The Nishinihon Journal of Dermatology
Online ISSN : 1880-4047
Print ISSN : 0386-9784
ISSN-L : 0386-9784
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Volume 48, Issue 6
Displaying 1-21 of 21 articles from this issue
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Clinical Case Reports
  • A Case of Pemphigus Vegetans of Hallopeau
    Yoriko SHIMAMOTO, Shuihci INADA, Taizo KOHNO, Noriko KAWASE, Sanae IKE ...
    1986 Volume 48 Issue 6 Pages 1050-1053
    Published: December 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.1050
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    Pemphigus vegetans of Hallopeau occurred in a 45-year-old man, who had oral mucosal lesions and vegetations in the inguinal areas. Some of these vegetations exuded serum and were studded with small pustules. Histopathological examination of the lesions revealed intraepidermal abscesses with many eosinophils. Direct immunofluorescence microscopy indicated deposition of IgG in the intercellular spaces of the epidermis. Indirect immunofluorescence examination of circulating pemphigus antibodies yielded positive results. These findings highly suggest view that pemphigus vegetans of Hallopeau belongs to the pemphigus group.
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  • A Case of Herpetiform Pemphigus-Like Skin Lesions Induced by D-Penicillamine
    Kanichiro NAKAYAMA, Yoshinori SUENAGA, Teruo UENO, Seiichiro AONO
    1986 Volume 48 Issue 6 Pages 1054-1059
    Published: December 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.1054
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    A 41-year-old woman with herpetiform pemphigus-like cutaneous and mucosal lesions was reported. She had a twenty-year history of rheumatoid arthritis and had been controlled with D-penicillamine for the last eleven months. The skin eruptions were anular edematous erythema and erosion with vesicular borders. ANA and anti-ENA antibody were positive. Histopathologically, the epidermis showed a partially moderate spongiosis with some intraepidermal bullae. The single bulla was filled with numerous neutrophils and eosinphils, and slight acantholysis was present at the suprabasal layer. Direct immunofluorescence study showed deposits of IgG in the intercellular spaces of the epidermal cells. With indirect immunofluorescence using frozen sections of normal human skin as the substrate, circulating IgG antibodies against intercellular substance were absent, but such were detected against nuclei of epidermal cells, at a titer of 1:160. D-penicillamine was replaced with oral prednisolone, with good effects.
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  • A Case of Leukomelanoderma Due to Meticrane
    Masahisa WATANABE, Taro OHGAMI, Hiroko IRIFUNE, Kazunori YAMASHITA, Sh ...
    1986 Volume 48 Issue 6 Pages 1060-1064
    Published: December 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.1060
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    A 79-year-old woman with leukomelanoderma due to meticrane was treated. She had been prescribed meticrane for 1.5 years, for hypertension. A leukomelanodermic lesion developed on the sun-exposed areas of her skin, of a one year duration. At the time of admission, no photosensitivity to UVB and UVA was found. After oral administration of meticrane 300 mg/day for 3 days, UVA (2.7∼16.2 J/cm2) was irradiated and an erythemal reaction developed at the areas of 10.8 and 16.2 J/cm2 irradiation. This UVA photosensitivity persisted for 5 weeks. A similar reaction was induced by trichlormethiazide, a drug which she had not been taken. In this case, a photoallergic reaction was suspected because even a small dose of meticrane induced UVA photosensitivity and a cross reaction between meticrane and trichlormethiazide was evident.
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  • A Case of Baker’s Cyst
    Takako YAMAGUCHI, Motoyuki MIHARA, Midori TAKENAKA
    1986 Volume 48 Issue 6 Pages 1065-1067
    Published: December 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.1065
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    A Baker’s cyst developed in the upper medial site in the right knee joint of an overweight 62-year-old woman. The lesion was elastic hard and was located among the deep popliteal muscles and thick subcutaneous fatty tissue. Since it enlarged rather rapidly, a malignant tumor was suspected.
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  • A Case of Wide-Spread Tuberculosis Verrucosa Cutis Suspected to be Chromomycosis
    Kyoko HIRANO, Sumiko NUKADA
    1986 Volume 48 Issue 6 Pages 1068-1071
    Published: December 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.1068
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    We treated a 56 year old man with wide-spread tuberculosis verrucosa cutis. The patient had been on no therapy whatever for about 30 years. Clinically and histologically, a chromomycosis was suspected. Tubercle bacilli from cultures of tissues and dematiaceous fungi from fungal cultures of scales were detected. INAH was prescribed for 3 months and the verrucous plaque improved, however, the blackish pigmentation remained. The dematiaceous fungi was identified to be Alysidium resinae. As it has heretofore never been reported in Japan, the biological characteristics and virulence were also investigated.
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  • Chemical Burn Due to Potassium Silicate Fertilizer
    Kaoru SUZUKI, Yukimasa TAKEDA, Yoshihiro SEI
    1986 Volume 48 Issue 6 Pages 1072-1074
    Published: December 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.1072
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    Potassium silicate fertilizer is a new type of fertilizer which alkalizes soil. We described herein a chemical burn in a 60-year-old woman due to potassium silicate fertilizer. She noted a necrotic lesion over the left ankle after applying fertilizer to her garden for two and half hours. The patch test for two hours produced a necrotic lesion on the back of guinea pigs with fertilizer treated at 41°C for two hours in water. Attention should be drawn to this type of chemical burn as production of fertilizer is on the increase.
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  • A Case of Contact Dermatitis from Amcinonide
    Yohjiro KUBO
    1986 Volume 48 Issue 6 Pages 1075-1078
    Published: December 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.1075
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    A 12-year-old boy was treated with a preparation including Visderm ointment for eczematous dermatitis on the perioral portion. After one month, there was an exacerbation featuring swelling erythema and papulae with itching on the face. Patch tests on the topical preparations used were positive for Visderm ointment, and amcinonide, the principal ingredient of Visderm ointment was positive for each concentration of 1.0, 0.1, 0.05, 0.01 %. The patch test on another 25 topical steroids was negative. Cross reactions among amcinonide and 5 other corticosteroids with similar structures from ketalation on the C16α, C17α cis diaxial bond OH were not confirmed.
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  • Striae Atrophicae Associated with Transudate in the Stroma
    Yoshihiro MAEKAWA, Shinichi ICHIMURA, Wakatoshi MATSUNAGA
    1986 Volume 48 Issue 6 Pages 1079-1081
    Published: December 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.1079
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    A 25-year-old woman with nephrotic syndrome had been on corticosteroids for 8 months. She complained of striae atrophicae associated with transudate in the stroma on the wall of the lower abdomen. It is assumed that this striae are produced by a dysfunction of dermal fibroblasts following oral corticosteroid plus an accumulation of transudate after the breakage of collagen and elastic fibers by mechanical stress.
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Clinical and Investigative Report
  • Analysis of Autoantibodies in Patients with Progressive Systemic Sclerosis
    Reiko NOGAMI, Yoshihiro MAEKAWA
    1986 Volume 48 Issue 6 Pages 1082-1087
    Published: December 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.1082
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    Eleven patients with progressive systemic sclerosis, who were followed from 1976 to 1985 in the Department of Dermatology, Kumamoto University Hospital, were examined regarding clinical features and autoantibodies in the sera. Seven of the eleven had positive anti-Scl-70 antibody. The positive group had other autoantibodies including rheumatoid factor, anti-DNA antibody and anti-ENA antibody, and severe pulmonary fibrosis and progressive exacerbation were present. An anti-centromere antibody positive patient with CREST syndrome did not have anti-Scl-70 and another antibodies.
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  • Surgical Treatment of Eyelid Carcinoma
    —A Review of Data on Nine Surgically Treated Patients—
    Hideki NAKANISHI, Hiroaki NAGAE, Shin HARADA, Katsuyuki TAKEDA
    1986 Volume 48 Issue 6 Pages 1088-1093
    Published: December 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.1088
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    We have surgically treated 9 patients with eyelid carcinoma from 1984∼86. The histopathological diagnosis was basal cell carcinoma in 4 and sebaceous carcinoma in 5. The lower eyelid was affected in 1 and the upper eyelid, medial angle of the eye, lateral angle of the eye and total eyelid were involved in 2 cases each. The manifold tumor locations require different methods of reconstruction. Tumor defects in the region of the medial or lateral angle of the eye were relatively easily covered by local sliding flaps taken from the forehead or the temple. The defect of the lower lid was reconstructed by rotation of the cheek flap. Because of the complex anatomical condition of the upper lid, the deep and large defect required complicated reconstructions. We tried to reconstruct the large defect of upper lid using a lower lid “switch flap”. When the remaining conjunctiva was not sufficient for the inner lining, a composite mucosa-cartilage component from the nasal septum or mucosa from the buccal sulcus were used. There was a local recurrence in 1 with sebaceous carcinoma. The various reconstructive procedures are discussed in detail.
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  • Clinical Studies on Cutaneous Vasculitis
    Part III: Clinical Feature and Course and Prognosis on Periarteritis Nodosa Cutanea (PNC)
    Hitoshi MIYAZAWA, Ichiro KATO, Ryuzo SAITO
    1986 Volume 48 Issue 6 Pages 1094-1100
    Published: December 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.1094
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    We studied the clinical feature and course and prognosis in ten patients whose skin biopsy specimens showed a necrotizing vasculitis and no systemic involvement. Cutaneous manifestations were subcutaneous nodules in ten patients, livedo racemosa in six, ulcers in two, and purpura in one. Extracutaneous manifestations were arthalgias in four, myalgias in three, peripheral neuropathies in four and low grade fever in four, and only the extremities were involved. X-ray examination and electromyograms were normal. Nerve conduction velocity was transiently abnormal in one. All patients had transient inflammatory reactions during the course of the disease. There were no significant immnological abnormalities. The observation period ranged from 5 months to 12 years and 10 months and in no patient was there systemic involvement. It seems that the course can be divided into two groups: a chronic relapsing course and long remission following early active disease. We have no explorations for differences. Fatigue, cold and menstration exacerbates the symptoms.
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