The prodromal symptoms of schizophrenia remain difficult to characterize. Interest is, therefore, being focused on the identification of early warning signs of a recurrent clinical episode in order to provide optimal care for such patients. However, as with the characterization of prodromal symptoms, identifying a stage scale for these early warning signs is difficult and another quantitative and continuous measuring method seems to be required. In an attempt to identify such a warning sign, we counted the number of paces of patients prior to a clinical episode, because we speculated that this factor correlated with changes in the severity of mental symptoms. We attached a pedometer to eight long-term hospitalized schizophrenic patients. The number of paces was measured daily from Monday to Friday for a period of about one year, with the average number of paces obtained from the total number of steps every week. Simultaneously, the severity of mental symptoms was measured weekly. Five of the eight patients showed a significant correlation between number of paces and increasing severity of schizophrenic symptoms. In addition, number of paces changed significantly from 4 weeks to 1 week before the manifestation of mental symptoms. Therefore, measuring the number of paces may effectively determine the probable onset of a deterioration in the mental state of certain schizophrenic patients and enable nursing staff to early intervention.
View full abstract