A 13-year-old male Cavalier King Charles Spaniel weighing 5.7 kg developed weight loss and exercise-induced breathing difficulty. Visual examination under general anesthesia revealed a plaque-like oropharyngeal mass measuring 5×3 cm. The mass occupied the oropharynx between the soft palate and the buccal mucosa bilaterally; however, the tonsils were unaffected. Following debulking surgery, the dog developed cardiac arrest and could not be resuscitated. A postmortem examination was performed. Histopathological examination of the mass, as well as lymph node and lung specimens revealed a characteristic pattern of infiltrating adenocarcinoma concomitant with squamous cell carcinoma, and the dog was diagnosed with stage IV oropharyngeal adenosquamous carcinoma (ASC). ASC should be considered in the differential diagnosis of oropharyngeal tumors in dogs.
A 5-year-old female Pomeranian was admitted for stridor on exertion during the past 2 months. Epiglottic retroversion was confirmed as the diagnosis based on fluoroscopy and laryngoscopy. The dog underwent permanent epiglottopexy. However, stridor recurred on day 6 because of epiglottopexy failure. On day 9, partial epiglottectomy was performed, and the stridor disappeared immediately following the surgery. The dog remains well without complications 45 months postoperatively.
We administered metronomic chemotherapy containing cyclophosphamide as adjuvant chemotherapy for feline mammary adenocarcinoma at clinical stage Ⅲ in three cases. The survival times in the three patients were 271days, 814 days and 261 days respectively. These survival times were longer than those following surgical monotherapy in stage Ⅲ cases. In all cases, patients' quality of life was maintained well without adverse effects. Our protocol may be a possible choice of adjuvant chemotherapy for feline mammary adenocarcinoma, although we must accumulate more cases to validate this.
Feline pancreatic cysts are uncommon, and there have been four relevant cases reported previously, including two cases of true cysts and two cases of pseudocysts. The present case involved an 11-year-old cat, which was diagnosed with a pancreatic cyst at the referring animal hospital, underwent paracentesis, and received medications. Although the cat showed temporal improvement, several clinical symptoms such as vomiting, anorexia, and jaundice then developed. The cat was referred to our hospital for surgical treatment. On surgical exploration, the cyst was found to harbor severe adhesions with surrounding tissues, and the common bile duct and pancreatic duct were obstructed or constricted by the cyst. A cyst-to-duodenum anastomosis was established because the positions of the cyst and duodenum were suitable for this procedure. After the surgery, the cat’s condition and hyperbilirubinemia improved greatly. Moreover, the size of the cyst gradually decreased during the postoperative course. Pathological evaluation revealed that the cyst was a consequence of no neoplastic changes and chronic, proliferative, pleocellular inflammation. The lack of epithelial lining indicated that this pancreatic cyst was a pancreatic pseudocyst secondary to inflammation. This is the first report of a pancreatic pseudocyst that was treated via a cyst-to-duodenum anastomosis, resulting in an improvement in the clinical symptoms and alleviation of hyperbilirubinemia.