A 69-year-old woman developed erythema on the inside of her left femoral in March 2006. She visited a dermatology clinic and was diagnosed with erysipelas. However, since response to the therapy was poor, she was referred to our hospital. Physical examination revealed erythema and painful swelling from the pubic region to the left femoral, and an erosion 1cm in diameter on the anterior surface of the left femoral. Laboratory findings revealed leukopenia. Histopathologically, medium and large irregularly-shaped lymphocytes were invading into the subcutaneous tissue. Immunohistochemically, the tumor cells were positive for CD3, CD8, CD45RO, and granzyme B, but were negative for CD4, CD5, CD10, CD20, CD23, CD56, CD79
α, and myeloperoxidase. A diagnosis of subcutaneous panniculitis-like T-cell lymphoma was made, and as a consequence, she was treated with systemic chemotherapy (Hyper-CAVD). However, only 21 days after the initial visit, she died from sepsis with multiple metastasis. An autopsy revealed complication of hemophagocytic syndrome (HPS).
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