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Volume 42 (1967)
- Issue 6 Pages 367-
- Issue 5 Pages 291-
- Issue 4 Pages 217-
- Issue 3 Pages 151-
- Issue 2 Pages 83-
- Issue 1 Pages 1-
Volume 42, Issue 6
Displaying 1-4 of 4 articles from this issue
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SAMUEL H. HORI, TSUTOMU KAMADA1967 Volume 42 Issue 6 Pages 367-374
Published: 1967
Released on J-STAGE: May 21, 2007
JOURNAL FREE ACCESSGlucose 6-phosphate dehydrogenases extracted from various organs of mice, rats, hamsters and guinea pigs, and from human red blood cells were separated into several molecular forms by means of acrylamide disc electrophoresis.
Two major forms of G6PD were demonstrated in each animal which differed not only in electrophoretic mobility, but also in intracellular location and reactivity to inhibitors; one moved slowly, located mainly in microsomal fraction and was resistant to inhibitors, while the other moved rapidly, located in mitochondria and cell sap, and was sensitive to inhibitors. The latter form of G6PD appeared to be homologous to the sex-linked G6PD of human red cells.
Isoenzyme pattern showed sex difference in the liver of rats and in the plasma of mice. In the rat liver, band D enzyme was more active in females than in males, while in mouse plasma, band I enzyme was more active in males than in females. Both bands exhibited the same electrophoretic mobility.View full abstractDownload PDF (1802K) -
TAKAO K. WATANABE1967 Volume 42 Issue 6 Pages 375-386
Published: 1967
Released on J-STAGE: May 21, 2007
JOURNAL FREE ACCESS1. Segregation distorter genes (SD) were found in Kofu and Katsunuma natural populations of Drosophila melanogaster.
2. The nature of SD gene extracted from Kofu and Katsunuma populations was almost the same as in Madison; segregation distortion occurred only in SD heterozygous males and it did not occur either in SD homozygous males or in females.
3. SD gene was mostly found in association with a right arm inversion, In(2R)C, and some SD chromosomes simultaneously carried the same persistent lethal gene which was frequently found and maintained in Kofu and Katsunuma natural populations.
4. The distance between the persistent lethal gene and SD gene is so short that its retention in the population may be effectively due to its association with SD. Heterotic gene complexes including the lethal and SD genes were discussed as a persistent mechanism.
5. The sensitivity of the second chromosomes to SD action varied from complete sensitiveness (k=1.0) to resistance (k=0.5). The mean k value of many chromosomes isolated from Kofu and Katsunuma populations was 0.77.View full abstractDownload PDF (1154K) -
M. OGAKI, E. NAKASHIMA-TANAKA, S. MURAKAMI1967 Volume 42 Issue 6 Pages 387-394
Published: 1967
Released on J-STAGE: May 21, 2007
JOURNAL FREE ACCESSAn ether resistant female fly appeared from a radioresistant Mino-H strain, and the offspring of this fly was selected for resistance successively by deep etherization. It was found that the selection pressure was effective. The ether resistant strains which have been selected for 13 generations and 28 generations are called Eth-13 and Eth-28 strains respectively. Quick Sand wild-type strain is susceptible as are also two mutant strains, bar-3 ca and bw; st; svn. In general, the females are more resistant than the males in each strain. Reciprocal crosses showed that resistance to etherization was completely dominant over sensitivity and that maternal or cytoplasmic effects were negligible. The third chromosome is mainly responsible for ether resistance, and the locus of the major gene(s) for ether resistance may be around 61±, and minor genes are also found on the X-chromosome and on the fourth chromosome. We assume that the major genes for resistances to nicotine sulfate, to etherization and to radiation are different from each other at the present status of our experiments.View full abstractDownload PDF (751K) -
AIZO MATSUSHIRO1967 Volume 42 Issue 6 Pages 395-404
Published: 1967
Released on J-STAGE: May 21, 2007
JOURNAL FREE ACCESSDownload PDF (987K)
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