巻号一覧
59 巻 (2004)
- 4 号 p. 383-
- 3 号 p. 301-
- 1 号 p. 5-
59 巻, 4 号
選択された号の論文の4件中1～4を表示しています
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戸田 雅裕, 門田 和之, 久保 和毅, 森本 兼曩2004 年 59 巻 4 号 p. 383-386
発行日: 2004/11/15
公開日: 2009/02/17
ジャーナル フリーObjective: To assess the reliability and validity of a cellular phone dependence questionnaire (CPDQ) we designed.
Methods: The CPDQ, a 20-item self-rated scale, was given to 168 healthy female university students (mean age, 21.7 years). Each question uses a 0 to 3 response scale; a higher score indicates greater dependence. The reliability and validity of the CPDQ were assessed by an internal consistency estimate and a factor analysis, respectively. Question scores were then summed to provide a cellular phone dependence score ranging from 0 to 60.
Results: The reliability coefficient (Cronbach's alpha) for the CPDQ was 0.86. In addition, six significant factors were extracted by factor analysis for the 20 items of the CPDQ. The cellular phone dependence score showed a normal distribution (Kolmogorov-Smirnov's test), and the average (±SD) was 33.2±8.7.
Conclusion: These findings suggest that the CPDQ is a useful scale for rating cellular phone dependence.抄録全体を表示PDF形式でダウンロード (639K) -
乳歯切歯エナメル質を用いた評価瓜生 務, 北條 祥子, 貴田 晶子, 西川 雅高, 吉永 淳2004 年 59 巻 4 号 p. 387-394
発行日: 2004/11/15
公開日: 2009/02/17
ジャーナル フリーObjective: The purpose of this study was to examine the relationship between fetal lead exposure and birth weight, using deciduous incisor enamel as a biomarker and laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) for analysis of lead.
Methods: We asked dental clinics (n=11) and kindergartens (n=11), mainly in the Tokyo metropolitan area and Miyagi Prefecture, and parents to enroll donors of exfoliate deciduous incisors. Donors who consented to this study voluntarily sent deciduous incisors and questionnaires to the authors between March and October, 2003. The Pb/Ca ratios of inner enamel samples were determined by LA-ICP-MS. The relationship between the lead-to-calcium ratio in the enamel and the birth weight was evaluated by stepwise multiple linear regression analysis.
Results: One hundred forty-one subjects (male, 72; female, 69) were enrolled in this study. The mean Pb/Ca ratio in the enamel was as low as 0.24mg-Pb/kg-Ca (SD=0.17). Stepwise multiple linear regression analysis extracted the following maternal variables with a positive coefficient with birth weight: gestational age (p<0.01), weight gain during pregnancy (p<0.01), prepregnancy BMI (body mass index, p<0.01), and parity (p<0.05). Lead concentration in the enamel was significantly negatively associated with birth weight (p<0.05).
Conclusions: Our study indicated that lead concentration in the enamel was inversely related to birth weight. This association was found in a population of which the mean blood lead level was estimated to be as low as about 1μg/dl. We concluded that in utero low lead exposure decreased birth weight, within the normal range of birth weight.抄録全体を表示PDF形式でダウンロード (1311K) -
井上 節子, 長岡 功, 石原 恵, 笠岡 誠一, 中島 滋, 岩井 秀明2004 年 59 巻 4 号 p. 395-402
発行日: 2004/11/15
公開日: 2009/02/17
ジャーナル フリーObjectives: First, we observed that copper and histidine levels were increased in the sera of undernourished women. The objective of this study was to clarify the reason for the increase in copper and histidine. Furthermore, we tried to determine the compound (s) to which the increased copper was binding, and examined the effect of the increased copper and histidine on lipid peroxidation. Methods: We investigated young women's diets and took blood samples, and the contents of histidine in the sera were determined by HPLC. The contents of copper were determined by flameless atomic absorption spectroscopy. The subjects were classified into three groups according to the concentration of histidine in the sera. The contents of copper and lipid peroxide in the sera were compared among the high histidine group and the other groups. We also examined the ability of the complexes to prevent LDL oxidation induced by copper, using an in vitro assay. Results: The contents of lipid peroxide were lower in the high histidine group than in the other groups. Furthermore, the complexes of histidine and copper inhibited the formation of peroxidized lipids in an in vitro assay. Conclusions: These results indicate that histidine masks copper, reducing oxidation reaction. They also suggest that the complexes are suited for plasma antioxidation, preventing oxidative modification of lipids in the sera of undernourished women. The increased histidine appeared to be an effective trap for active oxygen.抄録全体を表示PDF形式でダウンロード (1362K) -
藤巻 可弓, 荒川 千夏子, 吉永 淳, 渡辺 知保, 芹澤 滋子, 今井 秀樹, 白石 寛明, 水本 賀文2004 年 59 巻 4 号 p. 403-408
発行日: 2004/11/15
公開日: 2009/02/17
ジャーナル フリーObjective: The daily bisphenol A (BPA) intake level of Japanese pregnant women was surveyed based on the measurement of the urinary excretion level of a BPA metabolite.
Methods: Spot urine samples were collected from 56 pregnant women who visited the gynecology division of a hospital for a routine health check between June and October 2003. The urinary concentrations of the BPA metabolite and creatinine were measured by GC/MS/MS and spectrophotometry, respectively. Daily BPA intake was assumed to be equal to daily excretion.
Results: The daily intake of BPA among Japanese pregnant women was estimated to be in the range of <0.3 to 7.9μg/day (median<2.0μg/day), being consistent with the levels in previous studies for non-pregnant Japanese women. This level was far below the current Acceptable Daily Intake (0.01mg/kg/day) which was set by the European Commission. The maximum estimated intake per body weight (0.16μg/kg/day) reached 1/10 of the Lowest Adverse Effect Level of BPA for pregnant mice for a reproductive effect on the offspring (2μg/kg/day).
Conclusion: It is desirable to lessen BPA intake from a precautionary viewpoint, particularly in pregnant women.抄録全体を表示PDF形式でダウンロード (793K)
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