The Nishinihon Journal of Dermatology
Online ISSN : 1880-4047
Print ISSN : 0386-9784
ISSN-L : 0386-9784
Volume 60, Issue 3
Displaying 1-22 of 22 articles from this issue
Color Atlas
Clinical Case Reports
  • Tatsurou TANAKA, Mineko SHIMOHIRA, Noriyuki MISAGO, Yutaka NARISAWA
    1998 Volume 60 Issue 3 Pages 291-294
    Published: June 01, 1998
    Released on J-STAGE: October 15, 2010
    JOURNAL RESTRICTED ACCESS
    We report a 17-year-old female who presented with an aneurysm of the superficial temporal artery. She showed a bean-sized nodule on her left forehead, which was elastic soft with marked pulsation. A minor trauma to the lesion preceded the development. She also had several café-au-lait spots on her face and neck. Moreover, her mother showed similar pigmented lesions which were diagnosed to be neurofibromatosis. The histopathological findings showed a marked thickening of the tunica intima and media due to the proliferation of spindle-shaped cells. Focal myxoid degeneration was observed to be distinctively stained with alcian blue. The proliferating spindle cells within the arterial walls were stained by vimentin and muscle-specific actin, but not by S-100 protein. The relationship between temporal aneurysms and neurofibromatosis is also discussed.
    Download PDF (2239K)
  • Maiko YOKOYAMA, Mitsuharu KAYABA, Tatsurou TANAKA, Noriyuki MISAGO, Yu ...
    1998 Volume 60 Issue 3 Pages 295-298
    Published: June 01, 1998
    Released on J-STAGE: October 15, 2010
    JOURNAL RESTRICTED ACCESS
    We report a case of juvenile dermatomyositis in a 4-year-old boy who presented with Gottron’s sign and violaceous erythema on his face and bilateral knees after sun-exposure. He had no muscular weakness, myalgia nor subcutaneous calcinosis. The serum enzymes were normal. The histopathological findings of his erythematous lesions showed irregular epidermal hyperplasia, the hydropic degeneration of the basal layer, edema of the upper dermis, and perivascular inflammatory infiltration. The immunofluorescence examination of the lesional skin revealed granular deposits of IgA, IgM and C3 at the dermoepidermal junction and papillary dermis. This case was thus diagnosed to be juvenile dermatomyositis, which we carefully observed for 18 months. His skin lesions spontaneously disappeared after 6 months from his first visit, and for 2 years he has lacked muscular weakness and myalgia without any treatment.
    Download PDF (1641K)
  • Takehiko NAKAMURA, Yoshihiro ARAKI, Youichi OZASA, Sunao USHIJIMA, Kei ...
    1998 Volume 60 Issue 3 Pages 299-302
    Published: June 01, 1998
    Released on J-STAGE: October 15, 2010
    JOURNAL RESTRICTED ACCESS
    A 52-year-old female presented at our hospital with erythema on her hands, elbows, knees and dorsal feet with a history of three weeks. Arthralgia, sore throat and low grade fever were also associated, but she had no muscle pain nor weakness. The serum creatine kinase levels were within the normal limits. About two months later, interstitial pneumonitis also developed along with dyspnea and thereafter rapidly progressed. High dose steroid therapy and mechanical ventilation was not effective and she eventually died 14 days after the onset of pulmonary symptoms. A pathological examination at autopsy showed the patient to have had interstitial pneumonitis on both lungs and uterus cancer. Interstitial pneumonitis is a significant complication of dermatomyositis and a life threatening problem. Especially, when rapidly progressive interstitial pneumonitis is complicated, unique clinical symptoms and a poor prognosis are characteristic. New criteria to better elucidate severe type dermatomyositis are needed in order to make an earlier diagnosis.
    Download PDF (2065K)
  • Kayo TAIRA, Reiko MATSUZAKI, Mitsuharu KAYABA, Tatsurou TANAKA, Yutaka ...
    1998 Volume 60 Issue 3 Pages 303-305
    Published: June 01, 1998
    Released on J-STAGE: October 15, 2010
    JOURNAL RESTRICTED ACCESS
    A 28-year-old woman demonstrated edema and multiple red papules on both lower legs with weight loss and an elevated fever after her first child was born in September 1989. The histological findings of epithelioid cell granuloma, negative tuberculin reaction, bilateral hilar lymphadenopathy (BHL), and an incomplete right bundle branch block confirmed the diagnosis of sarcoidosis. The angiotensin converting enzyme level was normal. She was followed up without any medication. Her skin lesions disappeared after her second child was born in June 1994, but thereafter relapsed three months later. This case suggested the existence of a relationship between the cutaneous lesions of sarcoidosis and child birth.
    Download PDF (1112K)
  • Naoki YAMANAKA, Honami NAKAJIMA, Shigeri KAMIYA
    1998 Volume 60 Issue 3 Pages 306-308
    Published: June 01, 1998
    Released on J-STAGE: October 15, 2010
    JOURNAL RESTRICTED ACCESS
    Subcutaneous fat necrosis in a newborn was first reported by Cruse in 1875 and many cases have since been reported worldwide. This disease is clinically characterized by localized subcutaneous indurations, and pathologically by subcutaneous adiponecrosis and panniculitis. Although several theories exist regarding the cause of this disease, many questions remain unsolved. We recently experienced a typical case with this disease. We speculate that various causes may possibly be concerned with this disease. We also reviewed the past cases previously reported and also made a review of the literature regarding this disease.
    Download PDF (1046K)
  • Yumiko KUBOTA, Tetsuya KOGA, Shoji TOSHITANI, Nobuyuki SHIMIZU
    1998 Volume 60 Issue 3 Pages 309-313
    Published: June 01, 1998
    Released on J-STAGE: October 15, 2010
    JOURNAL RESTRICTED ACCESS
    A 7-day-old girl was referred to our department with the chief complaint of generalized erythema with membranous scales. Erosions and bullae were also seen on hands, feet, elbows, knees, buttocks and sacral areas. Because Staphylococcus was detected, she was diagnosed to have staphylococcal scalded skin syndrome. However, the erosions continued to accompany the erythema for more than one year. When she was one year and four months old, she complained of generalized erythroderma and hyperkeratosis in a cobblestone pattern, especially on the intertriginous areas. Histologically, severe hyperkeratosis, acanthosis and a remarkable granular degeneration were observed in the upper portion of the stratum Malpighii. Based on these clinical and histological findings, the diagnosis of bullous congenital ichthyosiform erythroderma was made. She was successfully treated with topical steroid and 20% urea ointments.
    Download PDF (2791K)
  • Tomoe KOTSUJI, Shigeruko IIJIMA, Fujio OTSUKA
    1998 Volume 60 Issue 3 Pages 314-317
    Published: June 01, 1998
    Released on J-STAGE: October 15, 2010
    JOURNAL RESTRICTED ACCESS
    We report the case of a 57-year-old woman with primary biliary cirrhosis (PBC) accompanied with oral lichen planus. In a review of the literature we identified another 13 such cases. All patients including our case were females, ranging from 32 to 80 years old (mean 50.4 years old). Mucous lesions were seen in 13 patients (92.9%). The onset of PBC was earlier than that of lichen planus in eleven patients, seven of which were after treatment with d-penicillamine for PBC. We also discuss the fact that PBC and lichen planus are clinically, histopathologically and immunohistochemically similar to chronic GVHD, in the early lichenoid stage.
    Download PDF (1184K)
  • Makoto ICHIMIYA, Kayo INOUE, Yoshiaki HAMAMOTO, Masahiko MUTO
    1998 Volume 60 Issue 3 Pages 318-320
    Published: June 01, 1998
    Released on J-STAGE: October 15, 2010
    JOURNAL RESTRICTED ACCESS
    We report a case of verrucous skin lesions on the feet which occurred in a case of diabetic neuropathy. A 47-year-old non-insulin-dependent diabetic woman presented with symmetrical verrucous lesions over the first metatarsal heads. A neurological examination showed neuropathy with both sensory and motor loss on the feet and the distal lower legs. Though a histological analysis revealed hyperkeratosis, acanthopapillomatosis, and vacuolated keratinocytes in the epidermal layer mimicking verruca vulgaris, we were not able to detect antigens of human papillomavirus by means of immunohistochemical staining. The etiology of these verrucous lesions might therefore be related to chronic pressure or friction in an area of sensory loss.
    Download PDF (1290K)
  • Masakazu TAKAHARA, Kazunori URABE, Akito TOSHITANI, Shonosuke NAGAE, S ...
    1998 Volume 60 Issue 3 Pages 321-324
    Published: June 01, 1998
    Released on J-STAGE: October 15, 2010
    JOURNAL RESTRICTED ACCESS
    In 1986, a 60-year-old woman presented with an erythematous nodule on her left eyebrow, which had been histologically diagnosed to be a syringoma. Since the lesion had gradually increased in size, the tumor was excised with an ample margin and grafted with a full thickness skin in 1987. The histopathological findings of the lesion appeared to be a morphea-like basal cell epithelioma. Ten years after the excision, the patient again presented with a recurrent tumor next to the grafted skin. We thus performed a wide surgical excision including the previously treated skin. The histopathological findings revealed the characteristic features of the same tumor cells which sometimes formed duct-like structures and horn cysts surrounded with desmoplastic stroma. The cells rarely shawed an nuclear atypia or mitotic figures, yet they invaded into the deep dermis as well as the perineural space. Immunohistochemically, most cells were positive for AE-1/AE-3, partially positive for S-100 protein, and negative for CEA and EMA. These findings thus favored a diagnosis of microcystic adnexal carcinoma which has been recently defined to be a rare, clinically malignant epithelial neoplasm characterized by a histologically benign appearance.
    Download PDF (1820K)
  • Kinuyo KIDA, Junichi KOBAYASHI, Jun TSUJITA, Shinichiro YASUMOTO, Shon ...
    1998 Volume 60 Issue 3 Pages 325-327
    Published: June 01, 1998
    Released on J-STAGE: October 15, 2010
    JOURNAL RESTRICTED ACCESS
    A case of angiosarcoma which developed on the patient’s abdominal wall 7 years after undergoing radiotherapy for carcinoma of the uterine cervix is reported. The patient initially received a local rIL-2 injection and a surgical operation, however, the tumor recurred twice over a period of 3 years. The combined modalities which consisted of a surgical operation, systemic rIL-2 injection, radiotherapy and cryosurgery were all performed successfully. Cryosurgery is thus considered to be effective for ulcerative-nodular lesions of angiosarcoma. The previously reported cases of angiosarcoma occurring on the abdominal wall in Japan were also reviewed.
    Download PDF (1509K)
  • Tomoki OKUDA, Shinji OYAKE, Tsunao OH-I, Michiyuki KOGA
    1998 Volume 60 Issue 3 Pages 328-331
    Published: June 01, 1998
    Released on J-STAGE: October 15, 2010
    JOURNAL RESTRICTED ACCESS
    An asymptomatic subcutaneous induration measuring 2.8×1.5 cm in size appeared in the occipital region of a 47-year-old man in February 1996. On palpation, it seemed to consist of three separate portions. Pathologically, the tumors consisted of basophilic and shadow cells and diagnosed as calcifying epithelioma. The patient had been suffered from myotonic dystrophy since 30 years of age. Recently the relationship between myotonic dystrophy and calcifying epithelioma has attracted much attention. Calcifying epithelioma accompanying myotonic dystrophy is frequently multiple and most often occurs in men, especially in the head as seen in our case. The 70 calcifying epithelioma cases detected in our department over the past 10 years cosisted of only 0.01% of all outpatients and 1.07% of all biopsy specimens. The tumor was more frequent in female, especially in the head, cervix and arm. A solitary occurrence was most frequent and multiple lesions accounted for only 2.85% of all calcifying epithelioma cases in our department.
    Download PDF (1402K)
  • Yuko HIGASHI, Shoko SHIMADA, Yoshihiko KATAHIRA, Mitsuru SETOYAMA, Tam ...
    1998 Volume 60 Issue 3 Pages 332-334
    Published: June 01, 1998
    Released on J-STAGE: October 15, 2010
    JOURNAL RESTRICTED ACCESS
    A 48-year-old woman presented with a soft tissue mass on her back which was associated with pain and tenderness. Microscopically, it was composed of lipomatous, hemangiomatous, myxomatous and leiomyomatous tissue. Twenty-three cases of benign mesenchymorna have been previously reported in Japan and three of them were reported from dermatology.
    Download PDF (1261K)
  • Setsuko MATSUKURA, Takashi MIZUNO, Hiromi OKAZAWA, Hiroki HAYAKAWA, Te ...
    1998 Volume 60 Issue 3 Pages 335-339
    Published: June 01, 1998
    Released on J-STAGE: October 15, 2010
    JOURNAL RESTRICTED ACCESS
    A 91-year-old woman visited our clinic because of a ten-month history of multiple dusky-red colored nodules on her right parietal resion. Raynaud’s phenomenon and sclerosis of the fingers and hands were first noticed at the age of forty. An abnormal shadow was also detected on her chest based on the computed tomography findings. A sample which was excised from the tumor revealed numerous irregular vascular channels and a proliferation of spindle and oval shaped atypical cells in the dermis. Both factor VIII related antigen and CD34 antigen were detected on the endothelial cells of the irregular vascular channels by an immunohistochemical analysis. Therefore, the patient was diagnosed to have a malignant hemangioendothelioma. The patient was also diagnosed to have progressive systemic sclerosis and Sjögren syndrome. She was treated with the intravenous systemic administration of 40×104 JRU of recombinant interleukin-2 once daily. However, the tumor continued to expand. As a result, she eventually died on the 116th hospital day of her admission.
    Download PDF (2613K)
  • Yoshiyuki MURAKAMI, Hiroshi TERAO, Kazunori URABE, Masutaka FURUE
    1998 Volume 60 Issue 3 Pages 340-342
    Published: June 01, 1998
    Released on J-STAGE: October 15, 2010
    JOURNAL RESTRICTED ACCESS
    A case of a spine puncture wound caused by a sea urchin is herein reported. The patient was a 16-year-old male who was injured on both hands at the beach in Hawaii in August 1996. He visited our hospital after coming home, because of awareness of swelling and pain around the wounds, a limited movability of the right 5th finger and lymph node swelling of his right elbow one week after suffering the injuries. He was treated with antibiotics and NSAIDs after the removal of many spines. A reddish nodule appeared on his right palm 2 months after his first visit. The nodule was histologically found to be a foreign body granuloma with a retained spine fragment. The findings of this case are reported while focusing on the diagnostic characteristics not clarified by normal X-rays.
    Download PDF (1096K)
  • Harumi FURUKI, Yoshihiro MAEKAWA, Yoko SHIN, Hitoko SAKAE, Kazutaka TA ...
    1998 Volume 60 Issue 3 Pages 343-345
    Published: June 01, 1998
    Released on J-STAGE: October 15, 2010
    JOURNAL RESTRICTED ACCESS
    A 16-year-old woman, who developed erythematous plaques on both forearms and the right lower leg with a two-year duration was diagnosed to have Crohn’s disease. Only a few such cases have been previously reported in Japan. She developed erythematous plaques following diarrhea, which were quite similar to erythema nodosum. The histological findings obtained from an acute skin lesion revealed non-caseating granulomas with an infiltration of lymphocytes, histiocytes and giant cells in the subcutaneous tissue.
    Download PDF (627K)
Clinical and Investigative Report
  • —Examination of an Utility in Either Side Comparison Test—
    Masahiro HIRAMATSU, Miki SEINO, Akio NAGASE, Satoru ARAI, Hideki MUKAI
    1998 Volume 60 Issue 3 Pages 346-349
    Published: June 01, 1998
    Released on J-STAGE: October 15, 2010
    JOURNAL RESTRICTED ACCESS
    Our experience of salt water therapy for intractable, severe atopic dermatitis suggested an antipruritic effect of this treatment. To confirm the efficacy of salt water therapy, a comparative study was thus performed in patients with bilateral forearm lesions treated with salt water on one side and with pure water on the other side. The extent of itching was evaluated and classified into 10 grades using a visual analogue scale (VAS) method. The itching score was 5.05±1.53 before therapy. After a four-week treatment, it became 2.79±2.35 on the salt water side and 3.90±2.20 on the pure water side. Compared with the value before therapy, the score significantly decreased on both sides. There were also significant differences in the score between the salt water side and pure water side at two and four weeks of therapy. Clinical findings suggested this treatment to be effective for acute eruptions but it also tended to be less useful for more chronic skin lesions. We conclude that salt water therapy has antipruritic and cleaning effects and it is therefore worth attempting in the treatment of acute eruptions as an ancillary therapy for refractory itching.
    Download PDF (1247K)
Review
Therapy
Dermatologists around the World
feedback
Top