Woodchucks (Marmota monax) with cysticercosis or with liver cancer induced by WHV were successf my operated under GOF anesthesia.
Premedication was carried out with atropine sulfate (0.05 mg/kg, IM), acetylpromazine maleate (0.05 or 0.10 mg/kg, IM) and ketamine hydrochloride (20 mg/kg, IM) . Approximately 15 min after the premedication, the animals were well sedated and easily and safely restrained.
After mask in halation of GOF, they were intubated and maintained with 1-1.5% halothane (O₂: N₂O=1: 1) . During the surgery, changes in heart rate, respiratory rate and body temperature were not significant, except in the woodchuck with cysticercosis, in which dopamine was infused during the rest of the surgery.
Recovery from the anesthesia was very fast in all the animals except the one with cysticercosis and tracheal tubes were removed in approximately 10 min after the end of the halothane inhalation.
These results suggest that GOF anesthesia with this type of premedication is safe and practical in the surgery of woodchucks.

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マウスの麻酔におけるイソクスプリンとエーテルおよびペントバルビタールナトリウムの併用効果について検討した。
その結果, イソクスプリン2mg/kg, 10mg/kgを皮下注射して5分後に, マウスをエーテル10ml添加した麻酔ジャーで60秒間曝露すると, 死亡例はほとんど無く, 麻酔持続時間は, 対照群 (生理食塩液およびアトロピン) より2～3倍延長した。また, 麻酔の導入後, エーテルを0.1ml添加した追加麻酔の実験においても, 同様に対照群よりも麻酔持続時間が長くなった。さらに, イソクスプリン前投与は麻酔ジャーへのエーテルの添加量を半量の5mlに減量してもマウスでは十分な麻酔が得られ, 麻酔持続時間は, 対照群での10mlのエーテルを添加した時の成績に匹敵した。
ペントバルビタールナトリウム50mg/kgによる腹腔内注射麻酔においても, イソクスプリン10mg/kgの前投与により, 麻酔持続時間は, 対照群の約2倍 (平均79分35秒) に延長した。
以上のことから, イソクスプリンを麻酔の前処置薬として用いることにより, 麻酔持続時間が長くなることが明らかとなった。

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Localized osteomyelitis of the metacarpus IV (Mc IV) was successfully treated surgically in a steer. The patient showed severe lameness at the affected limb with a moderate swelling and a fistula with purulent discharge. Radiography revealed a sharply delineated bone piece (sequestrum) with a radiolucent zone at the Mc IV. In addition, periosteal new bone formation, the thickened cortex and increased medullary density were observed. Sequestrectomy was performed under xylazine sedation and local anesthesia. After the removing, the surgical wound was kept open for irrigation and the casting external fixation was employed. Swelling of the limb and the lameness diminished in approximately 3 weeks.

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