A study was designed to observe the mechanical effect of a dental chew on periodontal health in adult dogs. The accumulation of dental plaque and dental calculus, and the development of gingivitis were assessed in two groups of dogs; one fed a dry diet only and the other group fed the same dry diet with the daily addition of the dental hygiene chew. The study was conducted as a two period parallel cross-over trial where each period consisted of a 14 day pretest phase followed by a 28 day test phase. Dogs fed a single daily dental chew had significantly less plaque (54.8%, p=0.001) and calculus (62.0%, p=0.02) compared with dogs in the control group that were fed an identical diet but received no chews. The daily addition of the chew also reduced the severity of gingivitis (53.8%, p=0.04) as compared to feeding the dry diet only. Accumulation of plaque and calculus on carnassial (maxillary fourth premolar and mandibular first molar) and maxillary first molar were significantly reduced by 56.6% (p=0.0002) and 66.0% (p=0.001) respectively. No significant effect of mechanical plaque and calculus reduction was observed on canine teeth and incisors. It is suggested that mechanical reduction of plaque and calculus by chewing this products is significant on carnassial teeth and maxillary first molar but not on canines and incisors.

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A 13 year-old female beagle was admitted with recurrent tumors in the skin extending from the third right cranial nipple to the left medial femoral region. Although The tumors, which had been present for 4 years, and were resected twice, however recurrence occurred. An initial histopathological diagnosis was invasive trichoepithelioma. Wide restriction was performed at our university hospital and our revised histopathological diagnosis was malignant trichoepithelioma. On the 56th day of illness (7 weeks after surgery), recurrence occurred again in the skin around the inguinal region. On the 127th day of illness (17 weeks after surgery), painful bone metastases to the lumbosacral to the caudal vertebrae were confirmed. From the 133rd day of illness, palliative radiotherapy for the bone metastases was performed to improve pain and quality of life. From the 148th day of illness, bisphosphonates (zoledronic acid) were administered to inhibit bone resorption and alleviate pain. Although the dog died at home on the 394th day of illness, pain had not increased and the dog was able to walk with good quality of life for the remainder of its life.

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A noncastrated Maltese, one-year-old, was presented with generalized tremor all of a sudden. Upon general physical examination, its body condition was normal, but severe tremor was presented all over and it had difficulty in walking. There were no abnormalities in the neurological examination except the lack of bilateral menace responses, and in the blood examination and radiography. The dog was tentative diagnosed generalized tremor syndrome in several examination and treated with immunosuppressive doses of prednisolone and diazepam. Tremor was decrease on the first day after the treatment, but the lack of bilateral menace response was continued. After 22 days from setting on treatment, there were no abnormalities in the magnetic resonance imaging of its brain and cerebrospinal fluid analyses. After 133 days at setting on treatment, treatment was stopped and tremor didn't have a recurrence. However, menace response deficits remained and we can't make this cause clear.

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