巻号一覧
25 巻, 2 号
選択された号の論文の5件中1～5を表示しています
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Part ISEIICHI AKIYAMA, JIRO TSUBOUCHI, KIICHIRO KUROSAWA1976 年 25 巻 2 号 p. 55-65
発行日: 1976年
公開日: 2009/03/27
ジャーナル フリーIt is commonly believed that the bacteriolytic or biochemical actions of bacteriophage are performed upon specific bacterial species. The possibility of bacteriophage actions on cancer cell, accordingly, seems not to be generally accepted at present. However, recently some authors have reported on the relation between bacteriophage and cell of highly differentiated organism. We surmised that it was necessary to make clear whether a certain phage may act upon the cancer cell or not. The phage used was Escherichia coli 06 and was injected repeatedly into the peritoneal cavity of mouse with Ehrlich's ascites tumor. The light and electron-microscopic observation revealed that intact phage particles were found in cancer cells especially in their cytoplasm where remarkable changes had occurred. The particles were located mainly within the smooth and rough surfaced endoplasmic reticulum.抄録全体を表示PDF形式でダウンロード (14124K) -
ITS SIGNIFICANCE IN RELATIONSHIP TO THE PALMAR ERYTHEMA AND TO THE VASCULAR SPIDERKOICHIRO KAMO1976 年 25 巻 2 号 p. 67-72
発行日: 1976年
公開日: 2009/03/27
ジャーナル フリーThe significance of the paper money skin is not clearly defined. Re-cently, two cases of the paper money skin as a skin change due to cirrhosis of the liver have been experienced.
The importance of the paper money skin is emphasized as a relatively specific sign of chronic liver diseases, especially of cirrhosis of the liver.抄録全体を表示PDF形式でダウンロード (1746K) -
KENZABURO TSUCHIYA, MINORU SUGITA, YUKIO SEKI1976 年 25 巻 2 号 p. 73-82
発行日: 1976年
公開日: 2009/03/27
ジャーナル フリーAlthough biological half-times of metals in an organ or the total body have been calculated in animal experiments in which a metal is administered and the reduction of the metal in the organ or total body measured, the present study attempts to estimate biological half-times of cadmium in the organs and total body of humans by the observed accumulation of cadmium according to age. In this study the biological half-time of cadmium in the organs, par- ticularly the kidney, and in the total body, were estimated to be much longer than results obtained from animal experiments. However, biological half-times estimated in this study vary greatly according to the amount of daily exposure to cadmium, sex, age, and certain other factors. The validity of the method used in this study needs further verification.抄録全体を表示PDF形式でダウンロード (403K) -
KENZABURO TSUCHIYA, YUKIO SEKI, MINORU SUGITA1976 年 25 巻 2 号 p. 83-90
発行日: 1976年
公開日: 2009/03/27
ジャーナル フリーIn this study cadmium concentrations in several organs of more than 100 cadavers were measured in order to estimate the total body burden of cadmium by age. Six hundred urine samples from inhabitants of Tokyo of various age groups were collected in order to measure cadmium concentrations to observe if urinary cadmium concentration reflects the total body burden. The average renal cadmium concentration in the age group 40-49 years reached about 200μg/g (20mg net weight in the kidneys). However, individual variation was very great. The total body burden of cadmium was calculated to be about 45mg in the age groups 30-59 years. In general, cadmium concentrations in the organs and the total body increased with age, leveling off at about 60 years of age. The average cadmium concentration in urine was 1.7μg/l in all age groups, increasing by age and showing a pattern similar to that of cadmium concentrations in the total body according to age, and it was shown that on a group basis, cadmium in urine of the Japanese people reflected the total body burden of cadmium.抄録全体を表示PDF形式でダウンロード (311K) -
KENZABURO TSUCHIYA, YUKIO SEKI, MINORU SUGITA1976 年 25 巻 2 号 p. 91-100
発行日: 1976年
公開日: 2009/03/27
ジャーナル フリーThis study aims to establish a dose-response relationship in exposures to lead and cadmium. For lead, lead concentrations in blood and urine were used as indices of dose. Delta-ALA and coproporphyrin in urine were used as re-sponses. Policemen who were exposed to 0.5-1.0 μg/m3 as well as lead workers exposed to about 30 μg/m3 during working hours were subjects for the study. It was concluded that in a work environment in which workers are exposed to about 30 μg/m3 lead, blood lead concentration increased to above normal level without increase of delta amino-levulinic acid (ALA) in urine. Increase of delta-ALA in urine was noted when the blood lead concentration level exceeded 50 μg/100 ml. For cadmium, both blood and urinary concentrations of cadmium and protein in urine were used in order to discuss the dose-response relation-ship. The relationship between cadmium concentration in blood and in urine was one of logarithmic regression. Among workers exposed to cadmium fume, protein in urine increased when cadmium in urine exceeded 50 μg/l and cad-mium in blood exceeded 4-6 μg/100 ml.抄録全体を表示PDF形式でダウンロード (410K)
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