor; buserelin, a luteinizing hormone releasing hormone agonist; and trilostane, a suppressor of adrenal steroidogenesis.抄録全体を表示PDF形式でダウンロード (274K) -
鶴見 清彦, 奥山 伸男1987 年 36 巻 3 号 p. 262-270
発行日: 1987年
公開日: 2009/08/24
ジャーナル フリーWe performed digital subtraction angiography (DSA) on 42 patients with breast diseases to investigate its efficiency. As a result we came to the following conclusions: 1. The sensitivity was well evaluated in intraarterial digital subtraction angiography (IA-DSA) of breast. 2. IA-DSA could diagnose difficult cases like cancer which had undergone augmentation mammoplasty, or like Paget's disease and others. 3. DSA was a safe examination method. 4. The sensitivity of IA-DSA of breast cancer is superior to intravenous digital subtraction angiography (IV-DSA).抄録全体を表示PDF形式でダウンロード (7689K) -
畠 亮, 橘 政昭, 出口 修宏, 馬場 志郎, 実川 正道, 田崎 寛1987 年 36 巻 3 号 p. 271-283
発行日: 1987年
公開日: 2009/03/27
ジャーナル フリーRenal autotransplantation and/or extracorporeal renal surgery has been done in 17 patients, including 10 with renovascular hypertension, 3 with arteriovenous malformation and 4 with bilateral or solitary renal cell carcinoma. Based on our institutional experiences, indication and limitation for the operation are dis-cussed, and 3 particular cases are presented. Our conclusion is that renal auto-transplantation and extracorporeal reconstruction can provide the best solution for selected renal problems not correctable by conventional methods, although actual number of such cases is thought to be limited.抄録全体を表示PDF形式でダウンロード (4263K) -
村上 博1987 年 36 巻 3 号 p. 284-297
発行日: 1987年
公開日: 2009/03/27
ジャーナル フリーWe have developed a new solid phase enzyme immunoassay (EIA) for detec-tion of anti-phospholipid antibodies in sera and platelet eluates from patients with idiopathic thrombocytopenic purpura (ITP). Antibodies against cardiolipin (CAR), phosphatidylinositol (PI) and phosphatidylserine (PS), not against phos-phatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidic acid (PA) and sphyngomyelin (SM) were frequently found in the ITP patients' sera. Among 69 ITP patients examined, IgG class antibodies against CAR, PI and PS were de-tected in 12, 10 and 9 patients and IgM class antibodies in 16, 18 and 13 patients, respectively. When platelet eluates were analysed instead of sera, anti-phos-pholipid antibodies in IgG class were detected in 14 cases out of 58 patients (anti-CAR 4, anti-PI 13 and anti-PS 5), while the antibodies of IgM class were found in only one case. Although severe thrombocytopenia was found in one ITP patient with the exceptionally high titer of anti-phospholipid antibody, there were no clear correlation between the platelet counts and the titers of anti-phospholipid antibodies in platelet eluates. Thus, it is suggested that anti-phospholipid anti-bodies do not play a major role in pathogenesis of thrombocytopenia in spite of such a high incidence. There were no distinct differences in clinical and labora-tory features between cases with and without anti-phospholipid antibodies. How-ever, it was of great interest that 2 ITP patients with high titers of antibodies against all three phospholipids (CAR, PI and PS) presented unique complications such as deep vein thrombosis and lupus anticoagulant, a risk factor for thrombosis.抄録全体を表示PDF形式でダウンロード (506K) -
堀田 昌宏, 佐藤 吉壮, 岩田 敏, 山下 直哉, 砂川 慶介, 老川 忠雄, 田中 隆一郎, 渡辺 幸一, 高山 博夫, 矢島 昌子, ...1987 年 36 巻 3 号 p. 298-314
発行日: 1987年
公開日: 2009/03/27
ジャーナル フリーWe investigated the effects of administration of Bifidobacterium preparations and commercially available Bifidus Yogurt on infantile intractable diarrhea. Fifteen patients with intractable diarrhea were treated from 1982 to 1985. These patients (11 boys and 4 girls) ranged in age from 1 month to 15 years (mean 2.5 years) and received antibiotic therapy for the treatment of such diseases as septicemia and respiratory tract infections. During treatment, waterly diarrhea appeared and lasted for 1 to 10 weeks (mean 25 days) with deterioration of the general condition. Conservative therapy such as diet control, infusion and drug therapy could not cure the diarrhea. The antibiotics used included cephems, penicillins and aminoglycocides. In most cases, abnormal microflora was observed: Candida or Enterococcus often predominated with a marked decrease of anaerobes and aerobes in the stool flora. During the disease, we could not detect any pathogens or toxins responsible for the diarrhea. In all patients, the stool frequency and appearance were dramatically improved within 3 to 7 days after oral administration of Bifidobacterium preparations of bifidus yogurt. The intestinal microflora of all subjects also became normal with predominance of resident Bifidobacterium or administered B. breve.抄録全体を表示PDF形式でダウンロード (641K) -
廣谷 隆, 前中 由己, 山本 修三, 小林 紘一1987 年 36 巻 3 号 p. 315-320
発行日: 1987年
公開日: 2009/03/27
ジャーナル フリーWe experienced a case of permeability pulmonary edema (ARDS) caused by massive inhalation of oxides of nitrogen. Using a flow-directed pulmonary artery catheter (Swan-Ganz), we monitored the systemic and pulmonary circula-tion and searched for evidence of pulmonary microembolism by carrying out balloon-occluded pulmonary angiography (BOPA) at the bed-side. Then we observed coagulation, disorders, which may be found at a high rate of incidence in ARDS, and it is interesting to note that these disorders occurred during the same period as the appearance of microemboli in BOPA. We carried out peep respiratory management at 5-10cm H2O with a respirator. Massive administration of methylprednisolone, and heparin administration were carried out. The patient was disconnected from the respirator on the tenth day, and he was discharged about one month after injury.抄録全体を表示PDF形式でダウンロード (1142K)
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