The Keio Journal of Medicine
Online ISSN : 1880-1293
Print ISSN : 0022-9717
ISSN-L : 0022-9717
18 巻, 1 号
選択された号の論文の5件中1~5を表示しています
  • YUJI SUEYOSHI
    1969 年 18 巻 1 号 p. 1-12
    発行日: 1969年
    公開日: 2009/05/26
    ジャーナル フリー
    Experiments were performed on the esterifying activity of cholesterol-esterases from liver, pancreas, intestinal mucosa, and adrenal glands. The activity was expressed as percent esterification of cholesterol added to the medium.
  • KEIKO HATA, SUMIKO NAGAO, FUMIE NAKAMURA, YASUMASA MAJIMA
    1969 年 18 巻 1 号 p. 13-20
    発行日: 1969年
    公開日: 2009/05/26
    ジャーナル フリー
    The specific activities of fatty acid of cholesterol esters in the liver and the serum of rats which were administered C14 palmitic acid and cholesterol or C14 linoleic acid and cholesterol after 2 weeks feeding with the diet containing cholesterol palmitic acid or cholesterol linoleic acid were determined, and the specific activities of cholesterols in the livers and the sera of rats which wereadministered C14 glucose, C14 palmitic acid, C14 oleic acid or C14 linoleic acid for 3 days after 2 or 4 weeks of feeding with the diet containing palmitic acid, oleic acid or linoleic acid were also determined. There were no differences of the rates of degradation of cholesterol between rats administered palmitic acid and that administered linoleic acid. The synthesis of cholesterol was promoted in course of day by the administration of palmitic acid or oleic acid, but those from linoleic acid and glucose did not increase.
    From these results, it is considered that the hypercholesteremia by the ingestion of the large amount of saturated fatty acids is mainly due to the promotion of the cholesterol synthesis from saturated fatty acids and the invariability of the serum cholesterol by the ingestion of polyunsaturated fatty acids (to maintain the normal level) is mainly due to that the cholesterol synthesis from linoleic acid does not increase.
  • HIROAKI KAHYO
    1969 年 18 巻 1 号 p. 21-33
    発行日: 1969年
    公開日: 2009/05/26
    ジャーナル フリー
    With the purpose of discovering the indicators usable for measurement of the levels of health of a small community from among the pre-existing statistical data, the physical statistical data of schoolchildren were selected from the statistics for school health and their usability as health indicators of a given community was examined.
    1) The field surveyed was Hadano City, Kanagawa Pref., (a population of 50, 000-60, 000). Using the integrated physical values stated in the previous report, measurement of the levels of health was conducted according to seven school districts in the same city. The results were examined in comparison with the results of the measurement of health levels by the eight health indicators based on the vital statistics. Among the eight health indicators which are generally used, the rate of deliveries in institution corresponded with the integrated physical values (especially height and body weight).
    2) In view of the relation of the results of the integrated physical values with the environmental conditions observed according to small districts, it was observed that the relative difference seen in the integrated physical values (particularly, height) was closely associated with the progressing stage of urbanization of the pertinent district.
  • TAKASHI TOMITA, MASAKI MORIYAMA, TOHRU MINE, MASAHIRO MIZUKAMI, HIROSH ...
    1969 年 18 巻 1 号 p. 35-45
    発行日: 1969年
    公開日: 2010/01/19
    ジャーナル フリー
    We reported two cases of the occlusion of middle cerebral artery which took satisfactory recovery by antipodal therapeutic procedures. First case was verified a complete revisualization of the occluded artery by conservative procedure with a kinin antagonist and 2nd case recovered by emergency internal and external decompression craniectomy just before the brain stem herniation.
  • TAKEJI NISHIKAWA
    1969 年 18 巻 1 号 p. 47-57
    発行日: 1969年
    公開日: 2009/05/26
    ジャーナル フリー
    There was no macroscopic or microscopic ulcer found in the stomach of ICR germ-free mice even when they were treated with relatively large doses of cortisone. When the germ-free mice were orally inoculated with C. albicans combined with subcutaneous administration of cortisone acetate with the doses of more than 5mg, shallow ulcer developed at the site of the junction between forestomach and glandularstomach in the majority of the cases. In the base of ulcer, candida showed not only hyphal form but also other various forms. Polymorphonuclear leukocytic infiltration with candida organisms was observed at the site of the junction of the forestomach and glandularstomach shortly after oral inoculation with C. albicans. It was considered that the development of ulcer was secondary to the affection of candida. These results indicate that the lowering of the host resistance play an important role on the developement of systemic candida infection.
feedback
Top