Ukogi (Acanthopanax sieboldianum) leaves have been used as vegetables in the Yonezawa area of Yamagata Prefecture since the Edo period. The effects of ingesting ukogi leaves on intestinal fermentation and fecal excretion were investigated in rats with neonatally induced streptozotocin (type 2) diabetes (n-STZ rats). The n-STZ rats were divided into 3 groups (control, ukogi, and dietary fiber). The control group was given the control diet, the ukogi group was given a diet containing 10% ukogi leaves, and the dietary fiber group was given a diet containing 2.5% cellulose and 0.5% pectin. Normal rats were given the control diet (normal). The blood HbA
1c level of the ukogi group was significantly lower than that of the control group. The fecal excretion by the ukogi group was significantly higher than that of the control and dietary fiber groups. The total short-chain fatty acid level in the cecum of the ukogi group was significantly higher than that of the control and dietary fiber groups, the viable cell count of
Bifidobacterium in the ukogi group also being significantly higher than that of the control and dietary fiber groups. These results indicate that ukogi leaves promoted fecal excretion and intestinal fermentation in the n-STZ rats. These actions might have been induced by cellulose, pectin and different components of the dietary fiber in ukogi leaves.
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