Albino rats maintained on a fat and pyridoxine deficient diet were divided into 2 groups. In the first group, 1-C
14-arachidonic acid and pyridoxine were given, and 1-C
14-arachidonic acid alone was given in the second group, to deter-mine the specific activity of fatty acid in liver phospholipid 24 hours later. In the result, dienoic fatty acid gave values twice as much as those of polyenoic fatty acid in each group. The change of arachidonic acid to linoleic acid in liver phospholipid in albino rats was thus demonstrated.
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