In recent years some of the aromatic amines such as 5-nitroacenaphthene and 5-aminoacenaphthene have been in use in industry as intermediates of fluorescent whitening agents.
Experiments were made on mice, by the author, to investigate possibilities of carcinogenicity and the results are as follows: these chemicals injected intraperitoneally into mice for 18 months induced malignant tumours such as leukemia, recticulum cell sarcoma, etc. in about 40% of the mice and wax pellets containing 5-aminoacenaphthene, when implanted in the bladders of mice revealed a mild carcinogenic effect on the ephithelium.
These results suggest that the use of these new aromatic amines in modern industry should be revaluated in order to prevent occupational bladder cancer that may occur among industrial workers.

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Recently, concept and methodology of multiphasic mass screening examinations have developed and the need for application in school health practice has increased a great deal. Such being the case, the author felt the necessity to analyze the correlation between complaints expressed by subjective insight and the personalities investigated by psychological methods.
Okayama Medical Index (O.M.I.) has been adopted as a health questionnaire, and those having many complaints, or those having little or no complaints according to this questionnaire were investigated by Minnesota Multiphasic Personality Inventory (MMPI) and Yatabe-Guilford Personality Inventory (Y-G).
The results were as follows:
1. The students of senior high school were verified to be mentally healthy and suitiable as subjects for study purposes. The students of junior high school were not as suitable as examinees for MMPI testing.
2. Those having little or no complaints by O.M.I. include persons of high score in Pa and Sc. Those having many complaints include persons of high score in neurotic scales such as Hs, Hy and Pt. Though persons of many complaints can be judged as neurotic, there is much doubt as to whether or not healthy persons with little or no complaints can be accurately evaluated.
3. Those having little or no complaints by O. M. I. include many persons possessing high levels of social adaptability as well as emotional stability. On the contrary, those having many complaints included persons with low levels of social adaptability and emtional instability. However, it cannot be concluded that persons having little or no complaints are always mentally healthy. Further observation and investigation is required.
4. The investigations of the author reveal that complaints as expressed by subjective insight correlate with personality characteristics.

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Recently there is a social need for mental health administration and this is receiving attention in Public Health Practice. Several methods using personality inventories or health questionniares have been used to meet such a need.
For the evaluation of these methods, the author used MMPI, translated and modified by Tokyo University and Sociometric testing. These were applied for use on 1206 male and 334 female students 15 or 16 years of age in 3 vocational high schools.
The results were as follows;
1. By group survey, questioning orally, MMPI was found to be valid as a mass examination.
2. Validity Scale (Fr) had high correlations to clinical scales, while Scale (F) did not reveal the correlation as Scale (Fr).
3. AS far as the correlation among scales, Scale (L), (6) and (8) were found to be independent. Scale (1), (2), (3), (4), (7), (10) showed high correlations. Scale (9) had different correlations in each group.
4. It was recognized that the mean profile of MMPI in each group had particular relation to the characteristics of that group.

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To precisely affirm the result of Report I, the author has analyzed the relationship between the MMPI and the Sociometric test used for examination of school groups. The selection of subjects was the same as that used for Report I.
The results were as follows:
1. In each class the mean profile of MMPI and the psychological structure for Sociometric testing revealed a close relationship between the two.
2. The relationship between the individual personality analyzed by MMPI and one's sociometric status was found to change dynamically according to the difference in characteristics of schools or classes.
3. It was observed that the mean profiles of MMPI of leaders, favorites, disliked and persons of high or low sociometric status revealed significant and different patterns according to their school characteristics.

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It has been previously reported that inorganic phosphate content decreased in the diencephalon and upper part of the mesencephalon of rabbit brain under conditions of noise. For this reason the present investigation was undertaken to observe the changes in the Mg-ATPase activities of rabbit brains and the ATP concentrations of rat brains under different physical conditions. The physical conditions used were similar to those of previous reports.
The Mg-ATPase activity was determined by MARION-GORE'S method, and the ATP concentration was measured by BOERINGER'S reagent.
The following results were obtained:
1. In the control group. Mg-ATPase activities of the telencephalon, upper part of the mesencephalon, and cerebellum were higher than that of the lower part of mesencephalon, pons and medulla oblongata.
2. Under conditions of noise, Mg-ATPase activities of the telencephalon and the upper part of the mesencephalon decreased significantly, but this was not observed under conditions of cold or immobilization.
3. The average value for ATP concentrations of rat brains in the control group was 0.849 mol/g (SE: ±0.081).
4. ATP concentrations of rat brains increased significantly under conditions of noise but were not changed under conditions of cold or immobilization.

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An ortho-nitrophenol solution was injected into the intestine which had been removed from an anesthetized mouse by placing a ligature at the duodenum and at the rectum. The intestine was then incubated in Ringer's solution at 37°C and the ortho-nitrophenol was found to be reduced to ortho-aminophenol.
At the same time, it was found that ortho-nitrophenol which was incubated with the intestinal flora in bouillon was reduced to ortho-aminophenol.
The results of our experiment seem to suggest that reduction is induced in almost no time by the intestinal flora when ortho-nitrophenol is introduced into the intestine and that some aromatic nitro compounds introduced into the system may be reduced to amino compounds in the intestine before they are carried to the liver to be reduced.

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The skin temperature, heart rate and finger-tip plethysmogram were measured in 5 medical students during and after smoking one cigarette, inhaled at three different depths, viz. deep inhalation, ordinary inhalation, and puffing.
Significant changes were observed during smoking in the decrease of finger skin temperature, the increase of heart rate, the shortening of crest time and propagation time, the reduction of volume change and the increase of dicrotic index compared with those during sham smoking. The shortening of crest time and propagation time, the increase of heart rate and the reduction of finger skin temperature were more marked in the subjects whose inhalation was deeper and the return of these parameters after smoking to their initial level were delayed according to the depth of the inhalation.
Therefore the vascular responses in cigarette smoking may be dependent on the depth of the smoker's inhalation.

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