Practica Oto-Rhino-Laryngologica
Online ISSN : 1884-4545
Print ISSN : 0032-6313
ISSN-L : 0032-6313
Volume 107, Issue 6
Displaying 1-14 of 14 articles from this issue
Editorial
  • Tomokazu Yoshizaki
    2014 Volume 107 Issue 6 Pages 425-431
    Published: 2014
    Released on J-STAGE: June 01, 2014
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    During some 50 years of the debate regarding the association of allergic disease with cancer incidence, a growing number of epidemiological studies support the hypothesis that individuals with allergies have a lower risk of developing cancer. There is a particular and most constantly noted inverse correlation with glioma, pancreatic cancer, and childhood leukemia. There are also some studies that have reported that a history of allergic outbreaks reduces the risk of head and neck cancer. On the other hand, a history of atopic dermatitis is suggested to increase the risk of skin cancer, and a history of allergies increases the risk of developing nasopharyngeal carcinoma in endemic areas. In our study, total IgE levels and the positive rate of the RAST test were lower in oral and laryngeal cancer patients than nasopharyngeal carcinoma patients. Thus, the carcinogenic property of allergy-associated factors may be for site-specific events rather than for whole organs of the individual. Mast cells, a key player in allergic diseases, are also frequently detected around cancer cells. They are suggested to contribute to the progression of cancer. This review has shed light on the relevance of allergic diseases to cancer from the immunological viewpoint.
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Clinical color photographs
Original articles
  • Kousuke Furukawa, Suguru Matsumoto, Futoshi Watanabe
    2014 Volume 107 Issue 6 Pages 435-439
    Published: 2014
    Released on J-STAGE: June 01, 2014
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    Imaging diagnosis using magnetic resonance imaging (MRI) is indispensable for the diagnosis of acute cerebrovascular disturbances. Diffusion-weight imaging (DWI) MRI, in particular, has improved the diagnostic accuracy in acute ischemic stroke. However, some patients with acute stroke show no abnormal signals on DWI, despite the presence of an infarction. We present herein on a case of a hyperacute large ischemic stroke that was not detected on the initial DWI. A 85-year-old female with acute vertigo and vomiting was admitted to our hospital. In the neuro-otological examination, she had evoked direction fixed horizontal gaze and left-sided positional nystagmus. DWI examined within 2 hours after onset showed no ischemic findings. Twelve hours after onset, she developed consciousness disturbance and follow-up DWI demonstrated a large infarction on the brainstem, cerebellum and cerebrum.
    False-negative findings demonstrated on DWI are sometimes observed in the case of brainstem or cerebellar infarction. Careful observation of neurological findings and follow-up MR imaging are useful for closer investigation of false-negative findings in the patients with suspected as having suffered an ischemic stroke.
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  • Fumiko Kuboshima, Shin-ichi Kanemaru, Toshiki Maetani, Yoshihiro Tamur ...
    2014 Volume 107 Issue 6 Pages 441-446
    Published: 2014
    Released on J-STAGE: June 01, 2014
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    We reported herein on a case of bilateral epidural abscesses caused by subacute otitis media and mastoiditis.
    The patient was 61-year-old male with untreated diabetes mellitus. He complained of left retroauricular swelling, otorrhea and otalgia. Computed tomography (CT) scan and magnetic resonance imaging (MRI) showed bilateral epidural abscesses. Craniosurgical drainage was performed. After the operation, he was treated with intravenous antibiotics.
    Although otogenic intracranial complications are rare, they can still represent a serious condition. It is important to examine the head MRI findings, and to treat such conditions in the early stages of the disease.
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  • Chiaki Suzuki, Noboru Yamanaka
    2014 Volume 107 Issue 6 Pages 447-451
    Published: 2014
    Released on J-STAGE: June 01, 2014
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    Objective: To compare the clinical characteristics of bilateral acute otitis media (BAOM) with unilateral acute otitis media (UAOM) in children and to find risk factors of refractory otitis media.
    Patients and Methods: Four hundred and sixty-six children aged 0 to 14 years old (median age; 1 year old) with AOM were enrolled during January 2010 and June 2011.
    Diagnosis of acute otitis media, the severity classification by clinical/ontological scores, and treatments were based on Clinical Practical Guidelines for Acute Otitis Media in Children in Japan 2009. Refractory acute otitis media (RAOM) was designated as recurrent acute otitis media with more than 3 episodes in 6 months or more than 4 episodes in 12 months and/or persistent otitis media with a prolonged course of otitis media more than 3 weeks after the treatment. A multivariate logistic regression analysis was used to estimate the risk of BAOM and UAOM presenting with RAOM.
    Results: One hundred and thirty-seven (29.4%) patients were diagnosed as having RAOM. Two hundred and seventy-eight (60%) patients were diagnosed as having BAOM, 45.3% of whom had RAOM, whereas 11 (5.9%) of 188 patients with UAOM showed a refractory clinical course. One hundred and fifty-four (33%) patients were under 2 years of age and 71.3% of them had RAOM. The odds ratio for BAOM patients (compared with UAOM patients) to present with RAOM was 8.7 (95% confidence interval; 4.4–17.1). The odds ratio for patients under 2 years of age (compared with patients aged 2 or over) to present with RAOM was 7.1 (95% confidence interval; 4.4-11.8).
    Conclusions: BAOM patients and UAOM patients aged under 2 years of age were significantly associated with an intractable clinical course, and simultaneous occurrence of otitis media and an age under 2 years were apparent risk factors for refractory otitis media.
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  • Hideaki Tsuzuki, Kenzo Tsuzuki
    2014 Volume 107 Issue 6 Pages 453-462
    Published: 2014
    Released on J-STAGE: June 01, 2014
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    OBJECTIVES: Argon plasma coagulation (APC), performed as an outpatient procedure, is used to treat severe allergic rhinitis (AR) that is unresponsive to drug therapy. The purpose of this study was to determine the therapeutic effects of APC on patients with perennial AR (PAR) or seasonal AR (pollinosis), and to confirm complications after APC.
    METHODS: We performed bilateral APC under local anesthesia on 387 patients with PAR or Japanese cedar pollinosis at our clinic between November 2007 and August 2012. Postoperative changes in nasal symptoms including sneezing, nasal discharge and nasal obstruction, and intranasal findings were evaluated using a visual analogue scale (VAS) and the nasal grading score respectively, according to the Practical Guidelines for the Management of Allergic Rhinitis in Japan in 2013.
    RESULTS: In patients with PAR, the mean VAS scores of nasal symptoms improved in 6 months after APC. The severity of RAST scores to house dust, cauterized level, and nasal septum deviation did not show significant influence on the improvement of nasal obstruction after APC. In patients with pollinosis, the mean VAS score of nasal symptoms showed an improvement of 40-60% for one season after APC. Our data also indicated that the most proper time for APC in seasonal AR was for 2 months before the pollen dispersion. As regards to major postoperative complications, atrophy of the inferior turbinate (8%) and epistaxis (3%) were observed. The patients more than 40 years old and/or with RAST scores less than class 3 to house dust were found as significant high risk factors of inferior turbinate atrophy after APC.
    CONCLUSIONS: These results indicated that the APC is a useful treatment for patients with AR.
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  • Katsuya Fushimi, Kenzo Tsuzuki, Yusuke Kojima, Naoki Saka, Yasuo Mishi ...
    2014 Volume 107 Issue 6 Pages 463-468
    Published: 2014
    Released on J-STAGE: June 01, 2014
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    We report herein on two patients with severe epistaxis from the sphenoid sinus resulting in an unfortunate clinical course. A 67-year-old man presenting with severe epistaxis and headache was taken by an ambulance to our hospital. Epistaxis-impaired hemostasis from the sphenoid sinus was observed. The blood examination showed a high inflammatory reaction. Blepharoptosis, dysarthria, and disorientation occurred afterwards. Head magnetic resonance imaging (MRI) demonstrated a left internal carotid artery pseudoaneurysm projecting into the left sphenoid sinus. Endovascular coil embolization of the internal carotid artery to avoid serious hemorrhage was urgently performed after obtaining sufficient informed consent. Although hemostasis was maintained, extensive cerebral infarction occurred after the embolization. Finally the patient died from aspiration pneumonia 5 months after embolization.
    A 71-year-old man with epistaxis was transported by an ambulance to our hospital. He had a history of surgery and radiation therapy for chordoma. Pulsatile bleeding was observed from the remaining portion of the tumor in the posterior part of sphenoid sinus. He died of serious epistaxis with impaired consciousness after resuscitation attempt following cardiopulmonary arrest.
    In case of epistaxis from the sphenoid sinus, we should suspect that the internal carotid artery may be involved in the bleeding. A detailed medical history should be obtained, especially any neurosurgical interventions and/or radiation therapy for head and neck tumors. We should check the other symptoms such as cranial nerve symptoms. A blood examination also provides important information. Imaging, especially computed tomography (CT) and MRI, should be performed to check for any lesions surrounding the sphenoid sinus.
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  • Hiromi Nagano, Hiroyuki Iuchi, Tomohiro Jimura, Masaki Kawabata, Yuich ...
    2014 Volume 107 Issue 6 Pages 469-473
    Published: 2014
    Released on J-STAGE: June 01, 2014
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    The symptoms of adult T-cell leukemia (ATL) appear owing to an adult-T-cell-leukemia virus (humanT-cell leukemia virus type I: HTLV-1).
    A 91-year-old woman presented to the ENT service with a one-month history of hoarseness and an abnormal sensation of the throat. Inspection of the oral cavity revealed the presence of a tumor in the oropharynx. On endoscopic examination, the tumor extended from the nasopharynx to the oropharynx. A positron emission tomography/computed tomography (PET/CT) scan showed multiple accumulation throughout the body other than Waldeyer’s Ring. Histological analysis showed a variety of cells, which stained positive for CD3, CD4, CD8, and CD25, and negative to CD20.
    Taking those findings into consideration, we diagnosed the patient as having adult T-cell leukemia-lymphoma (lymphoma type).
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  • Ken-ichi Hisamatsu, Itsuhiro Kudou, Tomoyuki Takane, Kiyoshi Makiyama
    2014 Volume 107 Issue 6 Pages 475-482
    Published: 2014
    Released on J-STAGE: June 01, 2014
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    Objectives and Methods: Twenty four severe obstructive sleep apnea syndrome (OSAS) patients, 35 sleep disordered breathing (SDB) patients with excessive daytime sleepiness, and 74 simple snorers underwent coblation-assisted uvulopalatopharyngoplasty (cobUPPP) under local anesthesia. Polysomnography (PSG) events, snoring, QOL (SF-36 v2) and excessive daytime sleepiness on the Epworth sleepiness scale (ESS) were assessed 3 months after the operation. The overall assessment criteria of the operative effectiveness on OSAS were proposed using subjective symptoms and PSG events. Informed consent was obtained in writing from all participants prior to cobUPPP.
    Results: AI (P<0.0001), AHI (P<0.0001), ODI (P<0.0001), minimum SpO2 (P=0.028), SpO2<90% (P=0.008) and the arousal index (P=0.001) were significantly ameliorated. Excessive daytime sleepiness was ameliorated in 34/35 cases and bothering snoring was improved, based on visual analog scale scoring, in 54/55 cases. Treatment of OSAS was assessed as highly effective in 11/24, 9/24 effective and 4/24 ineffective. Transient discomfort of the pharynx was an occasional complaint.
    Conclusion: cobUPPP was effective for severe OSAS without significant complications and could be very useful to manage excessive daytime sleepiness and socially unacceptable snoring.
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  • Koichiro Yamada, Yohei Kumabe, Shinzo Tanaka, Yasuyuki Hiratsuka, Yosh ...
    2014 Volume 107 Issue 6 Pages 483-488
    Published: 2014
    Released on J-STAGE: June 01, 2014
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    Synchronous parotid tumors are rare. Unilateral, synchronous tumors of different histological types are very unusual. We report herein on a case of Warthin’s tumor and pleomorphic adenoma arising in unilateral parotid gland.
    A 54-year-old man presented with two masses in the right parotid gland. The preoperative magnetic resonance imaging revealed two tumors; one with a diameter of 30 mm in the infra-auricular region and the other with a diameter of 10 mm in the preauricular region. Fine needle aspiration showed the tumor in the infra-auricular region was compatible with Warthin’s tumor. Preoperative diagnosis was multiple Warthin’s tumors. The patient underwent surgical treatment under general anesthesia. The tumor in the infra-auricular region was resected by enucleation, the other in the preauricular region was resected by a partial superficial parotidectomy with preservation of the facial nerve. Pathologically, the diagnosis based on the resected specimens showed that Warthin’s tumor and a pleomorphic adenoma were coexisting in the right parotid gland. The patient is alive with no facial palsy or tumor recurrence at the latest follow-up, two years after the surgery.
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  • Haruka Tanaka, Keiji Tabuchi, Bungo Nishimura, Masahiro Nakayama, Akir ...
    2014 Volume 107 Issue 6 Pages 489-492
    Published: 2014
    Released on J-STAGE: June 01, 2014
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    We report herein on a case of antiphospholipid syndrome with the thrombosis of the internal jugular vein. A 34-year-old female presented to our department with right-side neck pain. Contrast enhanced computed tomography (CT) revealed enlargement of the right internal jugular vein, with a non-enhancing filling defect in the lumen and peripheral enhancement of the vessel wall, leading to a diagnostic of thrombosis. Additionally, serum lupus anticoagulant tested positive, thus, the diagnosis of antiphospholipid syndrome was confirmed. Subsequently, the patient was treated with intravenous antibiotics, intravenous heparin and oral warfarin. Her swelling and pain resolved slowly and she was discharged on warfarin. Follow up at 7 months has revealed no recurrence of her symptoms but persistence of her levels of lupus anticoagulant. We should be aware of the possibility of antiphospholipid syndrome in the management of thrombosis of the internal jugular vein.
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Original articles
  • Kohei Kawamoto, Shigeki Kawamura, Mikiya Asako, Koichi Tomoda
    2014 Volume 107 Issue 6 Pages 493-498
    Published: 2014
    Released on J-STAGE: June 01, 2014
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    Septoplasty is one of the frequently performed surgical procedures among nasal surgeries. Sometimes suture of the mucosa of the nasal septum is necessary and useful to prevent mucoperichondrial flap perforation or hematoma. Because the mucoperichondrial flap has little tension once peeled from the septum, suturing is not technically easy. We used a Maniceps® Septum Stitch, a semiautomatic suturing device, for nasal surgery. This system was originally developed as laparoscopic suture system and was modified for nasal surgery. The system comprises a pair of forceps: a straight needle is set on a needle holder which can pass the suture through the target tissue with one motion (closing and reopening the forceps). The semiautomatic suturing system is useful to not only for suturing of the nasal septum, but also for suture medialization of the middle turbinate to the septum in endoscopic sinus surgery.
    When using the Maniceps® Septum Stitch in the deep nasal cavity, sometimes a needle mounted at the tip of the forceps can accidentally damage the mucosa. In order to prevent such damage, we put a magnet at the side of the tip which can hold the needle parallel to the forceps. This ingenious little addition makes it easier to handle the system in the deep nasal cavity. We report herein on the practical usefulness of this semiautomatic suturing device in the nasal surgery along with the presentation of some cases, and conclude that the system makes suturing techniques in the nasal cavity easier to some extent.
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Technical notes
Medical essays
  • —Part 11. Trousseau and Stomachic Vertigo—
    Toshitaka Iinuma
    2014 Volume 107 Issue 6 Pages 503-507
    Published: 2014
    Released on J-STAGE: June 01, 2014
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    Stomachic vertigo was originally recognized as being of both ancient and classical origin, but fell into oblivion around the middle of the 19th century. Despite this, it is still of academic interest how the ideas of vertigo evolved from eminent ancient and classical scholars. Theophrastus (371-287 B.C.) published a small monograph entitled “vertigo” in which simple vertigo, tenebrous vertigo, and stomachic vertigo were mentioned. Trousseau was very interested in stomachic vertigo, and he gave lectures repeatedly to general practitioners. French has an amazing cultural custom in preserving classical data and medical dictionaries are no exception. Paying our respect, we were happy enough to go through the medical dictionaries from the 17th to 19th centuries, focusing our interest on vertigo. We noticed the decline of stomachal vertigo after the acceptance of Menière’s idea of vertigo.
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