The Nishinihon Journal of Dermatology
Online ISSN : 1880-4047
Print ISSN : 0386-9784
ISSN-L : 0386-9784
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Volume 47, Issue 3
Displaying 1-24 of 24 articles from this issue
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Color Atlas
Mini Review
Clinical Case Reports
  • Spindle Cell Squamous Carcinoma Treated with Mohs’ Chemosurgery (Fixed Tissue Technique)
    Mariko SEISHIMA, Kazufumi YONEDA, Shunji MORI, Yasuo KITAJIMA
    1985 Volume 47 Issue 3 Pages 429-433
    Published: June 01, 1985
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.47.429
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    An 89-year-old woman with spindle cell squamous carcinoma treated with the modified technique of Mohs’ chemosurgery had a dome-like, elevated tumor on the right cheek. Histologically, the tumor consisted of atypical spindle-shaped cells. The lesion was treated with the paste composed of zinc starch, glycerin and a saturated solution of zinc chloride. After the lesion was fixed with this treatment, the tumor was shaved with a scalpel and the resected tissues were also histologically examined to confirm the complete removal of tumor cells. There has been no recurrence for one year after this treatment.
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  • Malassezia Folliculitis
    Tatsufumi YAMANO, Tadahiko MATSUMOTO, Harukuni URABE
    1985 Volume 47 Issue 3 Pages 434-439
    Published: June 01, 1985
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.47.434
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    Clinical, histopathologic, and mycologic studies of a series of patients with Malassezia folliculitis were performed during the period from July to September of 1984. Treatment of Malassezia folliculitis in two patients was effective when ketoconazole was given orally. Our findings in nine cases and a review of the seven occurrences in other Japanese revealed that Malassezia folliculitis is a rather common, occasionally mis-diagnosed disease, and should be differentiated from steroid acne and acne aestivalis. We propose “Malassezia folliculitis”, rather than Pityrosporum folliculitis, as an appropriate term for this disorder, as based on the current taxonomic concept of the causative microorganism: Malassezia furfur (Robin) Baillon.
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  • Three Cases of Basal Cell Epithelioma with Unusual Clinical Features
    Shigehito INOUE, Sakar KIMURA, Yasutaka IWAHORI, Tatsutaka FURUYA
    1985 Volume 47 Issue 3 Pages 440-445
    Published: June 01, 1985
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.47.440
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    We treated three patients with basal cell epithelioma and almost the same unusual clinical features, but with typical histological findings. The unusual clinical features of these tumors included 1) nodular (dome-shaped, or slightly polypoid), 2) non-ulcerated, 3) elastic soft and 4) variously pigmented findings. Because of these clinical features, it was difficult to make a correct diagnosis at the first examination.
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  • Sézary Syndrome Formed a Giant Tumor on the Skin
    Yutaka NARISAWA, Yoshikado SAKAZAKI, Masayoshi JONO, Hiroshi KATSUKI
    1985 Volume 47 Issue 3 Pages 446-452
    Published: June 01, 1985
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.47.446
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    We treated a 43-years-old Japanese woman with Sézary syndrome, in whom a giant tumor (similar to those usually observed in the tumor stage of mycosis fungoides) formed about three years later. Clinical appearances, histopathological and electron microscopic findings, and immunological studies were discussed.
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  • Cutaneous T Cell Lymphoma with Squamous Cell Carcinoma on Nasal Mucous Membrane
    Kanji KITADE, Kiyotaka KONISHI, Sumiko ICHIKAWA, Yoshiki TANIGUCHI, Hi ...
    1985 Volume 47 Issue 3 Pages 453-458
    Published: June 01, 1985
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.47.453
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    A case of cutaneous T cell lymphoma with squamous cell carcinoma on the nasal mucous membrane is reported herein. In a 51-year-old man, a flesh colored papulo-nodular skin lesion was disseminated over his entire body. Axillary and inguinal lymphadenopathy but no hepatosplenomegaly were present. A specimen from the skin lesion revealed diffuse infiltration of large atypical lymphocytes to dermis and subcutanous tissue, without epidermal infiltration. The specimen from the axillary lymphnode also revealed diffuse infiltration of large atypical lymphocytes. No atypical cell was found in peripheral blood or bone marrow puncture. Surface markers of the lymphoma cells showed E-rosette formation (+), OKT3 (+), OKT4 (+), OKT8 (-) and OKIa (+). The patient complained of nasal obstruction. At the time of local nasal examination, a small nodule was found in the left nasal membrane. The specimen from the nasal nodule showed well differentiated squamous cell carcinoma.
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  • Angioma Serpiginosum
    —Case Reports of Three Patients and Characterization of the Capillaries—
    Kensei KATSUOKA, Yusuke SUZUKI, Ichiro KATO
    1985 Volume 47 Issue 3 Pages 459-464
    Published: June 01, 1985
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.47.459
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    Three patients with the diagnosis of angioma serpiginosum were treated. One was a rare case in a 15-years-old boy with generalized angioma serpiginosum. We studied the characteristics of the capillaries using electron microscopy, alkaline phoshatase staining and localization of factor VIII related antigen. We concluded that this disease is characterized by dilatation and proliferation of the capillaries.
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  • Dermatomyositis Associated with Subcutaneous Nodules
    Masami ARAKAWA, Yoji TAKEI, Hiroaki UEKI
    1985 Volume 47 Issue 3 Pages 465-468
    Published: June 01, 1985
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.47.465
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    We treated a woman with dermatomyositis and subcutaneous nodules. The migratory subcutaneous nodules were thumb-tip in size and she complained of slight pain in the adbomen and extremities. The nodules seem to move about spontaneously, but there were no resultant scars.
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  • Lichen Myxoedematosus
    Yoshihiro MAEKAWA, Toshitatsu NOGITA
    1985 Volume 47 Issue 3 Pages 469-473
    Published: June 01, 1985
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.47.469
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    Lichen myxoedematosus was diagnosed in a 46-year-old woman and 62-year-old man. The woman had generalized lichenoid papular eruptions with severe itching on her head, face, back and hands. The laboratory findings disclosed a thrombocytopenia with no tendency toward bleeding. There seemed to be no relationship between these papular eruptions and the thrombocytopenia. The man had discrete papular eruptions on his forearms and as lung cancer was also evident, the eruptions suggest a dermadrome of the lichen myxoedematosus.
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  • Myrmecia on the Wrist
    Akio YAMAMOTO, Hajime MIKOSHIBA
    1985 Volume 47 Issue 3 Pages 474-481
    Published: June 01, 1985
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.47.474
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    A 12-year-old girl complained of a reddish, painful tumor on the flexural side of the right wrist, and which had grown gradually during the past 4 weeks. The tumor was surgically excised and histopathologically, the tissues revealed hyperparakeratosis, acanthosis and papillomatosis. The eosinophilic intracytoplasmic and intranuclear inclusion bodies appeared first in the cells in the deep portion of the stratum spinosum and the size was larger in the upper portion. The nuclei in the clear cells in the middle to upper portions of the stratum spinosum possess basophilic inclusion bodies. There was no actual stratum granulosum. The nuclei in the stratum corneum appeared as deeply basophilic, round to oval bodies. Electron microscopically, the eosinophilic bodies were recognized as sharply defind, osmiophilic bodies and which did not belong to viral inclusion bodies. The basophilic bodies revealed numerous viral particles within and around the nucleoli. In the stratum corneum, the viral particles were closely packed and pseudocrystalline formations were evident within the aggregate.
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  • DLE-like Eruption Induced by Futraful
    Yukihiro OKUMURA, Yumiko MIYAWAKI, Hiroshi KUWAHARA, Toshiro KAGESHITA
    1985 Volume 47 Issue 3 Pages 482-484
    Published: June 01, 1985
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.47.482
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    We treated a 59-year-old man who had clinical and histological evidence of DLE-like eruption on the sun-exposed sites, such as face, chest and forearm while on oral administration of Futraful for a metastatic cancer of the liver. Direct immunofluorescence showed a linear deposition of only fibrinogen in the dermoepidermal basement membrane zone. Serological results were negative.
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Clinical and Investigative Report
  • Cell-Mediated Immunity in Experimental Dermatophytosis on Guinea Pigs
    Shingo ONISHI
    1985 Volume 47 Issue 3 Pages 485-495
    Published: June 01, 1985
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.47.485
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    Guinea pigs infected with Trichophyton mentagrophytes were studied weekly after inoculation for cell-mediated immune responses, including delayed intractaneous skin test, macrophage migration inhibition test (MIT) and patch test. In the intracutaneous skin test with purified trichophytin consisting polysaccharide, positive reactions occurred in 3 out of 8 animals one week after the inoculation. All 14 animals were positive at two weeks, 3 of 6 animals were negative at 24 weeks after the inoculation. Positive skin reaction persisted for one year after the inculation, in some animals. For the MIT we used the same purified trichophytin. All 8 animals were negative at one week, 7 of 14 animals were positive at two weeks, 5 out of 6 animals were positive at 4 weeks and only one of 6 was positive at 24 weeks after the inoculation. MIT positive animals also revealed a positive skin reaction. Patch test with crude trichophytin showed histologically mild hyperkeratosis and sparse cell infiltration of mononuclear cells and neutrophils in the upper dermis one week after inoculation. Two weeks after inoculation, basal spongiosis and moderate cell infiltration of mononuclear cells, neutrophils and a few eosinophils were seen in the upper dermis. Three weeks after inoculation and thereafter, neutrophilic subcorneal pustules resembling Kogoj’s spongiform pustule in psoriasis pustulosa, dense and diffuse cell infiltration consisting of numerous mononuclear cells and neutrophils, and some eosinophils in the whole dermis were seen. These observations were evident even one year after the inoculation in those animals with a positive skin reaction, but never in those with a negative skin reaction. In guinea pigs, these results indicate that cell-mediated immunity was established two weeks after inoculation of T. mentagrophytes, and thenafter positive intracutaneous skin test responded positive reaction of MIT and patch test.
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Review
Statistics
  • Clinical Studies on Cutaneous Vasculitis
    Part II: Clinical Course and Prognosis on Vasculitis Allergica Cutis
    Ichiro KATO, Ryuzo SAITO
    1985 Volume 47 Issue 3 Pages 504-508
    Published: June 01, 1985
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.47.504
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    Twelve patients with vasculitis allergica cutis were treated in our department from 1971 to 1983.
    1) The occurrence was more frequent in adult females.
    2) Histopathologically, there was evidence of necrotizing vasculitis of small vessels with various rashes.
    3) Transient inflammatory reactions in the general examination occurred in some patients, however, severe immunological abnormalities were not observed.
    4) The prognosis was good and generalized organopathy did not occur. The rash healed within 6 months, in most cases.
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  • Periungual Erythema in Connective Tissue Diseases
    Tomoko OTA, Daisuke OKA, Hiroaki UEKI
    1985 Volume 47 Issue 3 Pages 509-514
    Published: June 01, 1985
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.47.509
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    We examined periungual erythema in 143 patients with various connective tissue diseases, 6 patients with Raynaud’s syndrome and 30 disease-free subjects. Clinically, periungual erythema consists of erythema, telangiectasia and bleeding. Periungual erythema was found in 100% of patients with dermatomyositis (DM), in 77% with mixed connective tissue disease (MCTD), in 63% with progressive systemic sclerosis (PSS), in 50% with systemic lupus erythematosus (SLE) and in 83% with Raynaud’s syndrome. This erythema was absent in the disease-free subjects. SLE and localized discoid lupus erythematosus (1. DLE) tended to be accompanied by erythema, while PSS, DM, and MCTD related more to telangiectasia. The majority of PSS with Raynaud’s phenomenon was found to have periungual erythema, while it was rarely seen in cases of SLE with Raynaud’s phenomenon. Capillaroscopic findings of the nail fold disclosed a scleroderma (SD) pattern, a lupus erythematosus (LE) pattern, a normal pattern and a nonspecific pattern, according to Minkin’s classification. The SD pattern was frequent in PSS, DM and MCTD, while the LE pattern was frequent in cases of SLE and 1. DLE. Capillary abnormality occurred in 6% of disease-free subjects. We thus regard periungual erythema as an important sign of connective tissue disease.
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  • Statistical Study on Bacteria Isolated from Infectious Foci on the Skin from 1977-1982 in the Department of Dermatology, Kansai Medical University
    Setsuko NISHIJIMA, Mitsuko NAKAGAWA, Yasuo ASADA
    1985 Volume 47 Issue 3 Pages 515-519
    Published: June 01, 1985
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.47.515
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    A statistical study was done on 638 strains of bacteria, isolated from infectious foci on the skin, from 1977-1982 in the Department of Dermatology, Kansai Medical University. The most frequently isolated strain was Staphylococcus aureus, followed by Staphylococcus epidermidis and gramnagative bacilli, in this order. There was no great change in the bacterial species isolated during these 6 years. Concerning Staphylococcus aureus and Staphylococcus epidermidis, attention was directed to susceptibillity to antibiotics and to single or multiple isolation. Staphylococcus aureus was often isolated singly, while Staphylococcus epidermidis was more often isolated from the focus of mixed infection, but has recently increased in cases of single isolation. The susceptibilities of Staphylococcus aureus to PCG, EM, OL, CLDM, KM, and ABPC decreased gradually during these 6 years, the rate now at less than 50%. In contrast, Staphylococcus epidermidis showed no great changes, except for PCG and KM.
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  • Incidence of Clavi
    Atsuko KIMURA, Hiroto KOBAYASHI, Shunei TANABE, Hiroshi ISHIZAKI, Yone ...
    1985 Volume 47 Issue 3 Pages 520-522
    Published: June 01, 1985
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.47.520
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    In a combined study of 925 inpatients (500 males, 425 females) all over 20 years of age and admitted to Kanazawa Medical University Hospital and Kurobe City Hospital, the incidence of clavi was 5.6% in males and 7.5% in females. Mean age of males with clavi was 61.4 and significantly higher as compaired with that of controls (0.01<P≤0.05). Incidence of clavi in females in the third decade of life was 13.7%, which was significantly higher than in the other decades.
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Therapy
Dermatologists around the World
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