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Volume 72, Issue 1
Displaying 1-14 of 14 articles from this issue
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Color Atlas
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Atsushi HOSOKAWA, Sayaka YAMAGUCHI, [in Japanese], Hiroshi UEZATO2010 Volume 72 Issue 1 Pages 1-2
Published: February 01, 2010
Released on J-STAGE: May 14, 2010
JOURNAL RESTRICTED ACCESSDownload PDF (1389K)
Clinical Case Reports
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Atsuko IBUSUKI, Hiroshi UCHIMIYA, Shigeto MATSUSHITA, Kazuhiro KAWAI, ...2010 Volume 72 Issue 1 Pages 3-5
Published: February 01, 2010
Released on J-STAGE: May 14, 2010
JOURNAL RESTRICTED ACCESSWhile a number of patients with contact dermatitis to antimicrobial coatings of desk mats have been reported recently, we encountered a patient with contact dermatitis to a desk mat without an antimicrobial coating. A 48-year-old woman, an office worker, had suffered from erythematous lesions on her bilateral forearms and hands for 8 years. Her skin lesions were present periodically from the end of June to November in every year. Her forearms were exposed during this period because she usually wore short-sleeved shirts. Since she used a desk mat in her daily work, we considered the possibility of contact dermatitis to a desk mat. Patch testing with her own desk mat, ‘as is’, showed a positive reaction. The desk mat was not treated with an antimicrobial coating and contained 5 ingredients : Polyvinyl chloride, plasticizer (dioctyl phthalate), epoxidized linseed-oil, methylene-bis-stearylamide, and a “metallic soap stabilizer,” according to the manufacturer. The company provided us with these ingredients. Although 4 ingredients were exactly identical to those used in the desk mat, the metallic soap stabilizer was substituted with similar material because production of this stabilizer was discontinued. The provided stabilizer consisted of barium and zinc and has a molecular structure that is close to that of the original one. We performed a patch tests with these 5 ingredients, and only the metallic soap stabilizer produced an allergic reaction. Patch testing with the stabilizer in 7 control subjects was negative. Based on these results, we concluded that her skin lesion was contact dermatitis due to the stabilizer contained in the desk mat that was not treated with an antimicrobial coating. Our review of the previous literature uncovered no report of such cases. This case demonstrates the risk of contact sensitization to stabilizers that are widely used in daily life.View full abstractDownload PDF (1137K) -
A Case ReportAkitaka SHIBATA, Akinori HAYAKAWA, Teruyuki MITSUMA2010 Volume 72 Issue 1 Pages 6-10
Published: February 01, 2010
Released on J-STAGE: May 14, 2010
JOURNAL RESTRICTED ACCESSWe report the case of a 55-year-old woman with scleroderma who developed anti-neutrophil cytoplasmic autoantibody-related renal failure. She was diagnosed as scleroderma in 2000 by the episodes of Raynaud's phenomenon, skin thickness and pulmonary fibrosis. From May of 2007, her anemia gradually progressed, and her renal function gradually deteriorated. Because her anemia and renal function were getting worse in August, she was admitted to our hospital for investigation. The myeloperoxidase-specific anti-neutrophil cytoplasmic antibody (MPO-ANCA) concentration was found to be elevated to over 500 EU/ml. Histological examination of a renal biopsy showed necrotizing crescentic glomerulonephritis. We diagnosed her as ANCA-related Crescentic Glomerulonephritis. Methylprednisolone pulse therapy was started, followed by oral prednisolone (30mg/day). MPO-ANCA rapidly decreased, and her renal function improved. In the course of scleroderma or pulmonary fibrosis, when fever and renal dysfunction occur without malignant hypertension, bloody phlegm or purpura, the serum MPO-ANCA concentration should be measured.View full abstractDownload PDF (1301K) -
Kaori SUETSUGU, Mami TAJIMA, Masashi YAMAZAKI, Yoshihiko MITSUHASHI, R ...2010 Volume 72 Issue 1 Pages 11-14
Published: February 01, 2010
Released on J-STAGE: May 14, 2010
JOURNAL RESTRICTED ACCESSWe report the case of a 37 year-old man who developed Sweet's syndrome while receiving Highly Active Anti-Retroviral Therapy (HAART) for the treatment of HIV infectious disease. HAART was initially begun seven years ago, but was terminated for a period due to side-effects, then restarted 1 year and 4 months prior to consultation. Three months after the therapy was restarted, the patient developed a rash with fever, a feature that was similar to the presented episode; this first episode improved without any treatment. One week prior to his first visit to our outpatient clinic, the patient developed erythema with tenderness on the left side of his neck, a fever of 40°C, and arthralgia of the right knee and ankle. A physical examination revealed two erythematous plaques with raised peripheries on the left side of the neck. Blood examination showed a leukocyte count of 10800/μl, and neutrophils at 79.8%, CRP 13.4mg/dl. Histopathological examination revealed intense infiltration mainly of neutrophils with leukocytoclasis and lymphocytes in the dermis. After oral administration of prednisolone 20mg/day, the erythema and arthralgia disappeared with no recurrence. In our case, Sweet's syndrome developed twice during the administration of HAART. We speculate that the onset of Sweet's syndrome may be related to an increase in the number of CD4+ lymphocytes caused by HAART. This is the first report in Japan of Sweet's syndrome with HIV infectious disease.View full abstractDownload PDF (1201K) -
Yukichika ISHII, Nagako HORIKAWA, Mitsuru SETOYAMA, Tadashi MIIKE, Mot ...2010 Volume 72 Issue 1 Pages 15-19
Published: February 01, 2010
Released on J-STAGE: May 14, 2010
JOURNAL RESTRICTED ACCESSA 66-year-old woman had noticed purpura on her lower legs for two months. The lesion had gradually enlarged during one month. She presented at our hospital with large annular purpuric plaque, painful knees and bloody diarrhea. A skin biopsy showed a leukocytoclastic vasculitis, but no deposition of IgA in dermal vessels was recognized with a direct immunofluorescence test. Simultaneously, it was disclosed with colonoscopy and mucosal biopsies that she had ulcerative colitis, which was then treated with oral prednisolone and sulfasalazine. After the administration, diarrhea, skin lesions and joint pain improved completely. To the best of our knowledge, only 9 cases of ulcerative colitis associated with cutaneous leukocytoclastic vasculitis developing unusually large annular purpuric plaque have been reported.View full abstractDownload PDF (1732K) -
Hiroyuki KAYO, Yuichi YAMAMOTO, Yuko HANNITA, Ayano NAKAMATSU, Misao T ...2010 Volume 72 Issue 1 Pages 20-25
Published: February 01, 2010
Released on J-STAGE: May 14, 2010
JOURNAL RESTRICTED ACCESSAn 80-year-old Japanese woman presented a black tumor that extended from the sole to the lateral margin of the right foot. It had a dimension of 95 × 55 × 38 mm, was pedunculated and protruded upward like a cauliflower. The histopathological diagnosis of the tumor was malignant melanoma. She was treated with wide local excision of the tumor, full thickness skin graft, and dissection of lymph nodes in the right inguinal area under general anesthesia. CT and histopathological examination showed no metastases to the lymph nodes or distant organs. Therefore, the stage was classified as III A (in AJCC : stage-II C, T4bN0M0). After that she was given local injection of interferon-β. She was well for 3 years and 10months after the operation without regional recurrence or metastases to the lymph nodes or other organs. But she died from lung adenocarcinoma. We also present a brief summary of all the reported cases of pedunculated malignant melanoma in Japan.View full abstractDownload PDF (1530K) -
Kyoko KUDO, Fumiko YASUKAWA, Kazunori URABE, Seiya MOMOSAKI, Reiko KAW ...2010 Volume 72 Issue 1 Pages 26-30
Published: February 01, 2010
Released on J-STAGE: May 14, 2010
JOURNAL RESTRICTED ACCESSA case of a mixed tumor of the skin on the upper lip of a 40-year-old man who had had it for 15 years is reported. It had developed to 15 mm in diameter and contained hypopigmented spots. We initially thought it was a follicular adnexal tumor and resected it. The histological examination revealed a thickened epidermis with hyperkeratosis and papillomatous changes. In addition, large and small nests became apparent with the decapitation in some glands and stroma with myxomatous and fibromatous changes. Immunohistochemical staining provided a diagnosis of the mixed tumor of the skin, apocrine type. We discuss ten cases that were diagnosed as mixed tumors of the skin at the Department of Dermatology of Kyushu Medical Center and Kyushu University. The papillomatous change in the epidermis of a mixed tumor could be a rare case.View full abstractDownload PDF (1815K) -
Mayuko YAMAKI, Akihiro SAKAKIBARA, Yasusi TOMITA2010 Volume 72 Issue 1 Pages 31-35
Published: February 01, 2010
Released on J-STAGE: May 14, 2010
JOURNAL RESTRICTED ACCESSWe reported three cases of multiple basal cell carcinomas (BCC) with no inducible cause. Case 1, a 76-year-old woman who had 8 small black papules of BCC on the left side of the face. Case 2, a 55-year-old woman had 11 of black papules/macules of BCC on the face, neck, right chest, left lower leg, and left foot. Case 3, a 41-year-old woman had 9 erythematous spots of superficial BCC on the trunk, left arm and right leg. We collected 14 cases of multiple BCC, i.e., 9 cases reported in Japan these 10 years and our 5 cases experienced in our hospital and discussed on their clinical characteristics.View full abstractDownload PDF (1909K) -
Hidemichi KUBO, Kiyohumi EGAWA2010 Volume 72 Issue 1 Pages 36-39
Published: February 01, 2010
Released on J-STAGE: May 14, 2010
JOURNAL RESTRICTED ACCESSWe report a case of actinic keratosis in an 82-year-old woman with a good response to topical indomethacin, one of the non-steroidal anti-inflammatory drugs (NSAIDs). Indomethacin is known as a cox inhibitor that suppresses epithelial tumor cells. In the present case, the efficacy of indomethacin was evaluated not only clinically but also histologically and immunohistochemically using anti Ki-67 antibody. Treatment with topical indomethacin completely cured the lesion within 2 months, not only clinically but also histologically. Within the lesion, the number of Ki-67-positive cells also decreased after the treatment. Topical indomethacin should be a good treatment for actinic keratosis.View full abstractDownload PDF (1487K) -
Koichi TADA, Yuko HIGASHI, Takuro KANEKURA2010 Volume 72 Issue 1 Pages 40-42
Published: February 01, 2010
Released on J-STAGE: May 14, 2010
JOURNAL RESTRICTED ACCESSWe encountered a 28-year-old woman who had an ulcer with induration on her lip that appeared 4 weeks prior to her visit to our department. A biopsy specimen showed inflammatory infiltrates in the entire dermis, mainly composed of plasma cells. Erythematous plaques, 1∼2cm in diameter, without itching, appeared on her trunk and extremities 4 weeks later. A treponemal antigen test and a serological test for syphilis were positive. A diagnosis of syphilis was made based on clinical, histological, and serological findings. She also received a diagnosis of vaginal trichomaniasis. From our detailed interview, she turned out to be a commercial sex worker. Dermatologists should be aware that the primary lesions of syphilis may appear in unusual places because of extravaginal intercourse.View full abstractDownload PDF (1322K) -
Miwa ASHIDA, Ai KURAOKA, Kaori NISHIMURA, Humiyoshi ASHIZUKA, Nobuo US ...2010 Volume 72 Issue 1 Pages 43-47
Published: February 01, 2010
Released on J-STAGE: May 14, 2010
JOURNAL RESTRICTED ACCESSA 15-year-old junior high school student (member of a local sumo club) visited our hospital with scaly erythema on trunk and limbs and black dot ringworm on the left temporal part of the head in March 2007. Trichophyton tonsurans was cultured, and he was healed by hydrochloric acid medication for 3 months. However, since he joined the sumo club of the senior high school, he has suffered from repeated recurrences. At every recurrence, he was medicated with the same drug, and the number of colonies was examined using the hairbrush method. In addition, the number of members of the same club with the same symptoms increased after playing games and expedition training camp. Based on a survey questionnaire, we conclude that lack of appropriate guidance and recognition by the instructor of fungal infections and carriers with no symptoms might lead to repeat recurrence. We suggest that continuous group medical examinations, education of leaders and complete treatment will be necessary to avoid expansion of fungal infections due to interactions of sumo clubs in primary and junior high schools.View full abstractDownload PDF (1477K)
Clinical and Investigative Report
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Takashi SAKAI, Yoshitaka KAI, Seiichi SATO, Mizuki GOTO, Fumiaki SHIMI ...2010 Volume 72 Issue 1 Pages 48-53
Published: February 01, 2010
Released on J-STAGE: May 14, 2010
JOURNAL RESTRICTED ACCESSWe investigated the clinical and pathological features, treatments and prognoses of 18 patients with sebaceous carcinoma who visited the Department of Dermatology at Oita University Hospital from 1984 to 2008. The mean age was 71.8 years (range 36-96 years), and 7 patients were males and 11 were females. Eleven lesions occurred in the eyelid (61.1%), six lesions in the head and neck except eyelid (33.3%), and one lesion in a limb (5.6%). Four patients with ocular sebaceous carcinoma were misdiagnosed as chalazion. None of the patients with extraocular sebaceous carcinoma were diagnosed accurately before biopsy. Five patients in whom histological examinations revealed basaloid cells and necrotic degeneration had lymph node or distant metastasis. Most of the patients were treated by surgery alone or a combination of surgery and other therapies, including chemotherapy and radiation. Three patients received no treatment because of distant metastasis or another concomitant malignancy. Ten patients with no metastasis who underwent surgery had no recurrence in our follow-up periods.View full abstractDownload PDF (1566K)
Review
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Shigetoshi SANO2010 Volume 72 Issue 1 Pages 54-59
Published: February 01, 2010
Released on J-STAGE: May 14, 2010
JOURNAL RESTRICTED ACCESS
Dermatologists around the World
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Masahiro KIRA2010 Volume 72 Issue 1 Pages 81-82
Published: February 01, 2010
Released on J-STAGE: May 14, 2010
JOURNAL RESTRICTED ACCESSDownload PDF (1015K)
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