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Volume 70 (2008)
- Issue 6 Pages 595-
- Issue 5 Pages 473-
- Issue 4 Pages 369-
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- Issue 2 Pages 129-
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Volume 70, Issue 6
Displaying 1-14 of 14 articles from this issue
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Color Atlas
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Ayako ONOUE, Yoshiki TOKURA, Hiroshi YASUDA, Osamu YAMAMOTO2008 Volume 70 Issue 6 Pages 595-596
Published: December 01, 2008
Released on J-STAGE: January 20, 2009
JOURNAL RESTRICTED ACCESSDownload PDF (839K)
Clinical Case Reports
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Aiko TAKEUCHI, Shigeru SUGANO2008 Volume 70 Issue 6 Pages 597-600
Published: December 01, 2008
Released on J-STAGE: January 20, 2009
JOURNAL RESTRICTED ACCESSA 69-year-old woman noticed a painful red nodule on the bottom of her right helicis. After 8 months, a bean-sized red nodule with crust in her right helicis became apparent. Surgical resection was performed 3 times for the same lesion. Pathological findings of the specimen were non-specific. The lesion quickly relapsed. Finally, histopathological examination from the 4 th resection showed vascularized granulation and fibrinoid degeneration of collagen with inflammatory cell infiltration. We made the diagnosis of chondrodermatitis nodularis chronica helices. She slept on her right side, which might have caused prolonged and excessive pressure on the affected side. We here provide information on the treatment of chondrodermatitis chronica nodularis helicis from previous reports.View full abstractDownload PDF (859K) -
Yoshiko MINE, Yu-ichi YAMAMOTO, Yutaka ASATO, Kiyohito TAIRA, Shigetak ...2008 Volume 70 Issue 6 Pages 601-605
Published: December 01, 2008
Released on J-STAGE: January 20, 2009
JOURNAL RESTRICTED ACCESSA 67-year-old woman visited a local orthopedist in February 2007 because of edema of the fingers. She was administered predonisolone at a dosage of 5 mg/day. As the symptoms did not improve, bucillamine was added. Because of high fever, general fatigue, facial edema, eruptions over the entire body and oral pain that developed in March 2007, she presented at our hospital. Histological examination of the fingers revealed growth and swelling of collagen fibers. Anti-nuclear antibody, rheumatoid factor, anti-U1 ribonucleoprotein antibody, anti-SS-A/Ro antibody, and anti-cyclic citrullinated peptide antibody were all positive and the titer was high for matrix metalloproteinase-3. Chest computed tomography revealed interstitial hypertrophy and ground-glass appearance. From the above findings, we diagnosed the present illness as limited cutaneous systemic sclerosis, rheumatoid arthritis, and Sjögren's syndrome. Oral administration of predonisolone 30 mg/day improved the symptoms. Since the patient was a carrier of HTLV-1, we discussed HTLV-1 and collagen disease.View full abstractDownload PDF (903K) -
Shihoko OKAZAKI, Fumihide OGAWA, Toshifumi YAMAOKA, Shinichi SATO, Ken ...2008 Volume 70 Issue 6 Pages 606-609
Published: December 01, 2008
Released on J-STAGE: January 20, 2009
JOURNAL RESTRICTED ACCESSWe report a 49-year old female patient who had dermatomyositis with mechanic's hand. She had erythema on her face and hands 1 month before visiting our hospital. She visited our hospital in February, 2006 and dermatomyositis was diagnosed according to the presence of heliotrope rashes, Gottron's signs, and characteristic erythema with hyperkeratosis (mechanic's hand). Chest computed tomography revealed interstitial pneumonia. Serum creatine phosphokinase levels were within the normal range. Therefore, the patient was given a diagnosis of amyopatic dermatomyositis. Furthermore, we suspected the diagnosis of antisynthetase syndrome by the presence of mechanic's hand and interstitial pneumonia. Daily oral prednisolone of 40 mg in combination with cyclosporine of 125 mg were administered for active interstitial pneumonia. The skin and lung involvement was gradually improved. Immunoprecipitation assay revealed that she had no antisynthetase autoantibody. Thus, it is suggested that the existence of mechanic's hand, which is highly associated with antisynthetase syndrome, dose not always lead to the diagnosis of antisyntetase syndrome.View full abstractDownload PDF (906K) -
Yukari YOSHIDA, Keiko OMURA, Yoshinao MURO, Yasushi TOMITA2008 Volume 70 Issue 6 Pages 610-613
Published: December 01, 2008
Released on J-STAGE: January 20, 2009
JOURNAL RESTRICTED ACCESSWe report a patient with systemic sclerosis who had severe complications involving the internal organs that were difficult to control. The patient was a 55-year-old male who had developed interstitial lung disease in 2002. The following year, he noticed edematous thickening of the fingers and myositis. Both respiratory and skin symptoms were improved after 6 courses of cyclophosphamide pulse treatment. Beginning in 2006, pneumothorax frequently occurred followed by dyspnea, which gradually became exacerbated; thus, home oxygen therapy was prescribed. In November 2006, myositis relapsed which was partially improved by steroid pulse therapy and immunoglobulin administration. After that, various complications developed, one after another, i.e., gastroesophageal reflux syndrome, paroxysmal supraventricular tachycardia, and pseudoobstruction of the intestine; the latter was somewhat improved by erythromycin. Finally, hyperalimentation through a central venous catheter from laceration of the subclavian vein was performed in place of the erythromycin administration, since liver dysfunction was probably due to the antibiotic. His condition improved and he continued home parenteral hyperalimentation after leaving the hospital.View full abstractDownload PDF (1004K) -
Yutaka KUWATSUKA, Kazuhiro KOMURA, Yuichirou AKIYAMA, Fumihide OGAWA, ...2008 Volume 70 Issue 6 Pages 614-617
Published: December 01, 2008
Released on J-STAGE: January 20, 2009
JOURNAL RESTRICTED ACCESSA 11-year-old boy had recognized symmetrical diffuse skin sclerosis and swelling of his distal extremities for 1 year. Contractures of his phalanges, carpal joints, and ankle joints were appeared 7 months before his visiting our department. Skin sclerosis of his fingers and toes was not observed. In addition, there were no signs of Raynaud's phenomenon and nailfold bleedings. Laboratory findings revealed that slight eosinophilia and hypergammaglobulinemia. Antinuclear antibody, anti-topoisomerase-I antibody, and anti-centromere antibody were negative. Deep fascial biopsy from the forearm showed thickened fascia and moderate inflammatory infiltration without eosinophils. Accordingly, he was diagnosed as eosinophilic fasciitis. Although the skin sclerosis and swelling of extremities rapidly disappeared after daily oral administration of 25 mg prednisolone, contracture of his fingers and his carpal and ankle joints persisted. The rehabilitation program gradually improved these contractures. It seems to be necessary to keep in mind the diagnosis of eosinophilic fasciitis even though it is rare in children.View full abstractDownload PDF (988K) -
Eri MORIYAMA, Sayaka SHIBUI, Ken IMAI, Yohei OKADA, Shigeyoshi KAMATA2008 Volume 70 Issue 6 Pages 618-620
Published: December 01, 2008
Released on J-STAGE: January 20, 2009
JOURNAL RESTRICTED ACCESSWe report a case of skin metastasis from prostatic cancer in a 66-year-old male. The patient had a red tumor 30×25 mm in diameter on the region of the left chest. Histology revealed the tumor to be an adenocarcinoma, and immunohistochemistry showed the tumor to be prostate-specific antigen positive. Examination of a biopsy specimen of the prostate revealed adenocarcinoma, and the patient was diagnosed as having prostatic cancer with metastases to the skin and mediastinal lymph nodes. He was administered antiandrogenic hormonal agents. Thirteen cases of skin metastasis from prostatic cancer diagnosed from skin metastasis have been reported in Japan, including our report.View full abstractDownload PDF (888K) -
Yoshio ITO, Tetsuo SASAKI, Yoshiko YATA, Junko KAWASHIMA, Shinichi TAK ...2008 Volume 70 Issue 6 Pages 621-624
Published: December 01, 2008
Released on J-STAGE: January 20, 2009
JOURNAL RESTRICTED ACCESSA 12-year-old girl with Down syndrome presented with small whitish papules on the dorsum of her hands and feet and syringoma-like structures on the inferior eyelids and cheeks. Histopathological examination of a hand lesion revealed subepidermal calcium deposits with thinned epidermis and foreign body reaction at the bottom of the nodule. Thus, this case was diagnosed as Down syndrome with multiple milia-like calcinosis on the extremities and syringomas.View full abstractDownload PDF (923K) -
Hajime TOMITA, Youhei IWATA, Humihide OGAWA, Shinichi SATO, Yuuichirou ...2008 Volume 70 Issue 6 Pages 625-629
Published: December 01, 2008
Released on J-STAGE: January 20, 2009
JOURNAL RESTRICTED ACCESSWe report a 50-year-old female patient of malignant melanoma (MM) on the right sole arising from a lesion of palmoplantar keratoderma. The keratotic lesion appeared on her palm and sole at birth. She was treated with topical ointment, and shave resection of the keratotic lesion was performed many times. The melanotic macule on the right sole had appeared two years before her visiting our hospital. Because of the spreading pigmented macule and developing erosive nodule, she visited our hospital in August, 2008. The clinical findings revealed malignant melanoma with palmoplantar keratoderma. The tumor resection was performed with 2 cm margin. After treatment of etretinate for the keratoderma, the remaining pigmented macule appeared. Additional operation for removal of the remaining tumor was performed. It is suggested that malignant melanoma with palmoplantar keratoderma should be treated carefully before operation for the accurate resection margin.View full abstractDownload PDF (902K) -
—with Results of Mycological Examination for T. glabrum Performed at the Nursing Home—Hidekazu SHINODA, Hanako SEKIYAMA, Katsutaro NISHIMOTO2008 Volume 70 Issue 6 Pages 630-633
Published: December 01, 2008
Released on J-STAGE: January 20, 2009
JOURNAL RESTRICTED ACCESSThe proband was a 44-year-old female certified nursing aide who presented with marginally elevated squamous erythema on the dorsal side of the right upper arm. We isolated Trichophyton glabrum (T. glabrum) from the lesion and assigned the diagnosis of tinea corporis. Subsequently, we examined the staffand residents of the nursing home for T. glabrum using the hairbrush (HB; 90 bristles) method. Thirty-nine employees and 92 residents were examined. None of the employees had a tinea lesion and their HB samples were negative. T. glabrum was identified in 14 HB-positive samples from the residents. Examination of the head of these patients revealed that 2 cases had black dot ringworm, 4 had a pityriasis-like rash, and 8 were asymptomatic carriers. The degree of disability in these patients was severe according to classification of the Ministry of Health, Labour and Welfare, meaning that they either could not leave their bed or stand alone and were totally dependent on help from nursing aides. Therefore, we inferred that the fungus was transmitted from the head of a resident to the arm of the aide. We were not able to identify the source among the residents, but concluded that the usage of hairbrushes during bathing of residents must be the reason for the outbreak of HB-positive cases.View full abstractDownload PDF (932K)
Clinical and Investigative Report
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Yuuka SHIBATA, Hiroaki IKEDA, Kenji KIHIRA2008 Volume 70 Issue 6 Pages 634-638
Published: December 01, 2008
Released on J-STAGE: January 20, 2009
JOURNAL RESTRICTED ACCESSTo clarify the physical properties of ethical urea ointments administered to the skin, we conducted a questionnaire survey using the sensory test method for eight preparations. Subjects were 110 healthy volunteers who worked in Hiroshima University hospitals. Spreadability, odor, viscosity (sticky and oily), whitening after application of ointments as properties that would affect QOL and comfort were compared among test preparations as well as standard preparations. 10% and 20% Acetylol® ointments ranked highly in comfort level, ease of spreadability, faint odor and low viscosity. Results showed that Acetylol® brands ranked highly in comfort level among the tested urea topical ointments. Moreover, the comfort level correlated well with spreadability, viscosity and whitening after ointments were applied. This type of information is useful for dermatologists and pharmacists in improving compliance and choosing a urea topical ointment.View full abstractDownload PDF (1022K) -
— a Pressure Ulcer Evaluation Scale — at Fukuoka University HospitalShinichi IMAFUKU, Juichiro NAKAYAMA, Taro MAKINO, Masaaki KOSAKA, Akik ...2008 Volume 70 Issue 6 Pages 639-644
Published: December 01, 2008
Released on J-STAGE: January 20, 2009
JOURNAL RESTRICTED ACCESSPressure ulcers are important conditions associated with all branches of medicine. The DESIGN system as a tool to evaluate pressure ulcers and the degree of penetration among nurses at our university hospital was assessed by a questionnaire. Among 584 questionnaires collected (collection ratio, 94%), 79% of the nurses were aware of the DESIGN system, and 35% had experience in using this tool. The recognition ratio was in proportion to the length of the careers of the nurses. Working experience in departments that are more responsible than other units for frail elderly patients (heart disease unit, neurology unit), more seriously ill or injured patients (emergency room, operation room) and dermatology/plastic surgery units did not show significant difference. In considering individual items, 88% of responders answered that they occasionally felt it was difficult to judge items D (depth) and I (inflammatory/infection), 84% for G (granulation tissue), 78% for P (pocket), and 75% for N (necrotic tissue). These data can be used as the basis for effective education programs, and, if necessary, for revising the DESIGN system itself.View full abstractDownload PDF (1730K)
Review
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—Cancer Chemoprevention Targeting COX-2—Takuro KANEKURA2008 Volume 70 Issue 6 Pages 645-650
Published: December 01, 2008
Released on J-STAGE: January 20, 2009
JOURNAL RESTRICTED ACCESSDownload PDF (1187K)
Dermatologists around the World
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Mitsuru SETOYAMA2008 Volume 70 Issue 6 Pages 655-656
Published: December 01, 2008
Released on J-STAGE: January 20, 2009
JOURNAL RESTRICTED ACCESSDownload PDF (883K)
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