Background : Although unintentional weight loss is a frequently encountered problem in care settings, little is known about when it starts. The authors observed body weight longitudinally in an elderly population and examined its association with mortality. Methods : Body weight was monitored in residents who lived in a nursing home for the elderly in Tokyo between fiscal years 2002 and 2004, with the final observation date set at October 2008 for survivors and at the date of death for those who died. The 3-year period before the final date was divided into six periods. A linear regression coefficient was calculated as the rate of weight change for each period and compared between survivors and those who died. Results : In the mortality group, significant weight loss was seen from 24 months before death : -0.42kg, -0.62kg, -0.90kg, and -1.78kg in 19-24 months, 13-18 months, 7-12 months, and 1-6 months before death, respectively. In the survival group, there was no significant change in any period. Logistic regression analysis showed that weight change adjusted by sex, age, dementia, and BMI was significantly associated with mortality. The weight loss was large in residents with dementia. Conclusions : Weight loss began 2 years before death. The findings suggest the importance of daily weight measurements to detect changes associated with mortality.
Background & Aims : De Quervain's disease is known as a representative disease that causes wrist pain, however, its epidemiology remains unclear. The purpose of this study was to elucidate the prevalence of de Quervain's disease among the general population and to identify its risk factors. Methods : The subjects participated in the examinations consisted of 402 people (total of 804 hands), including 157 males and 245 females with mean age of 64.1 years. We recorded the subjects' background and medical history and then performed physical examinations. We determined the prevalence of de Quervain's disease and conducted a statistical analysis to investigate their background factors. Results : De Quervain's disease was present in 3.7% (15/402 people) and the prevalence by age group was 9.8% in their forties, 3.6% in their fifties, 1.8% in their sixties, 3.9% in their seventies, and 3.7% in their eighties. The prevalence was significantly higher in females than in males. No difference was found in terms of the mean age, hand dominance, height, weight, heaviness of labor activity and presence of medical complication. Conclusions : In the general population, 3.7% of 402 people had de Quervain's disease, and its risk factor was identified to be females.
Purpose : The aim of this study was to compare non-contrast 3T renal MRA with that of 1.5T unit. Methods and Materials : We performed renal MRA in twelve volunteers using a 1.5T and 3T unit. For renal MRA, 3D SSFP sequence was used. For quantitative evaluation, ROI was set on the aorta, main stems of bilateral renal arteries, and IVC, measuring flow signal at each point. Signal intensity ratio (SIR) of renal artery relative to the parenchyma and IVC were calculated. For subjective analysis, two readers evaluated visual quality. Results : SIR of the both renal artery on 3T MRA were significantly higher than those on 1.5T (p<0.01). On subjective analysis, the mean visualization score of renal main stem showed no statistically significant difference. However, the scores of the peripheral branches on 3T was significantly higher than those of 1.5T bilaterally (p<0.05). IVC showed significantly lower signal ratio on 3T relative to that on 1.5T. Conclusion : 3T MRA showed superior demonstration of renal arteries compared with 1.5T MRA. The intraparenchymal peripheral branches are especially well demonstrated on 3T MRA. Decreased venous signal on 3T system contributed to the selective arterial demonstration.
A 53-year-old man was admitted to our hospital because of lumbago. Gastrointestinal endoscopic examination performed on admission did not reveal any gross gastric abnormalities. Lumbar radiography and bone scintigraphy revealed multiple bone osteoblastic changes. Chest radiography showed right pleural effusion. The findings of the chest computed tomography and cytological examination of the pleural effusion were strongly suggestive of lung cancer. The patient was refractory to chemotherapy, and he died of cancer and disseminated intravascular coagulation. The autopsy revealed absence of primary lung cancer and the presence of tumor emboli in the right lung field. Swollen perigastric lymph nodes, tiny signet-ring cell carcinoma at the posterior wall of the stomach corpus, and severe vascular invasion were also observed at autopsy. Therefore, signet ring cell carcinoma of the stomach should be considered as a possible diagnosis in early-stage gastric cancer patients who develop osteoblastic metastasis and pleural effusion.