The irrigation efficacy of acidic water and a povidone iodine solution were examined in this study. Sterilized and distilled water was adopted as a control. Acidic water was produced using a special system (Asahi Glass Engineering Co. Ltd.). Before in vivo experiments, pH, oxidation-reduction potential, and potency of chloride ion (PCI) of Acidic water were tested in vitro to examine to what extent Acidic water will deteriorate under 6 different conditions of preservation in a capped bottle made of polyethylene terephthalate. The best results were obtained when acidic water was not exposed to air. During the testing period, the pH of the acidic water was unchanged. Heating to 40°C did not affect its nature. When acidic water was put in contact with animal skin or serum, PCI decreased. For in vivo experiments using seven cats, six skin lesions on the dorsal area of each animal were created aseptically, and a solution containing a measured number of Pseudomonas aeruginosa was pored onto each wound as an infection model. Then the wounds were divided into three groups and they were respectively irrigated with acidic water povidone iodine solution, or distilled water. Activity of Pseudomonas aeruginosa in each lesion was examined 24 hours after the irrigation. Macrophotographs of the lesions were taken and the size of each lesion was analyzed by computer. At biopsy, they were also examined for two weeks histopathologically. There were no differences between two tested groups. In the control, shrinkage rate of the wound showed the highest value 2 weeks after the start of the experiment. From these observations, we could not confirm the irrigation efficacy of the acidic water.
A nine-year-old female american shorthaired cat was brought in for treatment with the complaints of anorexia, vomiting, and icterus. Radiographic and ultrasonograghic findings were most suggestive of hepatic tumor. On the 5th hospital day, an exploratory laparotomy was performed because symptomatic treatment did not improve the general condition. Soft tumorous lesions measuring 2 to 70 mm in diameter with a large number of scattered nodules were found at the margins of the hepatic lobes. The duodenum was also observed to be adherently compressed by the heparic tumor, which made us decide against a radical operation. The tissues obtained at biopsy were examined by immunocytochemical and electron microscopic methods. From the results, the diagnosis of feline hepatic carcinoid tumor was established. This kind of tumor in the cat has rarely been reported previously. The patient died on the 55th day after surgery.
A ten-year-old female american-short-hair cat was brought in with paralyzed rear limbs. The cat showed dorsal swelling and induration between the 1st and the 3rd lumbar vertebrae, and absent pulsation on the femoral artery. Radiography and ultrasonography revealed that there were intra-abdominal cysts which had invaded the lumbar vertebrae. After draining liquid from these cysts, pulse on the femoral artery became palpable, but the rear paralysis did not improve. Myelography suggested the presence of spinal cord compression. A dorsal laminectomy from L1 to L3 was performed, but the rear paralysis still remained. The cat died five days after the surgery. At necropsy, the right kidney was highly hydronephrotic and adhered tightly to the ventral side of the vertebral bodies from L1 to L3. Histological diagnosis of the disease was an adenosquamous carcinoma originating from transitional epithelium of the renal pelvis or the ureter.
A five-month-old female cat with continuous vomiting after weaning was brought in for treatment. Blood chemistry tests showed erythrocytosis. Chest X-ray examination showed enlargement of the right heart and narrowing of the trachea near the heart between the 4th and 6th intercostal spaces. Additionally, the left ventricle was enlarged and the aortic arch was deviated to the right. With contrast medium, the esophagus was seen to have a slight stenosis near the cardiac wall. Endoscopical examination revealed that there was a narrow part at the middle of the esophagus. This narrow part inflated during exhalation. An ventricular septal defect was found by means of echo cardiograph. So the patient was surgically treated. A left thoracotomy was performed through the 4th intercostal space. After preparation of the surrounding tissue, the arterial ligament was ligated and cut off. After this procedure, the esophagus was confirmed to have regained its normal shape by insertion of a balloon catheter from the mouth. The chest wound was closed normally. On day 41, blood tests showed no erythrocytosis. On day 100, chest X-ray examination showed normal appearance. The animal has been in good health for three years after surgery. It was also confirmed that the ventricular septal defect had closed spontaneously.