The efficacy and safety of a difluprednate ophthalmic solution 0.05% were evaluated clinically against canine uveitis. This drug was administered to 33 cases, 26 cases were available for evaluation, and cases that did not meet our criteria were omitted. Efficacy was evaluated as remarkable in 20 cases (76.9%), as good in five cases (19.2%), and as unchanged in only one case (3.8%). Namely, the cumulative curative rate was extremely high (96.2%). To check for side effects, intraocular pressure was measured in each case. Intraocular pressure was 10.1 ± 3.8 mmHg (mean ± standard deviation) before the start of the topical instillation. On day 7 ± 2, the pressure was 12.8 ± 2.9 mmHg, and on day 14 ± 3, the pressure was 14.4 ± 9.4 mmHg, which indicated significant increases, but were still normal values. There were two adverse cases: one case with irritation at the time of topical instillation, and the other with abnormally increased intraocular pressure. Consequently, remarkable efficacy against canine uveitis of a 0.05% difluprednate ophthalmic solution was shown, although attention should be paid to intraocular pressure.
This study examined the puncture methods and the utility of percutaneous laser disc decompression (PLDD) in dogs with intervertebral disc disease (IVDD). The punctures were possible using procedures that were suitable for each area (cervical, thoracolumbar, and lumbosacral areas). The Clinical laser irradiation condition was set to 3 W, 70 J by the result of basic study. Nine of the 12 dogs (75%) of the thoracolumbar cases, two of 4 dogs (50%) of the cervical casese were improved 1 month after undergoing PLDD. Based on the above, this study showed the safety and effectiveness of PLDD using diode laser for dogs with IVDD. It was suggested that PLDD was useful as a new treatment of IVDD.
In a six-year-old, black-tailed prairie dog (Cynomys ludovicianus) with a chief complaint of inappetence, a tumor was found in the sublingual region of the oral cavity. Administration of an antibiotic, painkiller, and vitamin tablets, etc. for seven days was ineffective, and the tumor was removed surgically. Histopathologically, the tumor had grown in the connective tissues under the mucous epithelium, and it was diagnosed as an adenocarcinoma originating from the salivary gland.
A seven- year-old castrated shizu was brought to our hospital with a chief complaint of recurrent urolithiasis and its accompanying cystitis. Imaging studies showed enlargement of the left renal pelvis and proximal ureter was found, and uroliths were identified in the renal pelvis, ureter, and bladder. Ureterotomy and cystotomy were performed, and the calculi were removed. For fear of potential ureteral obstruction due to swelling of the ureteral mucosa, a nephrostomy tube was implanted.After opening of the ureter was confirmed by urography via the nephrostomy tube, the tube was removed out on postoperative day 5. No urinary problems have been observed for two months since the surgery. Thus, temporary use of a nephrostomy tube may be useful in preparing for potential urinary tract obstruction after ureterotomy.