The Keio Journal of Medicine
Online ISSN : 1880-1293
Print ISSN : 0022-9717
ISSN-L : 0022-9717
33 巻, 3 号
選択された号の論文の5件中1~5を表示しています
  • HISAO TACHIBANA, ATSUO KOTO, YASUO FUKUUCHI, SHIN-ICHIRO EBIHARA, FUMI ...
    1984 年 33 巻 3 号 p. 119-125
    発行日: 1984年
    公開日: 2009/03/27
    ジャーナル フリー
    An 86-year-old Japanese man with caudato-pallido-nigral and cerebral degeneration is reported. The patient demonstrated parkinsonism and mental deterioration of slow progression and died 7 years after the onset. Necropsy disclosed severe neuronal loss and gliosis in the substantia nigra, globus pallidus and caudate nucleus, and frontotemporal cortical atrophy with myelin pallor of the white matter. This case could not be categorized within the current nosological entities of degeneration. Its nosological classification is discussed with particular regard to the pallido-nigral degeneration.
  • JUNICHIRO KUBOTA, TOYOMI FUJINO, CHITOH SUGIMOTO, TOHORU ABE
    1984 年 33 巻 3 号 p. 127-136
    発行日: 1984年
    公開日: 2009/03/27
    ジャーナル フリー
    The majority of people who have received the injections of the materials used in mammaplasty during the past thirty years have been admitted to the hospital with complaints of induration, redness, and/or pain of the injected areas.
    Since 1970 the relationship between the injected materials and later complications of 103 cases have been under observation.
    Induration of the injected areas has been observed in 90 of the 103 cases. Swelling, redness, and/or pain which recurred at intervals of several months to several years were observed in 100 of the one hundred-three patients, 18 lapsed into general malaise; seventeen had arthralgia and stiffness; 8 had high fever and 10 patients had lymphoadenopathy. Four cases had collagen disease like symptoms, i.e. tests for LE-cell, anti-nuclear anti-body, and anti-DNA antibody were all positive.
    Extirpation performed on 42 patients disclosed that 25 had injected silicone gel; 12 had injected paraffin oil; and 5 patients had undiagnosed materials. Seventeen of the forty-two cases were analysed by an infrared spectrum analysis. Nine showed medical grade silicone gel and 8 cases showed paraffin oil. In this follow-up study of 10 years, complete cure was not encountered in patients who developed systemic symptoms. We suspect that silicone induced adjuvant disease may occur in persons with a special disposition in immunoreaction.
  • SOICHIRO NOMURA, NOBUYUKI UKEI, JUN SHIMIZU, SHIROH SAKAIDA, TSUNEYUKI ...
    1984 年 33 巻 3 号 p. 137-142
    発行日: 1984年
    公開日: 2009/03/27
    ジャーナル フリー
    Imipramine (about 30mg/kg a day) was given to mice orally for 14 days. β-adrenergic receptor binding in the cerebral cortex, the Forced Swimming Test and the Open Field Test was examined sequentially. β-receptor binding decreased and the wheel turning behavior in the Forced Swimming Test increased with repeated dose of imipramine. The both parameters returned to the original level relatively rapidly after the termination of the drug. The locomotor activity in the Open Field Test did not change through the all experimental days. The relationship between behavioral and neurochemical changes was discussed.
  • TOSHIHIKO ARAI, SADAO KOMATSU, ATSUKO KUSAKABE
    1984 年 33 巻 3 号 p. 143-151
    発行日: 1984年
    公開日: 2009/03/27
    ジャーナル フリー
    We surveyed plasmid DNAs in the 40 naturally occurring strains of Bacteroides melaninogenicus and found that three strains had two different plasmids in these cells. A strain of subsp. intermedius had 1.4 and 1.9 Mdal plasmids and two strains of subsp. melaninogenicus had 1.4 and 2.2 Mdal plasmids. We failed to identify any genetic characters mediated by these plasmids. But, through this study, we found that strains of subsp. intermedius and melaninogenicus were not different in their antibiotic susceptibilities and bacteriocin productions, and that a few strains were resistant to ampicillin and erythromycin.
  • 1984 年 33 巻 3 号 p. 160
    発行日: 1984年
    公開日: 2009/03/27
    ジャーナル フリー
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