巻号一覧
39 巻, 5 号
選択された号の論文の8件中1～8を表示しています
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樫本 修, 伊藤 利之, 山口 明, 佐伯 覚, 佐々木 鐵人, 住居 広士, 中島 咲哉, 永田 雅章, 原行 弘2002 年 39 巻 5 号 p. 219-223
発行日: 2002/05/18
公開日: 2009/10/28
ジャーナル フリーPDF形式でダウンロード (3708K) -
平上 二九三, 加納 良男2002 年 39 巻 5 号 p. 229-235
発行日: 2002/05/18
公開日: 2009/10/28
ジャーナル フリー我々はマウス線維芽細胞と人工骨(HA)を混合培養し,いろいろな刺激を与えると細胞がHAの周りに三次元様増殖することを見い出した.今回は骨形成促進に有効とされる物理刺激に焦点を合わせ,その効果を調べた.三次元様増殖の形成率は,電磁場刺激1Gを16時間与えたものは無処理対照群の2.8倍であったが24時間では9.4倍,48時間では16.0倍誘導された.電気刺激は誘導がみられなかった.超音波は5W/cm2の3秒照射で誘導がなかったが6秒では4.2倍,9秒では4.0倍誘導された.レーザーは1J/cm2照射で6.3倍,5J/cm2で3.7倍の誘導がみられたが16J/cm2では対照の1/10となった.この結果から物理刺激にはどれも適刺激があることが判明した.抄録全体を表示PDF形式でダウンロード (3146K) -
山内 秀樹, 刈谷 文彦, 田端 淳一, 宮野 佐年2002 年 39 巻 5 号 p. 236-244
発行日: 2002/05/18
公開日: 2009/10/28
ジャーナル フリー生後6ヵ月齢のFischer 344系雌ラットを用い,1,3,8週間の非荷重による筋萎縮とミオシン重鎖(MHC)分子種の発現変化について検討した.ヒラメ筋(SOL)では筋原線維蛋白濃度の減少が非荷重3週間以降に観察されたが,足底筋(PLA)と内側腓腹筋(MG)では非荷重8週間まで変化が認められなかった.したがって,速筋における筋重量変化は,機能的な萎縮率を反映するが,SOLでは筋原線維蛋白濃度の低下を伴うため,筋重量変化は機能的な萎縮率を過小評価すると考えられた.MHC分子種組成はSOLではMHC Iの減少とMHC IIxの増加が,PLAではMHC I,IIaの減少とMHC IIbの増加が,MGではMHC IIxの減少とMHC IIbの増加が観察された.すなわち,MHC分子種は,いずれの筋においてもMHC IからIIb方向への発現変化が認められたが,筋により変化の程度は異なるものであった.PLAとMGではMHC分子種の発現変化は非荷重8週間においてのみ観察されたが,ヒラメ筋では非荷重3週間でMHC IIaが減少し,通常ほとんど発現していないMHC IIxの発現が認められた.以上の結果は,MHC分子種の発現変化は速筋に比べて遅筋のSOLで先行し,また,そのシフトはMHC IからIIaへの変化に比べMHC IIaからIIxへの変化が先行することを示唆する.抄録全体を表示PDF形式でダウンロード (2212K) -
川口 祥子, 竹内 孝仁, 穐山 尚子, 長田 優香, 大矢 亜野2002 年 39 巻 5 号 p. 245-248
発行日: 2002/05/18
公開日: 2009/10/28
ジャーナル フリーWe report a case involving a patient who underwent rehabilitation following onset of pons tegmentum hemorrhage. The initial diagnosis was a disorder of paramedian pontine reticular formation (PPRF), but this was changed over the course of observation to bilateral medial longitudinal fasciculus (MLF) syndrome and dissociation associated with vertical nystagmus. Reports of rehabilitation in a patient with a severe disturbance of ocular motility are rare. Improvement was seen in bilateral abduction and adduction of the right eye, but no improvement was seen in adduction of the left eye or in vertical nystagmus during forward and vertical gaze. Lateral gaze disturbances, possibly present due to hematoma-associated pressure, may have improved spontaneously over time, with rehabilitation using convergence movement helping to shorten the time to improvement, suggesting that such treatment is effective in improving lateral gaze disturbances. However, the vertical gaze nystagmus in this patient was thought to be irreversible, given that the ascending medial longitudinal fasciculus had been severed as a result of the pontine hemorrhage, which prevented the development of a mechanism to compensate for it.抄録全体を表示PDF形式でダウンロード (1723K) -
竹川 徹, 植松 海雲, 安保 雅博, 大熊 るり, 殷 祥洙, 宮野 佐年2002 年 39 巻 5 号 p. 249-252
発行日: 2002/05/18
公開日: 2009/10/28
ジャーナル フリーWe encountered a case strongly suspected of paraneoplastic limbic encephalitis (PLE). PLE is a rare syndrome characterized by neurological signs and symptoms originating from the remote effects of cancer, and these symptoms are accompanied by malignant tumor, mostly small cell lung carcinoma. A 64-year-old woman had gradually increasing symptoms of anxiety, recent memory disorder, disorientation, and agitation. She was admitted to a hospital complaining of mild fever, epilepsy, and somnolence about one month later, on August 10, 2000. Brain metastasis and viral encephalitis were excluded. She was transferred to our hospital for further rehabilitation treatment on December 20, 2000, with reduced spontaneity and double hemiplegia. Although no definitive diagnosis was made, we provided her with rehabilitation to maintain her body function, and also gave mental support to her family with the aim of home discharge. As her symptoms improved, she could go out for short periods. Because some tumor markers were high, malignant disease was suspected. She underwent various examinations, and a biopsy showed small cell carcinoma of the lung. The clinical symptoms and other findings strongly suggested PLE with small cell carcinoma of the lung. Her general condition was too poor to permit chemotherapy, so she was maintained only on symptomatic therapy, and rehabilitation was changed to palliative care. She died about five month after hospitalization.抄録全体を表示PDF形式でダウンロード (1122K) -
橋本 圭司, 大橋 正洋, 渡邉 修, 宮野 佐年2002 年 39 巻 5 号 p. 253-256
発行日: 2002/05/18
公開日: 2009/10/28
ジャーナル フリーA thirty-seven-year-old man with cognitive, emotional and behavioral dysfunction due to anoxic encephalopathy after a myocardial attack was admitted to our hospital. The purpose of this hospitalization was to evaluate his impairment and to help his family to care him at home. His brain dysfunction was so severe that he could not participate in the ordinary rehabilitation program. Because of his condition, our rehabilitation team and his wife communicated closely to obtain mutual agreement about the way to deal with his difficult behavioral problems. The therapists treated him with whatever the way that can bring up patient's better responses. As a result of such transdisciplinary team (TDT) approach for about five months, he became to show less problematic behaviors and to be able to live with his family at home. The TDT approach is reported to be effective to those who have cognitive and behavioral problems such as this patient.抄録全体を表示PDF形式でダウンロード (590K) -
西脇 香織, 近藤 国嗣, 里宇 明元, 千野 直一2002 年 39 巻 5 号 p. 257-266
発行日: 2002/05/18
公開日: 2009/10/28
ジャーナル フリーPeripheral nerves have a potency to regenerate vigorously after injury, but often it is difficult to achieve a sufficient functional recovery. Although advances in microsurgery and a better understanding of nerve regeneration have improved the outcomes of nerve repair, a delayed and misdirected reinnervation still be a problem hindering functional restoration. Rehabilitation managements of peripheral nerve injury, such as electrical stimulation, exercise training and other approaches, have been in clinical use, but their effects on promoting reinnervation remain controversial. In this paper we review the basic studies which have investigated the mechanisms and efficacies of electrical stimulation, exercise training and motor/sensory reeducation. Electrical stimulation could elicit effects on the regenerated nerves, but inappropriate stimulation conditions might disturb regeneration. Exercise training often improves functional recovery after nerve injury, but overloaded and forced exercise might have a detrimental effect. The peripheral axonal misdirection is reflected in a cortical reorganizational changes. Some studies have revealed beneficial changes in the cortical map after motor/sensory reeducation programs in monkeys with nerve injury, which may explain the improved functional outcomes after rehabilitation in humans.抄録全体を表示PDF形式でダウンロード (1582K) -
2002 年 39 巻 5 号 p. 267-272
発行日: 2002/05/18
公開日: 2009/10/28
ジャーナル フリーPDF形式でダウンロード (805K)
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