We report two cases of pure red cell aplasia (PRCA) in feline leukemia virus (FeLV) positive cats, both of which were treated successfully by immunosuppressive therapy. A seven-year-old female cat and a two-year-old male cat both infected with FeLV were brought to us with anorexia. Complete blood count indicated non-regenerative anemia, and bone marrow tests revealed severe hypoplasia of only erythroblasts. The disease was diagnosed as PRCA, and treated by immunosuppressive therapy with cyclosporin in combination with pulse therapy with methylpredonisolone. PRCA caused by FeLV infection has been reported to be unresponsive to immunosuppressive therapy, but in these cases it was effective. The results might suggest that erythroblast precursor be destroyed due to some immuno-mediated mechanism even in secondary PRCA in FeLV positive cats.
This is a case report of successful cryosurgical treatment for limbal masses in the left eye of a two-year-old, flat-coated retriever. Topical treatment could not suppress the growth of the tumors. In gonioscopy no lesion could be observed in either the iridocorneal angles or the internal surface. Lamellar corneoscleral excision and biopsy were performed, and melanoma was conformed histologically. Since the melanoma was developed again at the same site one month after the surgery, it was removed by cryosurgery. The dog has been in good condition without recurrence for 18 months since the cryosurgery, although lipid keratopathy has persisted in the left eye.