Journal of Animal Clinical Medicine
Online ISSN : 1881-1574
Print ISSN : 1344-6991
ISSN-L : 1344-6991
Volume 21 , Issue 4
Showing 1-9 articles out of 9 articles from the selected issue
Specail Contribution
Original Article
  • Masayuki KOBAYASHI, Yukari KITAMI, Shinya YAMAMOTO, shu NAKAO, Takayuk ...
    2012 Volume 21 Issue 4 Pages 157-164
    Published: December 28, 2012
    Released: April 02, 2014
    JOURNALS FREE ACCESS
    Using liver biopsy specimens obtained from 55 dogs which had received surgical attenuation of a congenital extrahepatic portosystemic shunts, hepatic histopathologic findings were reviewed in relation to such clinical findings as age at diagnosis, presence or absence of clinical signs, shunt type, maximal diameter and total length of the shunting vessel, portal pressure before (baseline) and after ligation, change in portal pressure from the baseline, mortality rate following surgery, and survival rate. Histopathologic abnormalities (hepatocellular damage, dilatation of sinusoids, remodeling of the lobular structure, biliary proliferation, hypoplasia of intrahepatic portal veins, arteriolar proliferation, lipid granulomas, lymphangiectasis, and fibrosis) were classified, and the correlation between the histopathologic and clinical findings were statistically analyzed. The results showed that both hypoplasia of intrahepatic portal veins and dilatation of sinusoids were milder in older dogs. On the other hand, lipid granuloma formation was more extensive in older dogs. The hypoplasia of intrahepatic portal veins was severer in dogs with neurological abnormalities (seizure or ataxia) or delayed growth, in comparison with dogs with no apparent clinical signs. There was no significant correlation of the histological features examined here with shunt type, maximal diameter and total length of the shunting vessel, portal pressure between before (baseline) and after ligation, or change in portal pressure from the baseline. In dogs that died following surgery, hepatocellular damage, biliary proliferation, hypoplasia of intrahepatic portal veins, and lymphangiectasis were more extensive, as compared with surviving dogs. In conclusion, there was a significant correlation between the severity of hypoplasia of intrahepatic portal veins and such clinical signs as age at diagnosis, presence or absence of clinical signs, and mortality rate after surgery, which suggested that hypoplasia of intrahepatic portal veins might be the most correlative indicator of the clinical findings observed in dogs with congenital extrahepatic portosystemic shunt.
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  • Shingo HATOYA, Masaru FURUYA, Hideo AKIYOSHI, Hiroyuki TANI, Eriko SHI ...
    2012 Volume 21 Issue 4 Pages 165-169
    Published: December 28, 2012
    Released: April 02, 2014
    JOURNALS FREE ACCESS
    One hundred and thirty-one strains of the Staphylococcus intermedius group (SIG), 39 strains of coagulase negative Staphylococci (CNS), and 8 strains of S. aureus (SA) were isolated from bacteria-infected dogs and cats brought to Osaka Prefecture University Veterinary Medical Center from 2009 to 2011. Forty-nine percent of SIG (64 strains), 46 percent of CNS (18 strains), and 25 percent of SA (2 strains) were methicillin-resitant (MR). More than 80 percent of strains of MRSIG were sensitive to tetracycline, doxycycline (DOXY), minocycline (MINO), or vancomycin (VCM); more than 80 percent of MRCNS were sensitive to clindamycin, MINO, trimethoprim-sulfamethoxazole (ST), or VCM; and more than 80 percent of MRSA were sensitive to DOXY, amikacin, chloramphenicol, ST or VCM.
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  • Eriko SHIMADA, Tadashi MIYAMOTO, Yui KIMURA, Mai KAKUMOTO, Shingo HATO ...
    2012 Volume 21 Issue 4 Pages 170-179
    Published: December 28, 2012
    Released: April 02, 2014
    JOURNALS FREE ACCESS
    Minimum growth inhibitory concentrations of antibacterial agents were determined using a broth-microdilution method, and antibacterial activity of each drug was assessed in clinical isolates from dogs and cats which had been brought to our animal hospital in Yamaguchi City in 2011. Twenty percent of strains of the Staphylococcus intermedius group (SIG), 10 percent of strains of coagulase negative Staphylococci, and 33 percent of strains of S. aureus were methicillin-resistant (MR). Although MR Staphylococci were resistant to many antimicrobial drugs, MRSIG were sensitive to minocycline, arbekacin, linezolid, vancomysin, and teicoplanim. Enterococcus spp., especially E. faecium, were resistant to many drugs. Twenty-four percent of strains of Escherichia coli and 17 percent of strains of Klebsiella pneumoniae were productive of extended - spectrum β-lactamase. Twenty-four percent of strains of E. coli and 6 percent of strains of Pseudomonas aeruginosa were resistant to fluoroquinolone. Since various kinds of resistant bacteria were isolated from dogs and cats in this survey, attention needs to be paid to the trend toward resistance to antibacterial agents.
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Case Report
Short Report
  • Katsutoshi TABATA, Kuniyoshi YASUKAWA, Keitarou MORISHITA, Takashi UEN ...
    2012 Volume 21 Issue 4 Pages 190-194
    Published: December 28, 2012
    Released: April 02, 2014
    JOURNALS FREE ACCESS
    A spayed Labrador retriever, 13 years and 2 months old, was referred to our hospital because of intraabdominal mass and hemorrhage. By computed tomography, the mass was diagnosed as adrenal adenoma in the left, and it was removed surgically. Histopathological examination showed suspicion of an adrenal adenoma. Before surgery, alkaline phosphatase activity and total cholesterol were high, and diarrhea and anorexia continued after surgery. Serum cortisol concentration after injection of ACTH remained low. From these findings, this adrenal tumor was considered to be functional. Consequently its surgical removal was considered to have caused temporary adrenal insufficiency. The dog has been in good condition for 16 months until now.
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