Two canine cases of severe supravalvular pulmonary stenosis were surgically corrected by pulmonary arteriotomy and excision of the membranous stenosis under beating heart using cardio-pulmonary bypass system. For each patient, extracorporeal circulation was finished within half an hour and it took only a few minutes to excise the membraneous stricture. Outcomes were very good for each patient being able to leave hospital within 10 days. Postoperative examinations showed that the pressure gradient decreased adequately with expansion of the narrow area and there were no sign of restenosis in each case. This report suggest that this technique is available not only for supravalvular but also valvular, which is common in dogs, pulmonary stenosis.

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A twelve-year-old shih tzu dog was referred to us with progressive enlargement of the abdomen. Physical and radiographic examinations revealed a large abdominal mass surrounded by peritoneal fluid. The ascitic fluid was denatured and had high viscosity. On the 21st day, the dog had a surgical operation for resection of the mass to improve the dog's quality of life. The removed mass was weak and jelly-like, involving the right adrenal gland, and was diagnosed histopathologically as myxosarcoma. On the 73rd day, a second surgery was done because a similar fluid and mass were detected in the abdomen, which had become larger again. On the 115th day, recurrence was found again, but no further treatment was given at the pet owner's request. Although the dog died on the 133rd day, its quality of life had been better than it might have been without the repeated surgeries.

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We report a canine caval foramen hernia, which is rare in dogs. A four-year-old female Yorkshire terrier which had been slightly lethargic since infancy was referred to us for a close checkup. Thoracic radiography revealed a tumor near the vena cava inferior, which had the same echo level as the liver on ultrasonographs. A lung cancer or a hernia being suspected, computerized tomography and a surgical operation were conducted, and the tumor was successfully resected. Part of the liver seemed to have herniated through the vena cava foramen. Since the tumor consisted of normal liver tissues pathologically, the disease was to be a caval foramen hernia. The dog has become more active after surgery.

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In order to elucidate the suppressive effect of Hatakeshimeji (Lyophyllum decastes Sing.) extract on leukocytopenia, the degree of carboplatin-induced myelosuppression was compared between two groups of dogs; each group was daily given Hatakeshimeji extract or only its placebo for 5 weeks, and on day 7, carboplatin, an anticancer agent, was given intravenously to all dogs. Hematological analyses revealed that the numbers of leukocytes and neutrophils were both significantly higher in the group given Hatakeshimeji extract than in the placebo group. This indicated that Hatakeshimeji extract can suppress carboplatin-induced myelosuppression.

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