All issues
Volume 113, Issue 11
Displaying 1-6 of 6 articles from this issue
- |<
- <
- 1
- >
- >|
Review article
-
Keiji Tabuchi, Akira Hara2010 Volume 113 Issue 11 Pages 831-837
Published: 2010
Released on J-STAGE: May 28, 2011
JOURNAL FREE ACCESSThe effect of glucocorticoids on sensorineural hearing loss of sudden onset remains to be controversial although glucocorticoids have been used for treatment of sudden sensorineural hearing loss. We review recent findings about the effect of glucocorticoids on cochlear ischemic and acoustic injuries obtained from animal experiments.
Systemically administered glucocorticoids penetrate the blood-cochlear barrier well. Glucocorticoids ameliorated the cochlear ischemic and acoustic injuries at a relatively wide range of doses, and they protect cochlear hair cells in these types of injury. The therapeutic actions of glucocorticoids in cochlear injuries were considered to be mediated via both genomic and non-genomic pathways. Based on the results obtained in acoustic injury, therapeutic time window of glucocorticoids is considered to be short after the onset of injury. These findings obtained from animal experiments are important in considering clinical usage of glucocorticoids for the treatment of sensorineural hearing loss.View full abstractDownload PDF (515K)
Original article
-
Tomonori Terada, Nobuo Saeki, Nobuhiro Uwa, Kosuke Sagawa, Takeshi Moh ...2010 Volume 113 Issue 11 Pages 838-843
Published: 2010
Released on J-STAGE: May 28, 2011
JOURNAL FREE ACCESSFrom January 2000 to December 2008, we conducted voice rehabilitation using the Provox2® voice prosthesis in 40 total-laryngectomy subjects.
Of these, 36 attained restoration of 90.0%. Mean maximum phonation time (MPT) was 14.5s, ranging from 8 to 28s. MPT was not influenced by age, radiotherapy use, primary tumor site, or reconstructive surgery use.
Voice prosthesis replacement averaged 25 weeks (5.8 months), ranging from 9 to 74 weeks.
Complications occurred in 16 caces (40.0%), mainly granulation tissue formation and prosthesis-site infection, but also aspiration pneumonia, prosthesis-site salivary leakage, inability to replace the prosthesis, tracheomalacia, and foreign bodies in the trachea. Management rather than medical problems included cost, frequent hospital visits, and refusal or lack of motivation to use a prosthesis.
The Provox2® voice prosthesis speech provides a higher rate of speech restoration, longer phonatory time, and better intelligibility. Management problems, however, require that we work to understand subjects' living environments and family situations better for evaluating Provox2® voice prosthesis indication more effectively.View full abstractDownload PDF (388K) -
Jun Suzuki, Toshimitsu Kobayashi2010 Volume 113 Issue 11 Pages 844-850
Published: 2010
Released on J-STAGE: May 28, 2011
JOURNAL FREE ACCESSIntroduction: The Internet is widely used to find medical information. Facial nerve paralysis, with its numerous, varied diagnoses and broad field expertise in otorhinolaryngology and other departments, has triggered countless sites with widely varying quality and reliability. We clarified concerns on Internet-related information availability on facial nerve paralysis.
Methods: We reviewed information using Japanese and English search terms for “facial nerve paralysis, facial palsy” on Google Japan (GJ), Yahoo Japan! (YJ), and Google USA (GU), clarifying the top 50 Web sites.
Results: GJ and YJ search results showed few public institution Web sites, whereas those of commercial acupuncture and moxibustion practitioners accounted for about 40% of all the sites. GU sites generally described differential diagnoses well, with extensive, accurate information mainly developed by Western-medicine doctors rather than acupuncture and moxibustion practitioners.
Conclusions: The quality of facial nerve paralysis information on the Internet varies widely, with Web sites containing reliable, extensive information, especially those developed by public institutions, greatly lacking as of this writing.View full abstractDownload PDF (817K) -
Hiroshi Yamazaki, Yasushi Naito, Shogo Shinohara, Keizo Fujiwara, Masa ...2010 Volume 113 Issue 11 Pages 851-855
Published: 2010
Released on J-STAGE: May 28, 2011
JOURNAL FREE ACCESSMalignant external otitis (MEO) is a devastating external auditory canal infection usually occurring in the elderly with diabetes. MEO often progresses to potentially lethal skull base osteomyelitis (SBO) complications such as meningitis or multiple cranial nerve palsies. Poor vascularity in affected tissue due to diabetic microangiopathy and Pseudomonal infection is thought responsible for refractory infection. We conducted intraarterial antibiotic infusion (IA) in the external carotid artery of two subjects with intractable MEO deteriorating after long-term intravenous antibiotic administration with surgical debridement. IA raised the antibiotic concentration in infectious tissue. Clinical MEO manifestation was relieved just after starting IA, and IA therapy was followed by additional long-term intravenous and oral antibiotic administration, dramatically improving MEO while leaving only minimal infection at the skull base. These results demonstrate IA effectiveness in treating refractory MEO.View full abstractDownload PDF (1190K)
Educational lecture
-
[in Japanese]2010 Volume 113 Issue 11 Pages 862-865
Published: 2010
Released on J-STAGE: May 28, 2011
JOURNAL FREE ACCESSDownload PDF (542K)
Erratum
-
Kohei Nishida, Masayoshi Kobayashi, Hitomi Ogihara, Tetsu Takeo, Masak ...2010 Volume 113 Issue 11 Pages 872
Published: 2010
Released on J-STAGE: May 28, 2011
JOURNAL FREE ACCESS
- |<
- <
- 1
- >
- >|