The Review of Laser Engineering
Online ISSN : 1349-6603
Print ISSN : 0387-0200
ISSN-L : 0387-0200
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Volume 28, Issue 5
Displaying 1-11 of 11 articles from this issue
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  • On the Role of LDs in the 21st Century
    Hirobumi TAKANASHI
    2000 Volume 28 Issue 5 Pages 269
    Published: May 15, 2000
    Released on J-STAGE: March 17, 2010
    DOIhttps://doi.org/10.2184/lsj.28.269
    JOURNAL FREE ACCESS
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  • Possible Contribution of Laser Technology to Medical Diagnosis and Treatment
    Hideo TASHIRO
    2000 Volume 28 Issue 5 Pages 270
    Published: May 15, 2000
    Released on J-STAGE: March 17, 2010
    DOIhttps://doi.org/10.2184/lsj.28.270
    JOURNAL FREE ACCESS
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  • Laser Spectral Analysis of Biomedical Materials-Functional Diagnosis by Laser Spectroscopy and New Spectral Analysis Methods
    Yukihiro OZAKI, Xiaoming DOU
    2000 Volume 28 Issue 5 Pages 271-280
    Published: May 15, 2000
    Released on J-STAGE: March 17, 2010
    DOIhttps://doi.org/10.2184/lsj.28.271
    JOURNAL FREE ACCESS
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    Functional medical diagnosis by laser molecular spectroscopy together with new spectral analysis methodshas recently made remarkable progress because of three major reasons. One is rapid development of lasertechnology. A variety of new lasers including new semiconductor lasers and tunable lasers have becomeavailable in laser spectroscopy of biomedical samples. In the field of biomedical spectral analysis, the advancesin near-infrared (NIR) lasers have been very important. The other is the progress in detectors andspectrometers such as CCD and multichannel spectrometers in the NIR region. Yet another is the developmentof spectral analysis methods such as chemometrics, neural network, and two-dimensional correlation spectroscopy.The main purpose of this review paper is to report the progress in the modern spectral analysis methodsand their applications to the field of medical functional diagnosis.
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  • [title in Japanese]
    2000 Volume 28 Issue 5 Pages 280-280,285
    Published: May 15, 2000
    Released on J-STAGE: March 17, 2010
    DOIhttps://doi.org/10.2184/lsj.28.280
    JOURNAL FREE ACCESS
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  • Fluorescence Image Pattern of Pathemaregion Using Photosensitizer
    Katsuo AIZAWA, Tadatoshi KAWASAKI
    2000 Volume 28 Issue 5 Pages 281-285
    Published: May 15, 2000
    Released on J-STAGE: March 17, 2010
    DOIhttps://doi.org/10.2184/lsj.28.281
    JOURNAL FREE ACCESS
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    Epifluorescence stereoscope system and angioscope analyzer system for photodiagnosis with a photosensitizer (mono-L-aspartyl chlorin e6: NPe6) assembled diode laser system. Using epifluorescence stereoscopesystem, fluorescence image pattern of NPe6 that accumulated in the submucosal tumor on esophagus. Atheroscleroticlesions on coronary artery were measured for the photodiagnosis with a Npe6 using an angioscopeanalyzer system.
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  • Recent Advances in Optical Tomography Techniques for Biomedical Imaging
    Kin Pui CHAN, Naohiro TANNO
    2000 Volume 28 Issue 5 Pages 286-290
    Published: May 15, 2000
    Released on J-STAGE: March 17, 2010
    DOIhttps://doi.org/10.2184/lsj.28.286
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    Optical imaging of biological tissues is a fast growing field that brings state-of-the-art laser and optical technologiestogether with physical and clinical sciences. Many new concepts and detection techniques developedin the past several years have evolved this field from basic study of photon migration in turbid media to clinicalpractice. This paper reviews some of the recent developments in the study of optical tomography, which alsomay imply the future direction of biomedical imaging by means of optical methods.
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  • Medical Applications of Infrared Lasers
    Kunio AWAZU
    2000 Volume 28 Issue 5 Pages 291-297
    Published: May 15, 2000
    Released on J-STAGE: March 17, 2010
    DOIhttps://doi.org/10.2184/lsj.28.291
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    Infrared lasers for medical applications were summarized in this review. CO2 laser is the first infrared medicallaser. Use of conventional medical lasers depends on absorption coefficient of water. Nd: YAG laser is used incoagulation surgery. Ho: YAG laser is used to cut or vaporize tissue. Er: YAG laser is used in caries therapybecause of its large absorption coefficient of water. Pulse lasers are used because less than 1 μsec pulse lasersinduce less thermal effect than CW lasers. The medical applications of FELs have merits of wavelengthselectivity and psec-nsec pulse structure. When the wavelength can be tuned to the vibrational mode, theinfrared lasers will be widely used on biomedical field in the near future because the lasers can activate bindingsbetween bio-molecules directly.
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  • Tunable Solid State Laser for Photo-Medical Science
    Satoshi WADA, Hidetoshi SATO
    2000 Volume 28 Issue 5 Pages 298-302
    Published: May 15, 2000
    Released on J-STAGE: March 17, 2010
    DOIhttps://doi.org/10.2184/lsj.28.298
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    This paper presents a brief review of tunable solid state lasers and topics on medical applications. It alsodescribes the electronically tuned Ti: sapphire laser developed in our laboratory with a function of random-andrapid-wavelength tuning. The laser equipped with an acousto-optical tunable filter realizes a wide tunablerange from 700 to 1000 nm. We used the laser as a light source for absorption spectroscopy allowing us tomeasure transmission spectra of a thick human tissue in a totally noninvasive manner.
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  • Progress of Rejection Observed by in vivo Near Infrared Spectroscopy
    Masaru KANASHIRO
    2000 Volume 28 Issue 5 Pages 303-308
    Published: May 15, 2000
    Released on J-STAGE: March 17, 2010
    DOIhttps://doi.org/10.2184/lsj.28.303
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    With the intension of exploiting latent information in a continuous spectrum we constructed an in vivo nearinfrared spectroscopy system including multicomponent analysis. The progress of acute rejection inorthotopically transplanted rat liver was monitored with this system. In the course of this study we found thatnitrosylhemoglobin could be quantitated. The results revealed that increase of water content and decrease ofthe levels of oxyhemoglobin and oxidized form of cytochrome c oxidase, corresponding to edema and circulatoryfailure in revascularized graft, took place at an advaced stage of rejection. On the other hand, rapidincrease of nitrosylhemoglobin occured at the onset of the immune response, when any tissue damage was notbrought about. Treatment with an immunosuppressant depressed these events. We also studied elongation oflight path length due to multiple scattering in red blood cell suspensions and in a gerbil head under hypoxia.
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  • Fiber Delivery of 20 MW Laser Pulses and Its Applications
    Masaki YODA, Yuji SANO, Naruhiko MUKAI, Thomas SCHMIDTUHLIG, Gerd MARO ...
    2000 Volume 28 Issue 5 Pages 309-313
    Published: May 15, 2000
    Released on J-STAGE: March 17, 2010
    DOIhttps://doi.org/10.2184/lsj.28.309
    JOURNAL FREE ACCESS
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    The authors delivered 20 MW laser pulses through an optical fiber with a core diameter of 1.5 mm and a lengthof 5 m, using a beam homogenizer which divided laser beam into 7×7 squares and folded it up into a singlesquare of 0.81×0.81 mm at the front entrance of the fiber. The laser pulses, which were emitted from afrequency-doubled Nd: YAG laser with an energy of 138 mJ and a pulse duration of 5 ns, were irradiated to theall silica step index multi-mode fiber via the homogenizer. The peak intensity of laser pulses reached 42 TW/m2 (4.2 GW/cm2) at the fiber entrance. As an example of practical applications, we demonstrated the feasibilityof fiber-delivered laser peening through experiments in which the residual stress of an SUS304 test samplewas improved from tensile to compressive.
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  • Fundamentals of Laser Chemistry I: Ultrafast Spectroscopy in Photochemistry
    Tsuyoshi ASAHI
    2000 Volume 28 Issue 5 Pages 314-318
    Published: May 15, 2000
    Released on J-STAGE: March 17, 2010
    DOIhttps://doi.org/10.2184/lsj.28.314
    JOURNAL FREE ACCESS
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