The Keio Journal of Medicine
Online ISSN : 1880-1293
Print ISSN : 0022-9717
ISSN-L : 0022-9717
29 巻, 3 号
選択された号の論文の4件中1~4を表示しています
  • TOSHIHIKO ARAI, SADAO KOMATSU, YOKO KOMATSU
    1980 年 29 巻 3 号 p. 99-109
    発行日: 1980年
    公開日: 2009/03/27
    ジャーナル フリー
    We surveyed antibiotic resistant E. coli strains isolated in the clinical laboratories of various hospitals around Tokyo area and their conjugative R plasmids in 1978. Incidences of antibiotic resistant strains in the clinically isolated strains were about 60% in every hospitals and materials except those in feces, where the strains contained those collected from healthy human. Frequencies of the strains resistant to sulfonamides, tetracycline, streptomycin, ampicillin, chloramphenicol and kanamycin in all resistant strains were 71, 54, 63, 52, 44 and 19%, respectively. About 40% of the resistant strains had conjugative R plasmids. Frequencies of the conjugative R plasmids carrying resistances to tetracycline, streptomycin, ampicillin, chloramphenicol, sulfonamides and kanamycin were 56, 54, 46, 40, 34 and 22%, respectively. Predominance of the single drug resistant conjugative R plasmids, especially ampicillin resistant R plasmids was new tendency of the recently isolated E. coli strains. Twenty-six % of these R plasmids were classified into Fi+ (F) type. Incidences of Fi+ (F) type R plasmids were higher in the strains isolated from pus and lower in those from feces.
  • TOSHIHIKO ARAI, SADAO KOMATSU, YOKO KOMATSU
    1980 年 29 巻 3 号 p. 111-124
    発行日: 1980年
    公開日: 2009/03/27
    ジャーナル フリー
    We surveyed the adhesive, enterotoxigenic, hemolytic, colicin producing, cell-invasive, capsule forming, special surface antigen producing and actively iron incorporating strains in the Escherichia coli strains isolated from various clinical materials of general hospitals in dfferent districts. Incidences of these bioactive strains were different depending on the organs isolated but not so different in various hospitals. The differences of distributions of the strains carrying these various activities suggested that human cell specific adhesins and hemolysins gave advantages to the strains to reside in re-spiratory tract, that capsules helped the strains to survive in pustular foci, and that the surface antigens common to enteropathogenic bacteria helped the strains to grow in intestine and respiratory tract. Colicin productions and active incorporations of iron could give advantages to grow over other bacteria but gave no preferences to the special organs. Enterotoxigenic and cell invasive strains were found to be very rare in the clinically isolated strains.
  • TOSHIHIKO ARAI, KATOMI YAO-SUGAWARA, TAKASHI AOKI
    1980 年 29 巻 3 号 p. 125-132
    発行日: 1980年
    公開日: 2009/03/27
    ジャーナル フリー
    We examined the stability of various R plasmids in Vivrio cholerae, and found that many of the R plasmids detected in the bacteria isolated from human and domestic animals were very unstable in this bacterium, but a few of them as well as most of the R plasmids detected in the bacteria from marine as well as fresh water fish were stably maintained in this bacterium. Chloramphenicol, tetracycline and sulfonamides resistances mediated by these R plasmids were lower in V. cholerae than in Escherichia coli, streptomycin resistance mediated by these R plasmids was far higher in V. cholerae than in E. coli, and ampicillin resistance mediated by these R plasmids was almost same in both V. cholerae and E. coli.
  • MASAO NAGANO, HIROMASA SEKIGUCHI, TOSHIYUKI SHIGEMATSU, MICHINOSUKE AM ...
    1980 年 29 巻 3 号 p. 133-140
    発行日: 1980年
    公開日: 2009/03/27
    ジャーナル フリー
    By means of a newly developed sensitive pressure transducer connected to the endotracheal tube of the anesthetized patient, small changes of air pressure through the airway caused by cardiogenic mechanical oscillations were recorded during apneic condition induced by succinylcholine chloride. This pressure recording was tentatively termed as an intratracheal cardio-gram (ITCG).
    This transducer has a high resonant frequency enough for precise record-ing of spike waves in ITCG caused by valvular movements.
    Some of the parameters calculated from the spike waves in ITCG with reference to ECG; i.e. QC, BC, QB, and QB/BC, were compared with such indices of systolic time intervals (STI) simultaneously obtained by the con-ventional non-invasive methods as EMS, LVET, PEP, and PEP/LVET. There are highly significant correlations between the corresponding param-eters and derivatives of the conventional and new methods. This technique is expected to be useful tool in assessing cardiac function during endotracheal intubation.
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