Five active components were isolated from three kinds of plant-extracts which inhibited the growth of silkworm larvae,
Bombyx mori L. Growth inhibitory effects of the compounds were investigated on the larvae. 1. An active component isolated from
Spilanthes acmella var.
oleracea CLARKE was identified as spilanthol. When the 4th instar larvae were fed on an artificial diet containing spilanthol at a concentration of 200ppm, they showed 100% mortality in 6 days. 2. Digitalin and digitoxin were presumed to be the active principles in
Digitalis purpurea LINN. Digitalin produced an atomic effect on the larval body at a dose of 100ppm, whereas digitoxin showed the same effect at a concentration of 25ppm, and 100% mortality at 100ppm in 6 days. 3. From
Magnolia kobus DC. were isolated two active components, which were identified as sesamine and kobusin, a lignan hitherto unknown. Kobusin produced a growth-inhibitory effect on the 2nd instar larvae at a concentration of 400ppm, followed by 100% mortality in 5 days. The activity of sesamine was about half of that of kobushin. 4. Two active components were isolated from
Justica procumbens LINN. and identified as justicidin A and B, which gave 100% and 90% mortality, respectively, on the 4th instar larvae at a dose of 20ppm in 6 days.
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