The Keio Journal of Medicine
Online ISSN : 1880-1293
Print ISSN : 0022-9717
ISSN-L : 0022-9717
23 巻, 3 号
選択された号の論文の4件中1~4を表示しています
  • SADAYOSHI SHIGETA
    1974 年 23 巻 3 号 p. 101-114
    発行日: 1974年
    公開日: 2009/03/27
    ジャーナル フリー
    Analysis of the factors which influenced the work load in handwriting were studied using the new apparatus for simultaneous measurement of grip and pen-point pressures developed by the author. Thickness of the pen holder was shown to be a factor which influenced the work load, and diameter of pen holder for minimum load was determined. Nature of the pen-point was also one of the factors, and it was shown that the ball-point pen gave the greatest load and felt-point pen gave the smallest load in three kinds of pen-points; ball-point pen, felt-tip pen and pencil. Number of copies also influenced the load to the upper extremities, and taking more than three copies gave excess work load to female workers.
  • II. ANALYSIS BY HIGH SPEED CAMERA IN TWO DIMENTIONAL EYE MODEL
    TOYOMI FUJINO, CHITORU SUGIMOTO, SADAO TAJIMA, YOSHIHIRO MORIBE, TAKES ...
    1974 年 23 巻 3 号 p. 115-124
    発行日: 1974年
    公開日: 2009/03/27
    ジャーナル フリー
    An analysis of 3 kinds impact tests by the high speed camera in two dimentional eye model; the impact to the eyeball alone, the impact to the infraorbital margin, and the impact to the eyeball and the infraorbital margin, showed that the primary factor of the orbital floor fracture was the buckling force of the orbital floor, but not the increased hydraulic pressure of the orbital contents. This is a new theory for the mechanism of the orbital blowout fracture and is against the present accepted theory by Smith.
  • KOJI FUKUSHIMA, SHIGESHI TOYOSHIMA
    1974 年 23 巻 3 号 p. 125-136
    発行日: 1974年
    公開日: 2009/03/27
    ジャーナル フリー
    The influence of anti-influenza virus drugs on the neuraminidase activity with three influenza virus strains was examined.
    When the allantoic fluid infected with influenza virus strains (A0/PR8, A2/Adachi and B/Lee) was treated with 1-adamantanamine hydrochloride (amantadine), the neuraminidase activity was significantly enhanced in all three influenza virus strains. The B/Lee strain exhibited the highest enhancement of neuraminidase activity after 1-adamantanamine hydrochloride treatment.
    When purified virus, enzyme source, was treated with various concentrations of 1-adamantanamine hydrochloride, the enhancement of neuraminidase activity with A0/PR8 strain was observed even at a lower concentration (0.1-400 μg/ml) and the activity further increased with increasing concentration of the drug and reached a plateau at the level of 600-1200 μg/ml. On the other hand, the enhancement of neuraminidase activity with the A2/Adachi strain was maximum at about 1 μg/ml of 1-adamantanamine hydrochloride.
    Treatment with isoquinoline derivatives resulted in the enhancement of neuraminidase activity with the A0/PR8 and A2/Adachi strains at a lower concentration, but at a higher concentration, one of the isoquinoline derivatives, UK 2371-01, presented an inhibitory effect.
    Our results suggest that the enhancement of neuraminidase activity with the influenza viruses may be a converse action to viral inhibitory activity of anti-influenza virus drugs.
  • TOYOMI FUJINO
    1974 年 23 巻 3 号 p. 137-163
    発行日: 1974年
    公開日: 2009/03/27
    ジャーナル フリー
    The distant transfer of the free skin flap by microvascular anastomosis opens a new era in reconstructive plastic surgery and herein the author's personal experiences regarding to the microvascular surgery are described in details in the following subjects; introduction, concept of microsurgery, microvascular instruments, fundamental techniques of microvascular anastomosis, experimental study in dogs, one staged transfer of free skin flap in clinical cases, and advantages and disadvantages of microvascular transfer of skin flap.
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