In their report, Ibrahim et al. described that generating platinum chloroquine diphosphate dichloride (PtCQ)-loaded polyethylene glycol (PEG)-modified (PEGylated) cationic liposomes exhibiting high drug encapsulation and high drug retention. PtCQ was encapsulated in PEGylated cationic liposomes comprising various amounts of cationic lipids using the remote-loading method. PEGylated neutral liposomes and cationic liposomes exhibited minimum leakage of PtCQ after two months’ storage at 4˚C, and further exhibited little release under in vitro culture conditions at 37˚C for 72 hours. These results provide a useful framework for the design of future liposome-based in vivo drug delivery systems targeting the drug-resistant malaria parasite.