The Nishinihon Journal of Dermatology
Online ISSN : 1880-4047
Print ISSN : 0386-9784
ISSN-L : 0386-9784
Search
Advanced search
OR
Browse
Search
Volume 69, Issue 5
Displaying 1-16 of 16 articles from this issue
Show all abstracts
    • |<
    • <
    • 1
    • >
    • >|
Color Atlas
Mini Review
Clinical Case Reports
  • Successful Treatment of Palmoplantar Pustulosis Associated with IgA Nephropathy and Osteoarthropathy with Tonsillectomy
    Rieko KURAHASHI, Tadashi ISHIKAWA, Yutaka HATANO, Kazumoto KATAGIRI, S ...
    2007 Volume 69 Issue 5 Pages 492-495
    Published: October 01, 2007
    Released on J-STAGE: November 06, 2007
    DOIhttps://doi.org/10.2336/nishinihonhifu.69.492
    JOURNAL RESTRICTED ACCESS
    Show abstractHide abstract
    A 53-year-old Japanese man presented with eruptions on his palms and soles of a duration of 2 years. We had diagnosed palmoplantar pustulosis (PPP), which was associated with chronic tonsillitis, osteoarthropathy and IgA nephropathy. The skin lesions, symptoms of osteoarthropathy and accumulations on bone scintigraphy improved after tonsillectomy, although the proteinuria persisted. We should keep in mind tonsillectomy as one method to control PPP, which is accompanied by intractable skin lesions and painful oeteoarthropathy.
    View full abstract
    Download PDF (673K)
  • A Case of Sweet's Syndrome Associated with Sjögren's Syndrome
    Satoko KUMAZAWA, Shonosuke NAGAE, Sachiko HARA, Yoshiteru UEDA
    2007 Volume 69 Issue 5 Pages 496-500
    Published: October 01, 2007
    Released on J-STAGE: November 06, 2007
    DOIhttps://doi.org/10.2336/nishinihonhifu.69.496
    JOURNAL RESTRICTED ACCESS
    Show abstractHide abstract
    We report a 33-year-old female who presented to our hospital in 2001 with tender erythemas on the face and extremities, which involved pustules and vesicles. She then developed a sore throat and high fever. Results of blood tests showed polymorphonuclear leukocytosis and elevated CRP and ESR. Histopathological findings were consistent with Sweet's syndrome based on diffuse infiltration of predominant neutrophils with nuclear dust. Administration of oral predonisolon immediately reduced all of her symptoms. In 1998, she had been diagnosed with Sjögren's syndrome. She has had recurrent acute attacks similar to that described here for 7 years since the first diagnosis. We reviewed reported cases of Sweet's syndrome associated with Sjögren's syndrome.
    View full abstract
    Download PDF (995K)
  • Drug Eruption Induced by Imatinib Mesylate (Glivec®)
    Yuji INOUE, Hironobu IHN, Takashi GYOTOKU, Isamu IKEDA
    2007 Volume 69 Issue 5 Pages 501-504
    Published: October 01, 2007
    Released on J-STAGE: November 06, 2007
    DOIhttps://doi.org/10.2336/nishinihonhifu.69.501
    JOURNAL RESTRICTED ACCESS
    Show abstractHide abstract
    We report a 58-year-old woman with drug eruptions induced by the BCR-ABL tyrosine kinase inhibitor, Glivec®. One month after the beginning of administration of Glivec® (400 mg/day), multiple areas of erythema over the entire body with itching erupted. We obtained a biopsy specimen of the erythema and made the diagnosis of erythema exudative multiforme. We treated the patient with corticosteroid administration (betamethasone 0.5 mg/day) and reduced the dosage of Glivec® (200 mg/day). One month later, the erythema reappeared and hyperkeratosis with scales on the palms and soles appeared. Purpura on both legs followed in two months. DLST for Glivec® was negative. We also reported 4 other cases with drug eruptions induced by Glivec®.
    View full abstract
    Download PDF (909K)
  • Polyarteritis Nodosa Cutanea with a Varied Course
    Yumiko KUBOTA, Kaori KOGA, Juichiro NAKAYAMA
    2007 Volume 69 Issue 5 Pages 505-510
    Published: October 01, 2007
    Released on J-STAGE: November 06, 2007
    DOIhttps://doi.org/10.2336/nishinihonhifu.69.505
    JOURNAL RESTRICTED ACCESS
    Show abstractHide abstract
    A 17-year-old nursing student presented with dark purpuric macules on the bilateral lower legs in April, 2005 and petechiae of the feet in June. A biopsy specimen of petechia of the foot revealed thrombus in vessels and infiltrates of lymphocytes around the vessels in the entire dermis. Serum dilution of anti-nuclear antibody was 1:80, but there were no antineutrophil cytoplasmic autoantibodies, lupus anticoagulant and anti-cardiolipin antibodies. We diagnosed this case as livedoid vasculopathy. The patient thereafter developed purpura and swelling of the bilateral lower legs and feet with neuropathy. Second biopsy specimens of purpura of the right foot revealed necrotizing vasculitis in all of the vessels of the dermis into the subcutaneous fat. After a diagnosis of vasculitis allergica cutis (Ruiter) and polyarteritis nodosa cutanea (PNC) was made, oral steroid was administered with good response. With tapering of steroid, some subcutaneous nodules appeared. Histopathological examination revealed necrotizing vasculitis in the arterioles of subcutaneous fat, and again a diagnosis of PNC was made. Good results were obtained from oral steroid therapy for another 2 months. We had some difficulties in making a definite diagnosis. We finally diagnosed this case as PNC because of livedo-like eruption of her legs, necrotizing vasculitis of arterioles in the subcutaneous fat and no systemic symptoms. The necrotizing vasculitis of all of the vessels in the dermis mimicking Ruiter was thought to have been a secondary change caused by PNC. Long-term follow-up of this case is essential.
    View full abstract
    Download PDF (2185K)
  • Lentigo Maligna Partially Treated with Ruby Laser
    Takako KURIHARA, Yoshihide HONDA
    2007 Volume 69 Issue 5 Pages 511-514
    Published: October 01, 2007
    Released on J-STAGE: November 06, 2007
    DOIhttps://doi.org/10.2336/nishinihonhifu.69.511
    JOURNAL RESTRICTED ACCESS
    Show abstractHide abstract
    A 73-year-old woman had had a black-brown macule on the left cheek for the previous 20 years. Recently, the black spots in the center of the lesion had been treated with ruby laser. A few days after that treatment, she came to our hospital because the treated area had eroded. After epithelialization, the lesion was an irregular, relatively well-defined, dark or light black-brown macule 28×11 mm in diameter, with black and white spots in the center, presumably as a result of the previous laser treatment. Based on clinical features and histopathologic findings, we made a diagnosis of lentigo maligna. The lesion was surgically excised, and, additionally, local injection of interferon-β was administered. There has been no recurrence in 27 months. Histologically there were only rare nested atypical melanocytes, but many single melanocytes in the area that been recently treated. Our experience suggests that ruby laser treatment of lentigo maligna may not be curative.
    View full abstract
    Download PDF (860K)
  • A Case of Adult T-cell Leukemia/Lymphoma (ATLL) with Specific Features of Panniculitis-like Lesions
    Mami KOMESU, Yu-ichi YAMAMOTO, Yutaka ASATO, Makiko GUSHI, Yumie GIBO, ...
    2007 Volume 69 Issue 5 Pages 515-520
    Published: October 01, 2007
    Released on J-STAGE: November 06, 2007
    DOIhttps://doi.org/10.2336/nishinihonhifu.69.515
    JOURNAL RESTRICTED ACCESS
    Show abstractHide abstract
    A case of ATLL in an 81-year-old woman is reported. She noticed redness and swelling on the right thigh and diffuse erythema on the entire body around August 2000. She was hospitalized in December 2000 with such findings as redness and swelling on the right thigh with local heat and tenderness, pitting edema on the right leg, and inguinal regional lymph node swelling. Laboratory findings included positive reactivity to HTLV-1 antibody and higher titer of soluble IL-2 receptor. Histopathological examination revealed dense infiltration of numerous neoplastic lymphocytes with conspicuous atypia and mitosis from the dermis to the subcutaneous fatty tissue, suggesting a diagnosis of ATLL. Monoclonal integration of HTLV-1 proviral DNA and existence of defective types of HTLV-1 proviruses in the affected tissues were observed in a sample of a subcutaneous lesion by Southern blot technique. Those results confirmed the diagnosis of ATLL with panniculitis-like lesions. Cases of T cell lymphoma with panniculitis-like lesions are well known, but those of ATLL are rare. Review of the literature revealed only four such cases, including our case, in Japan. In two, EB-virus encoded small RNA (EBER) was found in the tumor cells. However, in the present case, EBER was negative by the in situ hybridization method using skin lesion and regional lymph-node tissues. We reported here a case of ATLL with panniculitis-like lesions in which EB viruses were not involved. The clinical symptoms were resistant to various therapies. Her course was poor with a short survival period of 14 months after hospitalization.
    View full abstract
    Download PDF (1079K)
  • Long-term Survival in a Patient with Adult T-cell Leukemia/Lymphoma (ATLL):
    A Case Report
    Yoshiko MINE, Yu-ichi YAMAMOTO, Kiyohito TAIRA, Ryoko AWAZAWA, Yutaka ...
    2007 Volume 69 Issue 5 Pages 521-526
    Published: October 01, 2007
    Released on J-STAGE: November 06, 2007
    DOIhttps://doi.org/10.2336/nishinihonhifu.69.521
    JOURNAL RESTRICTED ACCESS
    Show abstractHide abstract
    An 83-year-old male had red papules with itching since he was 53 years old. He had received lotions and other topical agents for an allergic disease from a physician, but the symptoms gradually expanded. In February 1989 (68-years-old), he visited our hospital because of papules on his body as well as nodules on both cheeks, which had appeared in September 1988. The diagnosis based on biopsy was malignant lymphoma. The following year we confirmed the diagnosis of adult T-cell leukemia/lymphoma (ATLL) with Southern blot technique from a skin sample from the nodule on the left cheek. He was given topical corticosteroids, intramuscular injections of interferon-alpha, treatment by PUVA, electron beam, and soft X-ray beam as well as other therapies. His condition has alternatively both worsened and improved over this period. However, after 15 years he is still alive. ATLL is considered to be a severe, malignant type of lymphoma, but in Japan there have been reports of long-term survivors, such as our case. We in the Dermatology Clinic in the University of Ryukyu Hospital have had 16 cases of the type of ATLL manifested by nodules/tumors over the past 15 years. The survival period for these 16 patients has ranged from 5 months to 15 years, with a mean survival duration of 24.3 months. Only 2 of the 16 patients survived more than 5 years, including the present case. In 2004, another red nodule appeared on this patient's left arm. He accepted soft X-ray beam treatment and improvement has been noted.
    View full abstract
    Download PDF (2316K)
  • A Case of Low Grade Porocarcinoma
    Yuta KURASHIGE, Yukari OKUBO, Hinako UCHIDA, Ryoji TSUBOI, Miki IZUMI
    2007 Volume 69 Issue 5 Pages 527-530
    Published: October 01, 2007
    Released on J-STAGE: November 06, 2007
    DOIhttps://doi.org/10.2336/nishinihonhifu.69.527
    JOURNAL RESTRICTED ACCESS
    Show abstractHide abstract
    A 64 year-old-male with a red tumor on his head, visited our hospital. The patient had suffered injury to his head at the age of 15. When he was 20 years old, he noticed a small nodule on his head, coinciding with the site of the injury, which was then resected. Subsequently, the nodule reappeared and has been increasing gradually in size from the age of 40. The clinical appearance consisted of a pediculated red tumor, 46×48×11mm in size, showing signs of erosion on the surface in his parietal field. The tumor was excised subsequent to the biopsy. Pathologically, the tumor nests consisted of small, uniform, cuboidal poroid cells with differentiation to the sweat duct were proliferated. Although the border with the normal tissue was relatively clear, in deeper areas the tumor nest, characterized by slight nuclear atypia, had infiltrated into the dermis. This tumor was diagnosed as a “low grade porocacinoma.”
    View full abstract
    Download PDF (1717K)
Review
Statistics
  • Clinical Study of 21 Cases of Snakebite by Mamushi, a Japanese Pit Viper during the Past 2 Years
    Atsuto UEDA, Satoshi MIKURIYA, Shinichiro YASUMOTO, Takashi HASHIMOTO
    2007 Volume 69 Issue 5 Pages 542-546
    Published: October 01, 2007
    Released on J-STAGE: November 06, 2007
    DOIhttps://doi.org/10.2336/nishinihonhifu.69.542
    JOURNAL RESTRICTED ACCESS
    Show abstractHide abstract
    We experienced a total of 21cases of snakebite by mamushi, a Japanese pit viper, from April 2003 to March 2005 at our hospital and studied the clinical features in these patients. Results showed that the most prevalent season for such bites was between August and September. Most of the patients were in their sixties and were admitted to the emergency room of our hospital from 12 : 00 to 20 : 00. The most affected sites of the body were the fingers followed by the toes. The accidents tended to be more frequent on cloudy days. Hospitalization period was longer for patients with severe symptoms. All of these patients were treated with therapy that included local incision, cepharanthin and antivenin. Because the serum sickness that might occur after administration of antivenin was reported in the literature to be not significant, antivenin treatment should be recommended to rapidly ease the symptoms of this snakebite.
    View full abstract
    Download PDF (356K)
Therapy
  • Efficacy of Luliconazole 1% Cream (Lulicon® Cream 1%) for Tinea Pedis
    Takahiro YAMAGUCHI, Monji KOGA, Yumiko ARAO, Ryota TOKUMARU, Akira TAK ...
    2007 Volume 69 Issue 5 Pages 547-553
    Published: October 01, 2007
    Released on J-STAGE: November 06, 2007
    DOIhttps://doi.org/10.2336/nishinihonhifu.69.547
    JOURNAL RESTRICTED ACCESS
    Show abstractHide abstract
    We investigated the efficacy, safety, and usefulness of once-daily application of luliconazole 1% cream (Lulicon® cream 1%) for the treatment of tinea pedis at the Department of Dermatology School of Medicine Fukuoka University Hospital and its affiliated centers. Forty-three patients (25 with interdigital and 18 with vesicular) were included in the analysis. After application of Lulicon® for 4 weeks, rates of improvement in dermatological symptoms were 93.8% and 100% and of mycological efficacy (fungi-negative rate) were 100% and 58.3% for interdigital and vesicular tinea pedis, respectively. The efficacy rates in the overall evaluation, which included assessment of dermatological symptoms and results of mycological testing, were 100% and 58.3% for interdigital and vesicular tinea pedis, respectively. Itching disappeared in 58.8% of all patients within one week. Based on these results, and the absence of adverse drug reactions, luliconazole 1% cream (Lulicon® cream 1%) is considered to be quite effective and useful for the treatment of tinea pedis.
    View full abstract
    Download PDF (428K)
  • Effects of Bepotastine Besilate on Clinical Usefulness with Chronic Urticaria Based on Patient-centered Evaluation and Patients' QOL
    Yasuo KUBOTA, Tetsuya MORIUE, Kozo NAKAI, Yoshie MATSUOKA, Ikumi YOKOI ...
    2007 Volume 69 Issue 5 Pages 554-560
    Published: October 01, 2007
    Released on J-STAGE: November 06, 2007
    DOIhttps://doi.org/10.2336/nishinihonhifu.69.554
    JOURNAL RESTRICTED ACCESS
    Show abstractHide abstract
    Bepotastine besilate is a second generation anti-histamine drug, and its excellent efficacy and high safety on a variety of allergic diseases have been reported. In this study, bepotastine besilate was administered to patients with chronic urticaria, and we investigated both patient-centered clinical efficacy and improvement of QOL based on evaluation sheets written by patients. Total 20 patients were evaluated. As a result, bepotastine besilate administered twice daily is effective and well tolerated in the treatment of the symptoms of chronic urticaria and in improving the patients' QOL. Significant improvements were observed in all clinical score items (pruritus in the daytime, pruritus at night, the distribution of weals, the number of daily urticarial episodes, the duration time of weals, the severity of weals) evaluated by patients at the second visit (1-2 weeks after) compared with those at the base line, and effects of bepotastine besilate continued until the end of treatment. “Total” score and all subscale scores except “Personal Relationships.” in DLQI (Dermatology Life Quality Index), which is a skin disease-specific QOL evaluation, were significantly improved. In case of WHO QOL 26, which is a comprehensive QOL evaluation, average score of a total of 26 items was 3.44 before the treatment. This score was almost the same with 3.29 of healthy Japanese. After the treatment of bepotastine besilate, a significant improvement was observed in “overall” which is one of subscale in WHO QOL 26. These results suggested that the treatment with bepotastine besilate 10mg twice daily is an effective agent in patients with chronic urticaria, as its action provides a rapid and satisfactory improvement of the clinical symptoms and the patients' QOL.
    View full abstract
    Download PDF (514K)
Dermatologists around the World
    • |<
    • <
    • 1
    • >
    • >|
feedback
 Top