巻号一覧
62 巻 (2007)
- 4 号 p. 939-
- 3 号 p. 881-
- 1 号 p. 3-
62 巻, 4 号
選択された号の論文の3件中1～3を表示しています
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総説
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関 明彦, 瀧川 智子, 岸 玲子, 坂部 貢, 鳥居 新平, 田中 正敏, 吉村 健清, 森本 兼曩, 加藤 貴彦, 吉良 尚平, 相澤 ...2007 年 62 巻 4 号 p. 939-948
発行日: 2007/09/15
公開日: 2008/05/16
ジャーナル フリー‘Sick house syndrome’ (SHS) is a health issue that closely resembles sick building syndrome (SBS) that had occurred in European countries. The aim of this review is to clarify the characteristics of SHS by reviewing previous reports rigorously. We propose the definition of SHS as “health impairments caused by indoor air pollution, regardless of the place, causative substance, or pathogenesis”. Cases of SBS are reported to occur predominantly in offices and sometimes schools, whereas those of SHS are usually found in general dwellings. In many cases, SHS is caused by biologically and/or chemically polluted indoor air. Physical factors might affect the impairments of SHS in some cases. It is considered that symptoms of SHS develop through toxic, allergic and/or some unknown mechanisms. Psychological mechanisms might also affect the development of SHS. It is still unclear whether SBS and SHS are very close or identical clinical entities, mostly because a general agreement on a diagnostic standard for SHS has not been established. Previous research gradually clarified the etiology of SHS. Further advances in research, diagnosis, and treatment of SHS are warranted with the following measures. Firstly, a clinical diagnostic standard including both subjective and objective findings must be established. Secondly, a standard procedure for assessing indoor air contamination should be established. Lastly, as previous research indicated multiple causative factors for SHS, an interdisciplinary approach is needed to obtain the grand picture of the syndrome.抄録全体を表示PDF形式でダウンロード (1736K) -
村田 勝敬, 嶽石 美和子, 島田 美幸, 佐藤 洋2007 年 62 巻 4 号 p. 949-959
発行日: 2007/09/15
公開日: 2008/05/16
ジャーナル フリーIn epidemiological studies on the health effect of methylmercury (MeHg) exposure, maternal-hair mercury concentration has been used as an exposure biomarker because of its ease of collection and capability to recapture the exposure history. However, artificial hair-waving reduces the mercury concentration and there is little agreement about which part of the hair strand properly represents fetal exposure. We presented an overview of the studies addressing umbilical cord and mercury in PubMed and evaluated the usefulness of umbilical cord mercury concentrations as biomarkers of fetal exposure to MeHg. The mean total mercury (T-Hg) concentration in cord blood was between 0.5 and 35.6μg/l, and the cord blood-to-maternal blood ratio of T-Hg concentrations was estimated to be approximately 1.5. MeHg concentrations in dried cord tissue did not exceed 0.4 μg/g in Japanese populations without particular exposure to MeHg. Dried cord tissue appeared to be better than wet tissue because the definition of wet weight of the umbilical cord is ambiguous. Both cord-blood and cord-tissue mercury concentrations seemed to correlate closely with maternal-hair and maternal-blood ones. Since cord mercury concentrations are a direct exposure biomarker of the fetus and the cord blood-to-maternal blood ratio of mercury differed markedly among mother-child pairs, mercury concentration in cord blood or dried cord tissue should therefore be used in assessing the possible effects of fetal exposure to MeHg on the susceptible brain. Further studies are required to clarify at which period of exposure during gestation the cord mercury concentration represents in relation to mercury concentrations in maternal segmental hair.抄録全体を表示PDF形式でダウンロード (1296K)
原著
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杉村 久理, 堀口 逸子, 清水 隆司, 丸井 英二2007 年 62 巻 4 号 p. 960-966
発行日: 2007/09/15
公開日: 2008/05/16
ジャーナル フリーObjectives: We studied 1365 male workers at a Japanese computer worksite in 2004 to determine the relationship between employees' time management factor of visual display terminal (VDT) work and General Health Questionnaire (GHQ) score.
Methods: We developed questionnaires concerning age, management factor of VDT work time (total daily VDT work time, duration of continuous work), other work-related conditions (commuting time, job rank, type of job, hours of monthly overtime), lifestyle (smoking, alcohol consumption, exercise, having breakfast, sleeping hours), and the Japanese version of 28-item General Health Questionnaire (GHQ). Multivariate logistic regression analyses were performed to estimate the odds ratios (ORs) of the high-GHQ groups (>6.0) associated with age and the time management factor of VDT work.
Results: Multivariate logistic regression analyses indicated lower ORs for certain groups: workers older than 50 years old had significantly a lower OR than those younger than 30 years old; workers sleeping less than 6 h showed a lower OR than those sleeping more than 6 h. In contrast, significantly higher ORs were shown for workers with continuous work durations of more than 3 h compared with those with less than 1 h, those with more than 25 h/mo overtime compared with those with less, those doing VDT work of more than 7.5 h/day compared with those doing less than 4.5 h/day, and those with more than 25 h/mo of overtime compared with those with less.
Conclusion: Male Japanese computer workers' GHQ scores are significantly associated with time management factors of VDT work.抄録全体を表示PDF形式でダウンロード (769K)
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