巻号一覧
21 巻, 6 号
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入鹿山 且朗, 近藤 孝子, 牛草 貞雄1967 年 21 巻 6 号 p. 371-375
発行日: 1967/02/10
公開日: 2009/02/17
ジャーナル フリーCats fed (CH3Hg)2SO4 developed the same findings as spontaneously affected cats fed the poisonous seafood from Minamata Bay. The organomercury compound in raw organs such as the liver, the kidney, and the bone marrow of the above animals did not transfer to chloroform, but it transferred easily to BAL. The methylmercury compound in organs of cats fed (CH3Hg)2SO4 and rats fed CH3HgI accumulated as the same methylmercury compound. The excretion of mercury in feces of cats fed (CH3Hg)2SO4 was considerably lessoned as compared with that of fed CH3HgCl and (CH3Hg)2S.抄録全体を表示PDF形式でダウンロード (612K) -
石原 房雄1967 年 21 巻 6 号 p. 376-382
発行日: 1967/02/10
公開日: 2009/02/17
ジャーナル フリーWhen rabbits and rats were fed the diet containing excessive salt in proportion to 30gr a day per adult human for two years, cholesterol in blood were increased and P.S.P. was delayed. In the media of the aorta edematous swelling was observed and elastic fibre was greatly swollen and degenerated. In the kidney glomeruli were damaged and endothelial cells of Henle's tubules were degenerated and frayed. These changes were not found in the animals fed a calcium diet with excessive salt together.
The vessels and the kidney of the animals given Saké at the rate of 360cc a day per adult human for two years showed similar changes to those caused by excessive salt, though these were usually less severs. In the liver cells, however, fat degeneration was observed in every instance.抄録全体を表示PDF形式でダウンロード (4012K) -
第2報 肌着の変形について大野 静枝1967 年 21 巻 6 号 p. 383-392
発行日: 1967/02/10
公開日: 2009/02/17
ジャーナル フリーThe deformation of underwears is observed by some experiments. The method of finding out the deformation of underwears, discussed in part 1, proved to be effective enough. The experiments were carried out by four maidens twenty-one and twenty-three years old who tried sixteen underwears made of spun yarn and stretching nylon thread by their same motions of gymnastic exercises. The principal results of the experiments are:
1. The qualitative analysis of the deformation of underwears, shown in Fig. 2 and Fig. 3.
2. The quantitative analysis of the partial deformation of underwears, geometrically shown in Fig. 5.
3. The relations between the contraction of skin and that of unders by motions, shown in Fig. 6.
4. The relations between the representative value of partial deformation of underwears and the increasing rate of surface area of underwears before and after wearing them (R), illustrated in Fig. 9.抄録全体を表示PDF形式でダウンロード (9446K) -
吉柳 節夫, 倉恒 匡徳1967 年 21 巻 6 号 p. 393-396
発行日: 1967/02/10
公開日: 2009/02/17
ジャーナル フリーOne of the interesting characteristics of soots from the point of view of environmental carcinogenesis is strong adsorption of carcinogenic polycylic aromatic hydrocarbons by soots. It has been reported that soots of smaller particle size have stronger adsorptive property and this is a possible explanation for the low carcinogenic potency pertaining to those smaller soots.
The present study was undertaken in order to surface-chemically examine the adsorption of benzo [a] pyrene by carbon black because such study has scarcely been reported. A commercial brand of thermal black and two brands of furnace black were examined. A known amount of a carbon black was thoroughly shaken with a measured volume of various concentrations of cyclohexane solution of benzo [a] pyrene in a tube at 25° or 40°. The resultant equilibrium concentration was estimated spectrophotometrically obtaining adsorption isotherms of the carbon black and cyclohexane system.
The results obtained were as follows:
1) Adsorption isotherms fitted the Freundlich equation except at very low concentrations.
2) Differential heat of adsorption calculated from the isotherms was 5-6kcal/mol.
3) Neither hysteresis loop nor irreversible adsorption was recognized.
It was concluded therefore that adsorption of benzo [a] pyrene by corbon black was essentially physical and not so strong as chemisorption.抄録全体を表示PDF形式でダウンロード (356K) -
脳波(alpha波)との関連について高桑 栄松, 土門 洋哉, 斎藤 和雄, 池田 弘, 大中 吉人, 助川 秀弥1967 年 21 巻 6 号 p. 397-402
発行日: 1967/02/10
公開日: 2009/02/17
ジャーナル フリーThe studies by Adrian, McGregor, Motokizawa and others suggested that the concentration of attention is involved in the blocking of the alpha wave, which is known as the main wave of the human brain waves. Our experiment has been carried out to determine the relationship between alpha-blocking and TAF.
The examinees were seated in a dark room and their brain waves were recorded in three states: eyes closed for 5 minutes, eyes opened for 10 minutes, simple viewing for 10 minutes of the same green light as that used in the TAF-test and testing of TAF for 15 minutes. The relation between alpha-blocking and the concentration of attention especially TAF was observed and discussed.
1. The appearance of the alpha wave decreased in the following order: eye-opening in darkness, simple viewing of green light and TAF-test. (Fig. 3)
2. The appearance of the alapha wave significantly varied with the elapse of time in the state of eye-opening in darkness, but it did not vary in simple viewing of green light nor in the TAF-test. (Fig. 2)
3. The TAF-L did not show any significant change with the elapse of time in the group A (excellent in TAF) and C (inferior in TAF), while in the group B (fair in TAF) the TAF-L of the first three-minute period was significantly better than the values of the later three-minute periods. (Fig. 7)
4. It was observed that the lower in TAF-L, the stronger in alpha-blocking. (Fig. 9)
These results indicate that there is a significant relation between the concentration maintenance and the grade of alpha-blocking, and suggest that the TAF reflects the status of the cerebral cortex in concentrating attention and shows the characteristic pattern of the ability of concentration maintenance.抄録全体を表示PDF形式でダウンロード (2072K) -
第16篇 新算出式-その1 一般用藤本 薫喜, 渡辺 孟1967 年 21 巻 6 号 p. 403-406
発行日: 1967/02/10
公開日: 2009/02/17
ジャーナル フリーSurface area of 201 Japanese from 0 to 70 years of age in both sexes was measured by Gampipaper method. Calculating the regression between the figure or logarithm of surface area and other body measurements (i.e. weight, height etc), it has been found significant difference on their regression between below and over 12 years of age.
Then we have fixed the new calculation formula of surface area of Japanese over 12 years of age as follows:
S=W0.423×0.4230.615×102.65
(S: Surface area in cm2, W: Weight in Kg, H: Height in cm)
This formula have the least error both in mean and variance than Takahira's formula (S=W0.425×H0.725×72.46), which is most widely used in our country, and other formulas.抄録全体を表示PDF形式でダウンロード (363K) -
ピリジン-ホルマリン法によるトリクロルエチレン,クロロホルムおよびベンヂルクロリドの定量由比 顕之介1967 年 21 巻 6 号 p. 407-409
発行日: 1967/02/10
公開日: 2009/02/17
ジャーナル フリーThe author found that formalin stabilized the color developed by the reaction of alkalish pyridine and halogen compound (Fuziwara reaction) and established the simple determination method for trichloroethylene and chloroform in the industrial environment and also benzylchloride was determined.
The sample air was scrubbed through 5ml of pyridine-formalin (9:1) solution and the solution were mixed with 1ml of k-NaOH solution and the amounts of halogen compounds were determined spectrophotometrically.
The method was specific and sensitive (1.5γ of trichloroethylene 2.5γ of chloroform and 1.0γ of benzylchloride scrubbed through 5ml of sampling solution) and should be useful for the determination of these substances in the industrial environment.抄録全体を表示PDF形式でダウンロード (303K) -
百溪 浩, 外山 敏夫, 楠本 昌子1967 年 21 巻 6 号 p. 410-416
発行日: 1967/02/10
公開日: 2009/02/17
ジャーナル フリーThe nonhygroscopic aerosol deposition in the human respiratory tracts according to its particle size was examined by reinhalation method.
The method of the experiment and the results are as follows:
Triphenyl phosphate aerosols (diameter ranges: 0.24μ-3.2μ, S.D.: 0.6μ) was generated to stock into a large Tisseau spirometer by Lauterbach generator. The breathing was performed by 2 healthy human subjects (one male and one female). The inhaled air from the stock spirometer was exhaled to collect into the first Benedict-Roth type spirometer. The air was reinhaled and the exhaled air was collected into the second spirometer. In the same way the last exhaled air was collected into the third spirometer. The rates of respiration used were 10, 15 and 60 per minute and 7 series of the experiment were made. The aerosols were sampled from each spirometer by thermal precipitator, and their frequency distribution, number median diameter (N.M.D.) and standard deviation were determined photomicroscopically.
The total respiratory deposition was estimated to ca 90%, by calculation of the T.P.P. aerosol counts of the samples from the 4 spirometers. No significant change in the deposition rate was found in the different respiration rate. As has been reported by many investigators, the larger the particle diameter, the more the percent of deposition. The N.M.D. of the aerosols in the lastly expired air decreased 0.16μ-0.56μ and its S.D. 0.2μ from the preexperimental values. The total respiratory tract deposition versus particle diameters showed considerable variations among individuals. However, in the vicinity of diameter 0.48μ, a fairly uniform deposition rate, ca. 75%, was found in all cases. This fraction of diameter coincides with Landahl's theoretical minimum deposition size 0.4μ.抄録全体を表示PDF形式でダウンロード (496K) -
百溪 浩1967 年 21 巻 6 号 p. 417-423
発行日: 1967/02/10
公開日: 2009/02/17
ジャーナル フリーThe respiratory tract deposition of nonhygroscopic polystyrene monodisperse aerosols is examined in human subjects. Three kinds of polystyrene particles, diameters of 0.188μ, 0.557μ, and 1.305μ (S.D.: 0.0076μ, 0.0108μ, 0.0158μ respectively) produced by Dow Chemical Co. are used to make monodisperse aerosols for inhalation. The aerosols are generated from the particles suspended in water by a nebulizer (Vaponefrin) under a pressure of 20p.s.i. and are stocked in a 9 litter Benedict-Roth type spirometer to dry and to be inhaled. Subjects are 7 healthy males and 1 healthy female (22∼29 years of age) and they are asked to breathe the aerosols in sitting posture by the nose at respiratory rates of 10, 15 and 20 per minute through a rubber mask connected to the spirometer which depicted tidal volume and respiratory flow rate simultaneously. One experiment durates 1∼2 minutes and 60 series of the experiments are performed in all. The aerosol concentration is measured by Kimoto light scatter photometer (Sinclair-Phoenix type) placed between the spirometer and the mask. The aerosol concentration depicted on the recorder of photometer during one respiration consists of 2 parts, an ascending inspiratory part and a descending expiratory part. From each part average concentrations are estimated and deposition rate are calculated for one cycle respiration. Though there are ca. 15 respiration cycle in one experiment, first 3 of them being excluded to avoid the influence of residual volume, 10 cycles are taken to get an average deposition rate for one experiment. The deposition rate is examined in relation to respiratory rate, tidal volume and respiratory flow rate.
Aerosol depositions in the respiratory tract vary subject to subject, however, the larger the particle size, the higher the percent of deposition. The aerosols of diameters 0.188μ and 0.557μ showed considerably same and low deposition rates in all the respiratory rates used, which suggests the minimum deposition size will exist in the vicinity of these sizes.
The respiratory rate is the next largest variable affecting deposition, that is, the less the respiratory rate the more the deposition, which is most eminently seen in 1.305μ particles. The tidal volume and the flow rate have no relation to the deposition rate.抄録全体を表示PDF形式でダウンロード (3075K) -
香川 順1967 年 21 巻 6 号 p. 424-436
発行日: 1967/02/10
公開日: 2009/02/17
ジャーナル フリーThe validity and the applicability of a sine wave oscillation method for measuring total respiratory flow resistance (viscous resistance of chest lung system) are discussed with a series of experiments by using bodyplethysmograph in man and guinea pig.
The principle of this method, which was introduced by DuBois and developed by Mead, is that the total respiratory flow resistance can be estimated by the bodyplethysmograph through which the sine wave pressure is imposed to the chest lung system to attain a resonant state (to get zero value of the reactance in the simulated electrical R-L-C circuit) by adjusting the frequency of the wave.
The results obtained by using the bodyplethysmographs and the pressure imposing device which are designed by the author are as follows.
1. The frequency of the sine wave oscillation with which the reactance of the chest lung system becomes zero, was found to be 7∼9c.p.s. in both man and guinea pig. And over 12c.p.s. the impedance of the system showed a steep rise.
2. By analysing the flow and its imposed pressure curves, it was found that the total respiratory flow resistance showed continuous change according to a various stage of the flow curve.
3. Used an artificial mouth piece resistor with known resistance of three kinds in man, the frequencies 7∼9c.p.s. also showed the most pertinent reproducibility, and the impedance was overestimated by the below or above frequencies of this range.
4. In applying to the short term inhalation study of low concentration of sulfur dioxide (1.5∼2.0ppm) in man, this technique revealed rapid response and individual difference of the sensitivity of the total respiratory flow resistance after few seconds of the exposure.
5. In long term exposure of guinea pigs to 0.1ppm of toluene diisocyanate vapor without any surgical treatment, the animals showed a repeated day to day response with different individual sensitivity, and when sodium chloride aerosols were added the response of the total respiratory flow resistance was affected in meaningful pattern.
From the results above, it can be said that this procedure is a relevant and sensitive method to evaluate a behavior of the respiratory air way in both man and guinea pig particulary in short or long term study of various environmental toxic materials.抄録全体を表示PDF形式でダウンロード (10863K)
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