The Nishinihon Journal of Dermatology
Online ISSN : 1880-4047
Print ISSN : 0386-9784
ISSN-L : 0386-9784
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Volume 48, Issue 3
Displaying 1-23 of 23 articles from this issue
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Clinical Case Reports
  • A Case of Sporotrichosis on the Sole, Which Appeared as a Subcutaneous Induration
    Tatuya KUSABA, Hiroshi KATSUKI, Koichiro MUTO, Tomomichi ONO
    1986 Volume 48 Issue 3 Pages 461-464
    Published: June 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.461
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    A 53-year-old Japanese woman complained of a reddish, slightly elevated, firm 24×32 mm subcutaneous induration on the right sole, of 2 months duration. Biopsy findings revealed a mixed cell granuloma, in which several free and/or intracellular spores were detected, using PAS stain. Sporothrix schenckii was identified from the Sabouraud dextrose agar cultures of tissue taken from the lesion. Sporotrichosis on the sole has never been reported in Japan and mycosis on a palm is extremely rare. The presence of thick, horny and squamous cell layers may act as an important barrier.
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  • A Case of Mixed Tumor of the Parotid Gland
    Hiroyuki TOYOSHIMA, Fumi TORIYAMA, Makoto HORI, Katsutaro NISHIMOTO, H ...
    1986 Volume 48 Issue 3 Pages 465-471
    Published: June 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.465
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    A 56-year-old man had a 3.5 cm painless elastic soft tumor just above the right parotid gland. The mass, loosely fixed with underlying tissue was excised on May 2, 1981. The surgical site healed well, and there was no recurrence 20 months later. Histopathologically, the tumor consisted of epithelial cell nests and myxomatous tissue. Some nests contained ductal structures. No malignant change was observed. An electron microscopic examination revealed numerous fragmented microfilaments and vacuoles in the epithelial cells. There was a basement membrane surrounding the nest. Secretary granules and dense patch, a hallmark of myoepithelial cells were absent. In the myxoid stroma, the cells contained numerous cystic structures. Most of the cells were degenerated and had lost their cytoplasmic membrane. Some of the cystic structure and cytoplasmic organella had ruptured and were exposed to the myxoid stroma. Amorphous mucin-like substances were flowing out into stromal tissue. Thus, it is difficult to confirm that the myoepithelial cell is the origin of mixed tumor of the parotid gland. We assumed that a “blast cell”, which can differentiate to a myoepithelial or to a glandular cell, may be the origin.
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  • A Case of Cutaneous Lupus Erythematosus
    Atsuko YAMAKAMI, Sumiko ICHIKAWA, Yoshiki TANIGUCHI, Masayuki SHIMIZU
    1986 Volume 48 Issue 3 Pages 472-477
    Published: June 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.472
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    A 59-year-old man had edematous erythematous infiltrated skin lesions on the face and also alopecia. A biopsy specimen from the involved skin on the left side of face revealed epidermal atrophy, hydropic degeneration of the epidermal basal layer, dermal edema and mononuclear cell infiltration around dermal blood vessels and appendages. He was classed as a case of 4/11 of SLE, according to criteria of the American Rheumatism Association criteria (1982).
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  • Eight Cases of Porphyria Cutanea Tarda
    Shigeo NONAKA, Taro OHGAMI, Tomio AKIYAMA, Tetsuzo HONDA, Hikotaro YOS ...
    1986 Volume 48 Issue 3 Pages 478-484
    Published: June 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.478
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    Eight men with porphyria cutanea tarda (PCT) ranged in age from 41 to 72 years and had a history of excessive alcohol intake. Distribution of the patients was as follows: six in Nagasaki (one in Nagasaki city, one in Sasebo city, 2 in Higashisonogi county, 2 in Kitamatsuura county), one in Fukuoka, one in Saga. Hyperpigmentation on exposed areas was present in all patients. Small scars, vesicles and erosions were seen in most patients, however, acute photosensitivity was evident only in two. Cutaneous changes were to a lesser degree those than described in previous reports. Urinary porphyrin analysis showed an increase of uroporphyrin (UP) and coproporphyrin (CP) levels and a predominance of UP in 7 of 8 cases. In one, there was an equal excretion of UP and CP in the urine. In the fecal porphyrin analysis, a predominance of CP excretion was seen in six of six patients. The fecal CP/PP ratio was reversed in the patients with PCT, compared to that in normal controls. Slight, abnormalities in liver function were noted in 7 of 8 patients, mainly slight increase of serum GOT, GPT and γ-GTP levels. Liver biopsy was performed in 5 and the histopathology showed evidence of chronic hepatitis. Deposition of iron granules was evident in 4 of 5. Serum iron levels were increased to over 200 μg/dl in 4 of 8. A decrease of unsaturated iron binding capacity was seen in 4 of 8. There was an increase of serum IgG levels over 2,000 mg/dl in 3. From these results, our patients had mild cutaneous changes and slight biochemical abnormalties. It is suggested that cutaneous changes were influenced by the extent sun exposure time, without any correlation between the urinary porphyrin levels and the severity of the cutaneous symptoms.
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Clinical and Investigative Report
  • The Study on Surface Charge of Human Erythrocytes and Neutrophils
    Noriko YOSHIDA
    1986 Volume 48 Issue 3 Pages 485-490
    Published: June 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.485
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    Electrophoretic mobility of erythrocytes and neutrophils was studied in 20 patients with psoriasis vulgaris and bacterial infection and in controls. In result, the negative surface charge of erythrocytes from the patients with psoriasis was much lower than that from controls (p<0.001). That from the patients with bacterial infection was lower than that from controls (p<0.05). The negative surface charge of neutrophils from the patients with psoriasis and bacterial infection was lower than that from controls (p<0.1).
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  • Which Cells are Inducer or Target of Neurofibromas in von Recklinghausen’s Disease?
    Shuhei IMAYAMA, Yutaka YASHIMA, Atsushi IRIKI, Emiko SATO, Harukuni UR ...
    1986 Volume 48 Issue 3 Pages 491-499
    Published: June 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.491
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    Fine structure of neurofibromas developed on the skin of von Recklinghausen’s disease was studied with a special reference to the stroma, using tannic acid and ruthenium red staining. We have demonstrated that the tumor is formed by a complex of “structural constituents”. The element is composed by a central Schwann’s cell-like cell body, coaxially and alternatingly arranged processes of the Schwann-like cell and the fibroblasts, and the connective tissue material between these processes. We found elastica in the stroma, which has never been reported. With increase of the stromal amount, the fibroblast processes became thinner as to embrace the connective tissue but the other processes did not change. The basal lamina (BL) around the Schwann’s cell-like cell processes, which held an axon, frequently extended and mingled with the collagen fibers and the anionic sites on the BL were irregularly distributed. Treatment with chondroitinase ABC resulted no changes on the sites of the BL, but heparinase digested partially the BL itself and reduced the size of the anionic sites on the remaining BL. Coupled with the recent reports that proteoglycans on the BL influence the neighbouring cell proliferation and the stroma formation, our results indicate that the neurofibromas in von Recklinghausen’s disease are originally attributable to the neural component and the proliferated Schwann-like cells and fibroblasts with their product of the connective tissue stroma would be the target and/or morphological results through the neural abnormal induction.
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Review
Statistics
  • Incidence of Dermatophytes in the Dermatological Clinic of Gifu University School of Medicine from 1979 to 1984
    Yukiko SHIKANO, Machiko FUJIHIRO, Manabu MAEDA, Shunji MORI, Haruki SA ...
    1986 Volume 48 Issue 3 Pages 506-512
    Published: June 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.506
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    The incidence and distribution of dermatophytosis in the Dermatological Clinic of Gifu University Hospital from 1979 to 1984 were studied. A total of 1,836 patients with dermatophytosis were studied. The incidence of subjects to all outpatients was 9.9%. There were 17 with tinea capitis, 183 with tinea corporis, 251 with tinea cruris, 967 with tinea pedis, 141 with tinea manus, 270 with tinea unguium, 2 with sycosis parasitaria and 6 with kerion celsi. The majority of the isolated dermatophytes was 787 strains of T. rubrum (77.5%). In addition, 193 strains of T. mentagrophytes (19.0%), 12 of E. floccosum (1.2%), 11 of M. cains (1.1%), 6 of T. violaceum (0.6%), 4 strains of M. gypseum (0.4%), a strain of T. verrucosum (0.1%) and a strain of unidentified dermatophyte were also isolated. The incidences of T. rubrum and T. mentagrophytes were 68.4% and 30.8% in tinea pedis, 87.4% and 9.7% in tinea unguium, 92.3% and 3.6% in tinea cruris, respectively. The ratio of T. rubrum to T. mentagrophytes was 4.1:1.
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