Practica Oto-Rhino-Laryngologica
Online ISSN : 1884-4545
Print ISSN : 0032-6313
ISSN-L : 0032-6313
Volume 102, Issue 5
Displaying 1-15 of 15 articles from this issue
Editorial
  • Kenji Suzuki
    2009 Volume 102 Issue 5 Pages 325-332
    Published: 2009
    Released on J-STAGE: March 03, 2011
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    The prevalence of sleep apnea syndrome (SAS) is relatively high, with SAS patients said to comprise 3.3% of males and 0.5% of females in Japan, and nearly 4% of males and nearly 2% of females in the United States. The habitual snoring associated with SAS is said to be a symptom of obstructive sleep apnea syndrome (OSAS).
    The primary sites of obstruction are usually the nasal cavity, pharynx, and larynx, within the scope of otolaryngology. For the treatment of SAS, a knowledge of the sites and types of obstruction and proper choice of the most suitable treatment method from among the surgical (PPDS, UPPP, etc.) and conservative (NCPAP, etc.) treatments available are said to be the most important. As otolaryngologists, we are in a neutral position regarding making such choices, however, as surgeons, we tend to select surgery over conservative treatment.
    For OSAS patients with an advanced age, marked disease complications, and severe obesity, and UPPP surgery failure cases, we should choose conservative instead of surgical treatment. The most important point is that we provide the most suitable treatment method for each OSAS patient.
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Clinical color photographs
Original articles
  • Hiroshi Kajikawa, Takefumi Kamakura, Naoki Matsushiro, Takahiro Kitamu ...
    2009 Volume 102 Issue 5 Pages 337-341
    Published: 2009
    Released on J-STAGE: March 03, 2011
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    Sudden sensorineural hearing loss is commonly knwon as inner ear disease, although little is known about its cause in most cases. We evaluated 383 patients with sudden sensorineural hearing loss using magnetic resonance imaging (MRI). In 8.1% of the patients, MRI examination revealed some abnormal findings that may be associated with sudden sensorineural hearing loss: acoustic tumor was noted in 1%, abnormality of the vertebral-basilar artery in 1%, and infarction around the brainstem in 0.8%. In these cases, using MRI at an early stage of examination, we can establish the correct diagnosis of and treatment for hearing loss.
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  • Keiko Kashiba, Toru Seo, Naoki Saka, Masafumi Sakagami
    2009 Volume 102 Issue 5 Pages 343-346
    Published: 2009
    Released on J-STAGE: March 03, 2011
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    On March 3, 2005, a 28-year-old woman consulted our hospital complaining of truncal ataxia and disequilibrium. She had experienced a common cold at the end of January. Since she could not stand alone due to severe truncal ataxia, she was hospitalized. Electronystagmography including eye tracking test, optokintic nystagmus pattern test and caloric test showed normal results. Flutter-like oscillations of the eyes appeared when she changed her eye position. Finger-to-nose test results were showed normal. There were no apparent intracranial lesions on MR imaging. She was diagnosed as having acute cerebellitis, because cerebellar symptoms had occurred after a common cold. Her symptoms were medicated and subsequently showed improvement on March 31. It was suggested that cerebellitis was limited within the fastigial nucleus and the anterior to middle portion of vermis in this case.
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  • Kosuke Sagawa, Tomonori Terada, Nobuo Saeki, Nobuhiro Uwa, Masafumi Sa ...
    2009 Volume 102 Issue 5 Pages 347-351
    Published: 2009
    Released on J-STAGE: March 03, 2011
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    Most cancers of the tongue arise on the lateral borders and that on the dorsum is rare. Several reports indicate that cancer of the dorsum of the tongue comprises 0% to 7.2% of all tongue cancer.
    We report a case of squamous cell carcinoma arising from the dorsum of the tongue in a 65-years-old woman. Intraoral examination demonstrated a tumor measuring 42×40×5 mm in the midline of the dorsum of the tongue. The diagnosis was squamous cell carcinoma. Total resection of tumor and bilateral neck dissection were performed under general anesthesia. During follow up for about 1.8 years, there has been no sign of recurrence or metastasis.
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  • Keisuke Yamamoto, Ryuichi Mochizuki, Masahiro Kawamoto, Kazumasa Oka, ...
    2009 Volume 102 Issue 5 Pages 353-358
    Published: 2009
    Released on J-STAGE: March 03, 2011
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    We report a case of MALT (mucosa-associated lymphoid tissue) lymphoma in the parotid gland. MALT lymphoma, an extranodal low-grade lymphoma arising in the stomach, salivary gland or thyroid gland is caused by chronic inflammation such as chronic gastritis, Hashimoto’s disease and Sjogren syndrome.
    An optimal therapy has not been established for MALT lymphoma of the salivary gland.
    The patient was a 68-year-old woman with swelling of the left parotid gland.
    A left parotid tumor was diagnosed by CT and MRI, and was treated surgically. The postoperative pathological diagnosis of the left parotid tumor was MALT lymphoma: there were centrocyte-like cells, plasma cells with ditcher bodies, and a lymphoepithelial lesion.
    Immunohistologic examination showed that the MALT lymphoma was positive for CD20, CD79α and bcl-2, and negative for CD3, CD5 and CD10.
    She felt mouth dryness. The left parotid gland was found to have become atrophic by MRI, and SS-A antibodies were noted on blood testing. Further, pathological tissue typical of Sjogren’s syndrome was noted in her salivary gland operatively.
    So a diagnosis of Sjogren’s syndrome was made, and MALT lymphoma was believed to have developed from Sjogren’s syndrome.
    There was no evidence of recurrence 12 months after the operation
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  • Masayuki Shibayama, Shigehiro Oowaki, Fumio Ogawa, Takeshi Shimizu
    2009 Volume 102 Issue 5 Pages 359-364
    Published: 2009
    Released on J-STAGE: March 03, 2011
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    A rare case of epithelial-myoepithelial carcinoma of the parotid gland in a 90-year-old woman is reported. The patient presented with a 7-year history of right-sided parotid gland swelling. Magnetic resonance imaging revealed a well-defined mass, measuring about 70 mm in diameter. The patient underwent parotidectomy with preservation of the facial nerves. The resected tumor showed characteristic histologic features: double-layered tubular structures composed of inner dark and outer clear cells. Although no additional treatment has been performed, the patient has remained free from recurrence for two years after the operation. The diagnosis and treatment of epithelial-myoepithelial carcinoma are discussed.
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  • Yukiko Yokoyama, Kazuhiko Yokoshima, Yuko Nakazawa, Kaoru Kusama, Sach ...
    2009 Volume 102 Issue 5 Pages 365-371
    Published: 2009
    Released on J-STAGE: March 03, 2011
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    Pyriform sinus fistula is a relatively rare disease that causes recurrent neck abscess. Radical treatment for this disease involves extirpation of the fistula; however, the physical and emotional stress caused by the surgery is sometimes not well tolerated by patients, especially small children. Thus, it is important to pursue the possibility of other trearment strategies. Recently, it is suggested that chemocauterization of the internal opening of the fistula is a safe and effective mode of management of pyriform sinus fistula.
    We reviewed four cases (two boys and two girls, aged 5 to 7 years) with pyriform sinus fistula treated with trichloroacetic acid (TCA) chemocauterization during the period from 2002 through 2007 at Nippon Medical School. By direct endoscopy, the opening of fistula in the left pyriform sinus was easily detected. There were no intraoperative or postoperative complications. In two of the four patients, it was not necessary to incise the neck to drain the abscess as they were managed with antibiotics and chemocauterization. Oral feeding was started within the first 2 days postoperatively. Only one of the four patients had a recurrent neck abscess, which was managed by extripation of neck granulation and repeated TCA chemocauterization.
    Our experiences suggest that TCA chemocauterization is a relatively safe, simple and useful mode of treatment for pyriform sinus fistula especially in children. The appropriate concentration of TCA, indications for using this mode of treatment and the long term prognosis remain to be determined.
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  • Taketoshi Nogaki, Yukiomi Kushihashi, Yoshiyuki Kadokura
    2009 Volume 102 Issue 5 Pages 373-377
    Published: 2009
    Released on J-STAGE: March 03, 2011
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    A 57-year-old male with a laryngeal saccular cyst is reported. The patient's chief complaint was hoarseness and an abnormal feeling in his throat.
    Fiberscopic examination demonstrated swelling of the false cord and laryngeal ventricle. CT and MRI showed a cystic lesion located on the right side of the vocal cord. The mass was removed completely by an external approach under general anesthesia. Based on clinical and histopathological findings, we diagnosed the disease as lateral saccular cyst. There has not been any sign of recurrence for 11 months since resection.
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  • Ken-ichi Kaneko, Koichi Sakaguchi, Masato Inoue, Fujinobu Tanaka, Atsu ...
    2009 Volume 102 Issue 5 Pages 379-384
    Published: 2009
    Released on J-STAGE: March 03, 2011
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    Observing vibration of the vocal folds is essential to find causes of hoarseness. We assembled the high-speed movie system from a consumer digital video camera (EXILIM PRO EX-F1, Casio Computer Co., LTD., Tokyo) and a conventional rigid laryngeal endoscope. This system enables us to observe each vocal fold vibration at a frame rate of 1,200 images per second. We examined the vocal folds of 10 healthy subjects and two patients with hemilateral vocal fold paralysis with our system. The high-speed movies were saved in the camera as MOV format files. On slow playback of the movies and kymographic images constructed from the movie files, the vocal fold vibrations of healthy subjects showed regularity, symmetry, complete glottal closure, normal amplitude and normal mucosal waves. However, those of the subjects with vocal fold paralysis showed irregularity, asymmetry, incomplete glottal closure, abnormal amplitude and abnormal mucosal waves. Our system will be useful for a routine clinical examination of the vocal folds.
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  • Yujiro Fukuda, Kouichi Watanuki, Yuji Imate, Hiroshi Yamashita
    2009 Volume 102 Issue 5 Pages 385-388
    Published: 2009
    Released on J-STAGE: March 03, 2011
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    Carotid body tumor is a relatively rare paraganglioma that arises from the carotid body. Preoperative evaluation is extremely important because this tumor adheres tightly to the carotid artery wall. A 57-year-old woman had an asymptomatic, slow-growing mass in the left neck. Magnetic resonance imaging showed a tumor at the carotid bifurcation causing displacement of the external and internal carotid arteries. Preoperative Matas test was carried out. Angiography did not show any major feeding artery, therefore embolization was not performed. Intraoperative findings did not detect any infiltration of the carotid arteries and the tumor was removed without clamping or injuring the carotid artery. Postoperatively, temporary paralysis of the glossopharyngeal nerve occurred. The patient was followed-up for 6 years postoperatively. There were no signs of local recurrence.
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  • Kousuke Yoshifuku, Tatsuya Fukuiwa, Tamon Hayashi, Jyunichirou Ohori, ...
    2009 Volume 102 Issue 5 Pages 389-393
    Published: 2009
    Released on J-STAGE: March 03, 2011
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    Anterior cervical fixation is a common surgical procedure for cervical instability, and complications are very rare. However, one major complication is implant loosening, which may cause dysphagia or even esophageal perforation.
    We report a patient with abnormal sensation of the larynx and esophageal perforation that occurred 18 years after reconstruction of the cervical spine using paramethoxymethamphetamine.
    A 72-year-old male had previously undergone reconstruction of the cervical spine using paramethoxymethamphetamine in 1990. He visited a hospital complaining of abnormal sensation of the larynx 18 years after the surgery. Gastric fiberscopy revealed a foreign body in the esophagus, and he was referred to our clinic.
    Although the patient had no local or general symptoms, CT scan showed paramethoxymethamphetamine coming out of the lumen of the cervical esophagus from its posterior wall. Video-fluorography revealed no esophageal stenosis.
    Based on these findings, the patient was diagnosed with late-onset esophageal perforation after the anterior cervical operation. The need to perform emergent surgery was explained to him, but he refused to undergo the surgery.
    He is now under careful follow-up at the out-patient clinic. So far, he has not complained of any pharyngeal or laryngeal symptoms.
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Original articles
  • —Comparison with Ménière’s Disease—
    Tamio Kamei
    2009 Volume 102 Issue 5 Pages 395-401
    Published: 2009
    Released on J-STAGE: March 03, 2011
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    Delayed endolymphatic hydrops (DEH) is a Ménière’s syndrome that typically occurs in patients suffering from longstanding unilateral profound inner-ear hearing loss. Approximately 55 to 65% of the hearing loss preceding DEH is due to juvenile unilateral profound deafness (early childhood unilateral profound sensorineural hearing loss of unknown etiology). The incidence of ipsilateral DEH (approximately 60%), in which the ear with profound hearing loss suffers progressive endolymphatic hydrops, is higher than that of the contralateral type of DEH (about 40%), in which the formation of progressive endolymphatic hydrops takes place in the ear opposite to the previously deafened ear. The prevalence of DEH in the general population (23 or less per 100,000) is similar to that of definitive Ménière’s disease, and the distribution of age at onset of DEH closely resembles that of Ménière’s disease except for some patients with childhood onset of DEH. Further, the rate of patients with the contralateral type of DEH (about 40%, although the rate is about 15% if the contralateral type is restricted to patients showing typical Ménière’s symptoms) is similar to that of patients with bilateral Ménière’s disease (about 40%, with a rate of about 14% if Ménière’s disease in the second ear is restricted to definitive Ménière’s disease). Since DEH is closely similar to Ménière’s disease not only in symptoms, but also in many clinical-statistical characteristics, the diseases may be identical in pathogenesis and the pathophysiology of progressive endolymphatic hydrops, although the two conditions have different etiologies.
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  • Atsushi Suehiro, Shin-ichi Kanemaru
    2009 Volume 102 Issue 5 Pages 403-410
    Published: 2009
    Released on J-STAGE: March 03, 2011
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    Cancer stem cells (CSCs) are a sub-population of cancer cells that are the main tumorigenic cells in tumors. These cells possess characteristics normally associated with stem cells. CSCs have stem cell properties such as self-renewal and the ability to differentiate into multiple cell types, therefore these cells are supposed to be derived from normal adult stem cells or progenitor cells. The cancer stem cell theory suggests that only CSCs within the tumor can self-renew and proliferate extensively to form new tumors. In several different types of cancer, it has been demonstrated that a distinct subset of cells initiates tumors in vivo, whereas the remaining cells do not. Development of flow cytometry, in vitro bioassay, and immunodeficiency mice have contributed to rapid progress in CSC research. CSCs were identified for the first time in human acute myeloid leukemia, in 1997. Thereafter, CSCs have been identified in breast cancer, brain cancer, colon cancer, and pancreatic cancer. As for the head and neck region, in 2007, Prince et al. reported that all cells that have tumorigenic potential were contained within the CD44Lin population in head and neck squamous cell carcinoma. To date, CSCs have not been found in thyroid cancer, or salivary cancer. Tumors often respond to chemotherapy initially, but frequently recur, suggesting that residual stem cells remaining after therapy are responsible for tumor recurrence. CSC-targeting chemotherapy should lead current cancer treatment to a new stage.
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