The purpose of this study was to investigate the kinetics of Vco
2during incremental exercise. The subjects were 7 males, age 21-28 years, exercised at two steady state work loads (540 kpm/min, 810 kpm/min) and incremental work load which was increased stepwise by every 1 min from 180 kpm/min to exhaustion. The Vo
2and Vco
2during steady state exercise (4 to 5 min) were determined by the Douglas bag method and arterialized blood samples were taken for lactate (LA) analysis and blood gas analysis. The Vo
2, Vco
2, and blood lactate were also determined throughout the incremental exercise. At exhaustion, mixed venous Pco
2 (PVco
2) was determined by the CO
2rebreathing method.
1) The Vco
2values at rest and during steady state exercise were linearly related to the Vo
2values. When the regression line was compared with Vco
2during the incremental exercise on the same Vo
2, the Vco
2during the incremental exercise below the anaerobic threshold showed lower values.
2) The total sum of the difference in Vco
2between steady state and incremental exercise was defined as CO
2store. The calculated CO
2store and CO
2store per body weight were significantly related to PVco
2at exhaustion in incremental exercise, respectively (r=0.954, r=0.954) .
3) At work load below the anaerobic threshold, Vco
2was linearly related to Vo
2. If the Vco
2above the anaerobic threshold is estimated from Vo
2using the regression line obtained at work load below the anaerobic threshold, the estimated Vco
2will be lower than the measured Vco
2. The total sum of the difference in the Vco
2was defined as CO
2excess. The CO
2excess and the CO
2excess per body weight were significantly related to ΔLAmax (the difference between LA at 3rd min after exhastion and LA at exercise below the anaerobic threshold), respectively (r=0.870, r=0.930) .
4) HCO
3-calculated from blood gases (pH and Pco
2) was significantly related to LA (r=-0.902) . The increase of 1 mM/1 in LA was corresponding to the decrease of 0.843 mEq/l in HCO
3-.
5) From these results, it appeared that the expired Vco
2during the incremental exercise consisted of the stored Vco
2, the exceeded Vco
2, and the produced Vco
2 (Vco
2metabolically produced from Vo
2) .
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