The changes of hemodynamics during bathing in patients with heart diseases were studied by invasive methods using a Swan-Ganz catheter and UCG. As a population, we have used 37 peatients with heart disease, ages 20 to 76 (average age 52.9). There were 26 cases of myocardial infarction, 5 cases of valvular disease, 5 cases of cardiomyo pathy, and 1 case of VSD. Bathing was done with tap water in a Hubbard tank, for 10 minutes at 40°C and for 5 minutes at 43°C in a supine position. Arterial pressure, heart rate, pulmonary arterial pressure, pulmonary wedge pressure, right atrial pressure, cardiac output, stroke volume and stroke work index were increased during bathing and decreased after bathing. Systemic vascular resistance and pulmonary arteriolar resistance were decreased during bathing. Their changes were marked with a bath of 40 to 43°C. These findings suggest that preload may be increased during bathing, and preload and afterload reduced after bathing. Hydrostatic pressure, autonomic nervous reflexes or endocrine system were thought of as possible reasons for the increase in pulmonary arterial pressure. Because pulmonary arterial pressure, pulmonary wedge pressure and right atrial pressure increased during bathing even though systemic vascular resistance and pulmonary arteriolar resistance decreased, increase in venous return was thought of as the biggest possibility. And because the patients with low cardiac function could not control the extent of increase in venous return, pulmonary arterial pressure increased markedly in patients with low cardiac function. The patients with myocardial infarction were classifed into a group showing elevation of pulmonary arterial pressure (PAP) and a group showing no elevation of PAP. The group showing elevation of PAP, compared with that without PAP elevation, included many cases of severe myocardial infarction deter-mined by Forrester's classification, Killip's classification and Peel's prognostic index at admission to hospital. Among these patients showing PAP elevation, there were more cases having low physical work capacity and low ejection fraction at discharge from hospital than among the patients without PAP elevation.

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Actual changes in tissue partial pressures of each gas and tissue perfusion with serial artificial CO₂ bathing were evaluated by means of medical mass spectrometry using 5 rabbits.
An artificial CO₂ bath was prepared by adding “BUB”-KAO, a 50g sodium hydrogencarbonate and succinic acid tablet producing fine CO₂ bubbles in water of constant temperature 20-litre tub at 36-37°C.
Regional tissue perfusion volume was determined on the basis of a clearance curve for Argon tissue partial pressure which was monitored by an on-line computer system with mass spectrometry.
Increase in subcutaneous tissue PCO₂ changed from 27% to 10%, and in PO₂ from 12% to 5% on average by serial bathing every day for 4 weeks, on the other hand tissue perfusion volume was increased in 3 out of 5 cases; from 20.85±3.56 (X±SE) ml/100g/min, SD=6.71, p<0.05 to 25.23±8.00 (X±SE) ml/100g/min, SD=6.96, p<0.05.
CO₂ has been shown to be locally absorbed through the skin resulting in the elevation of subcutaneous tissue CO₂ partial pessure which decreases depending on the tissue perfusion irrespective of metabolic processes. It is, therefore, assumed that the elimination of absorbed constituents by serial bathings is not caused by a decrease in the percutaneous absorption rate but an increase in washing out rate by the improved tissue perfusion.

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Artificial CO₂-bath was prepared with a tablet (50g): made from sodium bicarbonate and succinic acid, putting simply in plain water bath tub of 100-200 litre at 40C.
The effect of artificial CO₂-bath was studied in relation to the change in blood lactic acid which is thought to be indicative of the physical fatigue.
It has been clearly demonstrated experimentally using rats that the blood lactic acid after exercise is significantly reduced as compared both to a plain and an artificial Na₂ SO₄-NaHCO₃ bathing.
A favorable effect of the artificial CO₂-bath was also confirmed clinically by a relief from the stiff pain following maximal abdominal muscle exercise.

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Using the peripheral nerves of human subjects, a study was conducted on the activity of efferent sympathetic postganglionic fibers controlling the soleus, and on the basis of tonus, its response to acupuncture stimulation was observed.
1. Microneurography is efficient as a method for monitoring the participation of the sympathetic nervous system in response to acupunture stimulation.
2. The spontaneous dischrge of the vasoconstrictor nerve controlling the soleus shows a cycle in which the activity varies with changes in the arterial blood pressure. This experiment revealed that this cycle was affected by acupuncture stimulation. The changes in degree of this affect were dependent upon the specificity of an individual.
3. The method, ‘Koshi’, one the classical approaches in the theory of acupuncture, can be used as a method of changing the regional circulatory movement of a leg other than the one to which acupuncture stimulation is applied.

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Heinrich Neu Fahrland Sanatorium in Potsdam, Bad Elster, Bad Branbach, and Bad Liebenstein were visited in June, 1985. Spa treatment in D. D. R. is organized as a part of total health care programm under direct control of the Ministry of Health. Cardio vascular diseases are the top cause of mortality in D. D. R. and therefore spa treatment or rather “cure” therapy is widely used for prevention, therapy and rehubilitation of these direases. 28 health resorts, 31 sanatoria and 4 Kneipp bathresorts were listed in Bäderbuch der D. D. R. edited by Prof. H. Jordan.

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